Results 141 to 150 of about 182,932 (248)

Improving outcomes in corneal infections

The cornea is essential for vision. Corneal blindness affects all ages, and is often irreversible. Infection of the cornea is a significant cause of corneal blindness.

core  

Nonclassical ultrasonographic presentation of retinal detachment: Blindness in a 21‐year‐old gelding with equine recurrent uveitis

Equine Veterinary Education, EarlyView.
Summary A 21‐year‐old gelding, with a history of equine recurrent uveitis, was presented for a chronic nonhealing corneal ulcer. Ophthalmic examination of the right eye revealed a deep corneal ulcer, with the presence of corneal neovascularisation, mild diffuse corneal oedema and hypopyon. Additionally, the gelding was blind from the affected eye.
M. van Heule, A. Khachadoorian, M. Wichtel, B. N. Lillie, D. Kenney, A. Merchán Muñoz   +5 more
wiley   +1 more source

A comparative analysis of cell death signalling in RNA and DNA virus infections and potential inhibitory strategies

The FEBS Journal, EarlyView.
RNA and DNA viruses can manipulate host cell death through various mechanisms. RNA viruses (H1N1, SARS‐CoV‐2) induce acute apoptosis, necroptosis, and pyroptosis to promote rapid viral transmission and epithelial barrier damage. In contrast, DNA viruses (HSV‐1, EBV) regulate these mechanisms to sustain a lytic‐latency cycle, evade immune response and ...
Panagiotis Keramidas, Maria Pitou, Amalia Aggeli, Sotiris Varlamis, Theodora Choli‐Papadopoulou   +4 more
wiley   +1 more source

Reduced order modelling of air‐puff test for corneal material characterisation

Journal of Microscopy, EarlyView.
Abstract Models of the fluid–structure interaction (FSI) model for the air‐puff test were analysed. Using Abaqus, the air‐puff test is applied to eyes with varying biomechanical parameters, such as material properties, corneal thickness, and radius.
Osama M. Maklad, Muting Hao
wiley   +1 more source

Incorporating the Competencies of Evidence‐Based Veterinary Medicine Focused on Pharmacotherapeutics Into Clinical Rotations for Small Animal Dermatology and Food Animal Medicine and Surgery at a Veterinary Medical Teaching Hospital in the US

Journal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT Building the skills and knowledge necessary to practice evidence‐based veterinary medicine (EBVM) should occur throughout the veterinary curriculum. Operationalizing EBVM includes asking a clinical question in PICO format, searching the biomedical literature for evidence, critically appraising the evidence, and applying the evidence to make a ...
Virginia R. Fajt, Adam P. Patterson, Dusty Nagy, Jennifer Schleining, Kevin Washburn   +4 more
wiley   +1 more source

Preclinical Target Animal Safety Evaluation of Veterinary Monoclonal Antibodies: Principles, Methods, and Interpretation

Journal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT Monoclonal antibodies (mAbs) represent a rapidly expanding pharmaceutical class in veterinary medicine, with several products now authorized for use in dogs and cats. Limited published articles and veterinarian exposure to the principles of drug development present challenges in interpreting published safety evaluations that inform product ...
Adam Werts, Matthew Kuhn, Lauren Bessey, Alicia Braxton Hickman, Emily Chory, John Mitchell, Kirby Pasloske   +6 more
wiley   +1 more source

Human ocular‐discomfort‐free thresholds for 222 nm Far‐UVC irradiation: A prospective interventional study

Photochemistry and Photobiology, EarlyView.
Eye discomfort induced by 222 nm far‐UVC irradiation is significantly correlated with both irradiance and radiant exposure dose. The red circles indicate conditions with significant differences in the number of eye discomfort compared to the control group (blue circles), while the green circles indicate conditions with no difference from the control ...
Sachiko Kaidzu, Kazunobu Sugihara, Masaki Tanito   +2 more
wiley   +1 more source

Evaluation for endotoxin in intraocular materials used during phacoemulsification surgery using a recombinant factor C assay

Veterinary Ophthalmology, Volume 28, Issue 2, Page 481-485, March 2025.
Abstract Objective Cataract surgery remains the sole method to resolve blindness secondary to cataract formation. One complication includes fibrin web formation post‐operatively. This study aimed to investigate the presence of endotoxin within materials used during cataract surgery as a possible cause of fibrin web phenomenon. Methods Preservative‐free
Taylor A. Opgenorth, Eryn L. Opgenorth, J. Seth Eaton, Ellison Bentley   +3 more
wiley   +1 more source

Vision outcomes in dogs with primary glaucoma surgically treated with lensectomy and endolaser cyclophotocoagulation after an Ahmed valve gonioimplantation failure

Veterinary Ophthalmology, Volume 28, Issue 2, Page 207-217, March 2025.
Abstract Objective The aim of this study was to retrospectively evaluate vision outcomes of dogs with primary angle closure glaucoma (PACG) that underwent Ahmed valve gonioimplantation (AVG) followed by lensectomy and endolaser cyclophotocoagulation (ECP) with or without bleb resection after AVG failure.
Bactelius Turicea, Christian L. Munevar, Sydney G. Edwards, Lana L. Linton   +3 more
wiley   +1 more source

Micropulse transscleral cyclophotocoagulation in canine glaucoma: A retrospective study evaluating sweep velocity

Veterinary Ophthalmology, Volume 28, Issue 2, Page 293-305, March 2025.
Abstract Objective To report preliminary results of MP‐TSCP in canine patients with glaucoma while evaluating sweep velocity, treatment efficacy, and safety utilizing standardized surgical parameters. Animal studied Client‐owned dogs that underwent MP‐TSCP at a veterinary referral hospital. Procedure Medical records of 19 eyes (14 dogs) treated with MP‐
Valeria Benitez‐Vera, Dineli Bras, Fabiano Montiani‐Ferreira   +2 more
wiley   +1 more source