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Diagnosis and management of iridocorneal endothelial syndrome [PDF]
The iridocorneal endothelial (ICE) syndrome is a rare ocular disorder that includes a group of conditions characterized by structural and proliferative abnormalities of the corneal endothelium, the anterior chamber angle, and the iris.
Ambrosio, Oriella+5 more
core +7 more sources
Phase I trial of recombinant human nerve growth factor for neurotrophic keratitis [PDF]
Neurotrophic keratitis/keratopathy (NK), a rare degenerative corneal disease, lacks effective pharmacologic therapies.1 Because NK pathology involves trigeminal nerve damage and loss of corneal innervation, nerve growth factor (NGF) is surmised to ...
Alio, Jorge+45 more
core +1 more source
A proof-of-concept clinical trial using mesenchymal stem cells for the treatment of corneal epithelial stem cell deficiency [PDF]
Producción CientíficaOcular stem cell transplantation derived from either autologous or allogeneic donor corneoscleral junction is a functional cell therapy to manage extensive and/or severe limbal stem cell deficiencies that lead to corneal epithelial ...
Alberca Zaballos, Mercedes+9 more
core +2 more sources
VPA DIGITAL AT YOUR FINGERTIPS
VPA DIGITAL AT YOUR ...
Paulo E.C. Dantas
doaj +1 more source
Non-invasive detection of nanoscale structural changes in cornea associated with cross-linking treatment [PDF]
Corneal cross-linking (CXL) using UVA irradiation with a riboflavin photosensitizer has grown from an interesting concept to a practical clinical treatment for corneal ectatic diseases globally, such as keratoconus. To characterize the corneal structural changes, existing methods such as X-ray microscopy, transmission electron microscopy (TEM ...
arxiv +1 more source
Phase 2 randomized, double-masked, vehicle-controlled trial of recombinant human nerve growth factor for neurotrophic keratitis [PDF]
Purpose: To evaluate the safety and efficacy of topical recombinant human nerve growth factor (rhNGF) for treating moderate-to-severe neurotrophic keratitis (NK), a rare degenerative corneal disease resulting from impaired corneal innervation.
Alio, Jorge+45 more
core +1 more source
Corneal alterations associated with pseudoexfoliation syndrome and glaucoma: A literature review [PDF]
A systematic literature review was performed evaluating articles examining the effects of pseudoexfoliation syndrome (PEX) and glaucoma (PEXG) on the cornea with a focus on the corneal endothelium.
Palko, Joel R+2 more
core +3 more sources