Results 81 to 90 of about 233,538 (301)

Differences in localization of P2X7 during epithelial wound healing in pre-type II diabetic models [PDF]

open access: yes, 2017
Corneal injury, accompanied by improper wound repair, is the 4th highest cause of preventable blindness according to the World Health Organization.
Kneer, Krisandra
core  

Highly Biomimetic Ectodermal Epithelial Organoids for Epithelial Barrier Stimulation Assays

open access: yesAdvanced Science, EarlyView.
ABSTRACT Evaluating the potential toxicity of pharmaceuticals and biomaterials to ectodermal epithelia, such as the oral mucosa and skin, is indispensable in pre‐clinical assessments. However, this remains a challenge primarily owing to the lack of physiologically relevant and accurate screening models.
Yiming Chen   +13 more
wiley   +1 more source

The Territorial Organisation of the Subnational Public Power in the Preliminary Constitutional Drafts Developed by the Political Parties in Romania in the Years 1921-1922 [PDF]

open access: yesCodrul Cosminului
One of the most important problems that had to be solved after the establishment of the Unified Romanian State was institutional and legislative unification, which required the elaboration and adoption of a new constitutional framework.
Sergiu CORNEA
doaj   +1 more source

GHRHR Deficiency Enhances Retinal Ganglion Cell Survival and Visual Functions in Experimental Glaucoma by Inhibiting Ferroptosis

open access: yesAdvanced Science, EarlyView.
Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong   +24 more
wiley   +1 more source

In vivo Confocal Microscopy for Corneal and Ocular Surface Pathologies: A Comprehensive Review

open access: yesClinical Ophthalmology
Arturo Ramirez-Miranda,1 Jesus Guerrero-Becerril,1 Manuel Ramirez,2 Guillermo Raul Vera-Duarte,1 Simran Mangwani-Mordani,1,3,4 Gustavo Ortiz-Morales,1 Alejandro Navas,1 Enrique O Graue-Hernandez,1 Jorge L Alio5 1Departamento de Córnea y Cirugía ...
Ramirez-Miranda A   +8 more
doaj  

Diagnostic features of Acanthamoeba keratitis via in vivo confocal microscopy

open access: yesScientific Reports
In vivo confocal microscopy (IVCM) offers a non-invasive, rapid method for diagnosing Acanthamoeba keratitis (AK) by detecting cysts or trophozoites in the initial clinic visit images.
Joanna Przybek-Skrzypecka   +7 more
doaj   +1 more source

A parametric bootstrap for heavytailed distributions [PDF]

open access: yes
It is known that Efron's resampling bootstrap of the mean of random variables with common distribution in the domain of attraction of the stable laws with infinite variance is not consistent, in the sense that the limiting distribution of the bootstrap ...
Adriana Cornea, Russell Davidson
core  

MG53 Coordinates Macrophage Polarization and Neuroimmune Coupling to Promote Corneal Nerve Regeneration via the MPEG1–MVP–STAT6 Axis

open access: yesAdvanced Science, EarlyView.
Corneal nerve regeneration is critical to corneal wound healing processes. The current study reveals a novel role of MG53 in promoting corneal nerve regeneration after alkali induced injury. Mechanistically, MG53 enters macrophages via its receptor, MPEG1, promotes MVP K63 ubiquitination, and triggers STAT6 induced repair‐related genes expression ...
Peng Chen   +14 more
wiley   +1 more source

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