Results 51 to 60 of about 211,010 (368)

Secretory Leukoprotease Inhibitor: A Native Antimicrobial Protein in the Innate Immune Response in a Rat Model of S. aureus Keratitis

open access: yesJournal of Ophthalmology, 2009
Purpose. To describe the presence of secretory leukocyte protease inhibitor (SLPI), a cationic peptide with antimicrobial and antiprotease activity in the innate immune reaction in a rat model of Staphylococcus aureus keratitis. Methods.
Victor E. Reviglio   +5 more
doaj   +1 more source

Triangulation and persistence: Algebra 101 [PDF]

open access: yesarXiv, 2021
This paper lays the foundations of triangulated persistence categories (TPC), which brings together persistence modules with the theory of triangulated categories. As a result we introduce several measurements and metrics on the set of objects of some triangulated categories.
arxiv  

Current and Future Cornea Chip Models for Advancing Ophthalmic Research and Therapeutics

open access: yesAdvanced Biology, EarlyView.
This review analyzes cornea chip technology as an innovative solution to corneal blindness and tissue scarcity. The examination encompasses recent developments in biomaterial design and fabrication methods replicating corneal architecture, highlighting applications in drug screening and disease modeling while addressing key challenges in mimicking ...
Minju Kim   +3 more
wiley   +1 more source

Non-contact acoustic micro-tapping optical coherence elastography for evaluating biomechanical changes in the cornea following UV/riboflavin collagen cross linking: ex vivo human study [PDF]

open access: yesarXiv, 2022
Purpose: To evaluate changes in the anisotropic elastic properties of ex vivo human cornea treated with UV cross-linking (CXL) using non-contact acoustic micro-tapping Optical Coherence Elastography (AuT-OCE) Design: AuT performed on normal and CXL ex vivo human donor cornea Methods: Elastic properties of normal and UV CXL treated human corneas were ...
arxiv  

Cornea Preservation Time Study: Methods and Potential Impact on the Cornea Donor Pool in the United States

open access: yesCornea, 2015
Purpose: The aim of this study was to describe the aims, methods, donor and recipient cohort characteristics, and potential impact of the Cornea Preservation Time Study (CPTS).
J. Lass   +13 more
semanticscholar   +1 more source

Intraoral Drug Delivery: Bridging the Gap Between Academic Research and Industrial Innovations

open access: yesAdvanced Functional Materials, EarlyView.
Intraoral drug delivery offers a promising route for systemic and localized therapies, yet challenges such as enzymatic degradation, limited permeability, and microbial interactions hinder efficacy. This figure highlights innovative strategies—mucoadhesive materials, enzyme inhibitors, and permeation enhancers—to overcome these barriers.
Soheil Haddadzadegan   +4 more
wiley   +1 more source

DMEK with endophotocoagulation and cyst wall removal for corneal endothelial decompensation due to iris cyst

open access: yesAmerican Journal of Ophthalmology Case Reports, 2022
Purpose: Iris cysts may arise secondary to surgical or nonsurgical trauma, potentially leading to corneal decompensation via mechanical injury to the adjacent endothelium.
Sam Arnold   +4 more
doaj  

3D (Bio) Printing Combined Fiber Fabrication Methods for Tissue Engineering Applications: Possibilities and Limitations

open access: yesAdvanced Functional Materials, EarlyView.
Biofabrication aims at providing innovative technologies and tools for the fabrication of tissue‐like constructs for tissue engineering and regenerative medicine applications. By integrating multiple biofabrication technologies, such as 3D (bio) printing with fiber fabrication methods, it would be more realistic to reconstruct native tissue's ...
Waseem Kitana   +2 more
wiley   +1 more source

An Unusual Case of Nonhealing Granulomatous Keratitis Caused by Mycobacterium chelonae in a Healthy Middle Aged Adult

open access: yesCase Reports in Ophthalmological Medicine, 2015
Purpose. To report a rare presentation of culture positive Mycobacterium chelonae (M. chelonae) corneal ulcer and its management. Case Report. We report a rare case with history of chronic pain and blurriness of vision.
Vipul Bhandari, Sriganesh, Kirti Relekar
doaj   +1 more source

Simultaneous tensile and shear measurement of the human cornea in vivo using S0- and A0-wave optical coherence elastography [PDF]

open access: yesarXiv, 2023
Understanding corneal stiffness is valuable for improving refractive surgery, detecting corneal abnormalities, and assessing intraocular pressure. However, accurately measuring the elastic properties, particularly the tensile and shear moduli that govern mechanical deformation, has been challenging.
arxiv  

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