Results 51 to 60 of about 9,089,625 (306)

Characterisation of the role played by ELMO1, GPR141 and the intergenic polymorphism rs918980 in Fuchs' dystrophy in the Indian population

FEBS Open Bio, EarlyView.
This study reports the upregulation of ELMO1 and GPR141 in human Fuchs' endothelial corneal dystrophy (FECD) corneal endothelium and ultraviolet A‐induced FECD mice model. A genetic association of an intergenic single nucleotide polymorphism rs918980 present between both genes is observed with FECD in the Indian population.
Susmita Sharma, Samar Kumar Basak, Sujata Das, Debasmita Pankaj Alone   +3 more
wiley   +1 more source

SmartKC: Smartphone-based Corneal Topographer for Keratoconus Detection [PDF]

arXiv, 2021
Keratoconus is a severe eye disease affecting the cornea (the clear, dome-shaped outer surface of the eye), causing it to become thin and develop a conical bulge. The diagnosis of keratoconus requires sophisticated ophthalmic devices which are non-portable and very expensive.
arxiv  

Bilateral keratoprostheses in a patient with ocular mucous membrane pemphigoid. [PDF]

, 2019
Mucous membrane pemphigoid (MMP) with ocular involvement, also referred to as ocular cicatricial pemphigoid, is a rare, autoimmune blistering disease that can have devastating effects for patients.
Bromley, Jennifer, DeGrazia, Taryn, Feldman, Ron   +2 more
core  

Bilateral Alterations in Corneal Nerves, Dendritic Cells, and Tear Cytokine Levels in Ocular Surface Disease

Cornea, 2016
: This review summarizes the recent literature regarding corneal imaging in human subjects using in vivo confocal microscopy. It also covers the recent literature on corneal immune cells, nerves, and tear cytokine levels in ocular surface diseases as ...
Takefumi Yamaguchi, P. Hamrah, J. Shimazaki   +2 more
semanticscholar   +1 more source

Evaluation of OPTOS wide‐field fundus image projections for radiotherapy planning of uveal melanoma

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose To investigate the relationship between the stereographic and azimuthal equidistant projection (AEP) of the human retina for radiotherapy planning with OPTOS optomap wide‐field fundus images (Optos, UK). Further, the geometric accuracy of an OPTOS fundus image is quantified.
Jörg Wulff, Benjamin Koska, Michael Giese, Christian Bäumer, Ronald Richter, Andreas Foerster, Nikolaos E. Bechrakis, Beate Timmermann   +7 more
wiley   +1 more source

An update and review of narrowband ultraviolet B phototherapy for vitiligo

Dermatological Reviews, Volume 3, Issue 5, Page 326-335, October 2022., 2022
Abstract Vitiligo is a chronic skin condition that results in depigmentation. It affects up to 2% of the population worldwide. Phototherapy is one of the most commonly used treatment methods for vitiligo. In the last few decades, there has been an increasing popularity of narrowband ultraviolet B phototherapy (NB‐UVB) over other forms of phototherapy ...
Eugene Wang, Michelle Rodrigues
wiley   +1 more source

Current and Future Cornea Chip Models for Advancing Ophthalmic Research and Therapeutics

Advanced Biology, EarlyView.
This review analyzes cornea chip technology as an innovative solution to corneal blindness and tissue scarcity. The examination encompasses recent developments in biomaterial design and fabrication methods replicating corneal architecture, highlighting applications in drug screening and disease modeling while addressing key challenges in mimicking ...
Minju Kim, Kanghoon Choi, Amy Lin, Jungkyu Kim   +3 more
wiley   +1 more source

Effect of recombinant human nerve growth factor eye drops in patients with dry eye: a phase IIa, open label, multiple-dose study [PDF]

, 2019
Background: Dry eye disease (DED) affects more than 14% of the elderly population causing decrease of quality of life, high costs and vision impairment.
Allegretti, M., Ferrari, M., Garhoefer, G., Lambiase, A., Mantelli, F., Sacchetti, M., Schmetterer, L., Schmidl, D.   +7 more
core   +1 more source

Pilot Study for OCT Guided Design and Fit of a Prosthetic Device for Treatment of Corneal Disease

Journal of Ophthalmology, 2012
Purpose. To assess optical coherence tomography (OCT) for guiding design and fit of a prosthetic device for corneal disease. Methods. A prototype time domain OCT scanner was used to image the anterior segment of patients fitted with large diameter (18.5 ...
Hong-Gam Le, M. Tang, Ryan Ridges, David Huang, D. Jacobs   +4 more
semanticscholar   +1 more source

FXa‐Responsive Hydrogels to Craft Corneal Endothelial Lamellae

Advanced Healthcare Materials, EarlyView.
This study introduces a sacrificial, multicomponent biohybrid hydrogel system enabling stable scaffold‐free tissue engineering. Its efficacy is demonstrated through the ex vivo development, detachment, and transplantation of human corneal endothelial lamellae, achieving clinically relevant sizes for Descemet Membrane Endothelial Keratoplasty.
Mikhail V. Tsurkan, Juliane Bessert, Rabea Selzer, Sarah D. Tsurkan, Dagmar Pette, Manfred F. Maitz, Petra B. Welzel, Carsten Werner   +7 more
wiley   +1 more source