Results 81 to 90 of about 9,089,625 (306)

Long‐term follow‐up and health‐related quality of life among cancer survivors with stage IEA orbital‐type lymphoma after external photon‐beam radiotherapy: Results from a longitudinal study

open access: yesHematological Oncology, Volume 40, Issue 5, Page 922-929, December 2022., 2022
Abstract We assessed the long‐term outcomes and treatment‐related adverse effects of patients with Stage I, “orbital‐type” lymphomas that were uniformly treated with photons. All consecutive patients diagnosed with low‐grade, Ann Arbor Stage IEA orbital lymphoma treated between 1999 and 2020 at our department were retrospectively reviewed.
Christian Hoffmann   +19 more
wiley   +1 more source

Deep Learning Based Unsupervised and Semi-supervised Classification for Keratoconus [PDF]

open access: yesarXiv, 2020
The transparent cornea is the window of the eye, facilitating the entry of light rays and controlling focusing the movement of the light within the eye. The cornea is critical, contributing to 75% of the refractive power of the eye. Keratoconus is a progressive and multifactorial corneal degenerative disease affecting 1 in 2000 individuals worldwide ...
arxiv  

In vivo Optical Coherence Elastography Reveals Spatial Variation and Anisotropy of Corneal Stiffness [PDF]

open access: yesarXiv, 2023
Objective: The mechanical properties of corneal tissues play a crucial role in determining corneal shape and have significant implications in vision care. This study aimed to address the challenge of obtaining accurate in vivo data for the human cornea.
arxiv  

Involvement of corneal lymphangiogenesis in a mouse model of allergic eye disease.

open access: yesInvestigative Ophthalmology and Visual Science, 2015
PURPOSE The contribution of lymphangiogenesis (LA) to allergy has received considerable attention and therapeutic inhibition of this process via targeting VEGF has been considered.
Hyun-soo Lee   +8 more
semanticscholar   +1 more source

In vivo Terahertz Sensing of Skin Cancer Patients

open access: yesAdvanced Photonics Research, EarlyView.
This study presents the first in vivo measurements of skin cancer patients in a hospital setting using a handheld THz probe. Furthermore, a new analysis approach is developed to generate a patient‐normalized THz response function, which enables clear contrast to be seen between cancer and healthy skin of the same patient.The first in vivo study of skin
Jacob J. Young   +4 more
wiley   +1 more source

Double gene mutations of LRSAM1 and REEP1 and a new REEP1 mutation site found in a patient with amyotrophic lateral sclerosis with subjective paresthesia: A case report

open access: yesIbrain, EarlyView., 2023
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by selective degeneration of upper and lower motor neurons. Leucine‐rich repeats and sterility α mutations in motif 1 (LRSAM1) has been proven to be involved in the pathogenesis of ALS.
Ji‐Yao Qin   +6 more
wiley   +1 more source

Spatially-resolved Brillouin spectroscopy reveals biomechanical changes in early ectatic corneal disease and post-crosslinking in vivo [PDF]

open access: yesarXiv, 2018
Mounting evidence connects the biomechanical properties of tissues to the development of eye diseases such as keratoconus, a common disease in which the cornea thins and bulges into a conical shape. However, measuring biomechanical changes in vivo with sufficient sensitivity for disease detection has proved challenging.
arxiv  

Measuring the visual angle of polarization-related entoptic phenomena using structured light [PDF]

open access: yesarXiv, 2023
The ability to perceive polarization-related entoptic phenomena arises from the dichroism of macular pigments held in Henle's fiber layer of the retina and can be inhibited by retinal diseases such as age-related macular degeneration, which alter the structure of the macula.
arxiv  

A solute gradient in the tear meniscus II. implications for lid margin disease, including meibomian gland dysfunction [PDF]

open access: yes, 2011
We have hypothesized previously that evaporation from the tears generates a solute gradient across the tear meniscus, which delivers hyperosmolar stress to the mucocutaneous junction (MCJ) of the lid margin. This is proposed as the basis for Marx's line,
Bron, A J   +3 more
core   +1 more source

A Silk Fibroin Nanoparticle Hydrogel Loaded With NK1R Antagonist Has Synergistic Anti‐Inflammatory and Reparative Effects on Dry Eye Disease

open access: yesAdvanced Science, EarlyView.
This study develops a silk fibroin (SF) nanoparticles hydrogel targeting neurokinin 1 receptor with CP‐99994 (CP). Combining CP and SF to form stable nanoparticles while incorporating a flexible hydrogel material results in a sustained‐release ophthalmic drop formulation (SF@CP@Gel), which provides a long‐lasting ophthalmic formulation with anti ...
Bo Gong   +12 more
wiley   +1 more source

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