Nanomedicine Approaches for Corneal Diseases [PDF]
Journal of Functional Biomaterials, 2015 Corneal diseases are the third leading cause of blindness globally. Topical nonsteroidal anti-inflammatory drugs (NSAIDs), steroids, antibiotics and tissue transplantation are currently used to treat corneal pathological conditions.
Shyam S. Chaurasia +3 more
doaj +6 more sources
Metabolomics in Corneal Diseases: A Narrative Review from Clinical Aspects [PDF]
Metabolites, 2023 Corneal pathologies may have subtle manifestations in the initial stages, delaying diagnosis and timely treatment. This can lead to irreversible visual loss.
Alvin Wei Jun Teo +3 more
doaj +3 more sources
Corneal Cross-Linking: The Evolution of Treatment for Corneal Diseases. [PDF]
Front Pharmacol, 2021 Corneal cross-linking (CXL) using riboflavin and ultraviolet A (UVA) light has become a useful treatment option for not only corneal ectasias, such as keratoconus, but also a number of other corneal diseases. Riboflavin is a photoactivated chromophore that plays an integral role in facilitating collagen crosslinking.
Wu D +6 more
europepmc +7 more sources
Adeno-Associated Virus Mediated Gene Therapy for Corneal Diseases [PDF]
Pharmaceutics, 2020 According to the World Health Organization, corneal diseases are the fourth leading cause of blindness worldwide accounting for 5.1% of all ocular deficiencies. Current therapies for corneal diseases, which include eye drops, oral medications, corrective
Prabhakar Bastola +3 more
doaj +3 more sources
Mesenchymal Stem Cells and Exosomes: A Novel Therapeutic Approach for Corneal Diseases. [PDF]
Int J Mol Sci, 2023 The cornea, with its delicate structure, is vulnerable to damage from physical, chemical, and genetic factors. Corneal transplantation, including penetrating and lamellar keratoplasties, can restore the functions of the cornea in cases of severe damage ...
Bhujel B +8 more
europepmc +2 more sources
Big data in corneal diseases and cataract: Current applications and future directions. [PDF]
Front Big Data, 2023 The accelerated growth in electronic health records (EHR), Internet-of-Things, mHealth, telemedicine, and artificial intelligence (AI) in the recent years have significantly fuelled the interest and development in big data research.
Ting DSJ, Deshmukh R, Ting DSW, Ang M.
europepmc +2 more sources
Roles and Mechanisms of Regulated Necrosis in Corneal Diseases: Progress and Perspectives. [PDF]
J Ophthalmol, 2022 Regulated necrosis is defined as cell death characterized by loss of the cell membrane integrity and release of the cytoplasmic content. It contributes to the development and progression of some diseases, including ischemic stroke injury, liver diseases,
Lin W, Chen M, Cissé Y, Chen X, Bai L.
europepmc +2 more sources
Deep learning model for extensive smartphone-based diagnosis and triage of cataracts and multiple corneal diseases. [PDF]
Br J OphthalmolAim To develop an artificial intelligence (AI) algorithm that diagnoses cataracts/corneal diseases from multiple conditions using smartphone images. Methods This study included 6442 images that were captured using a slit-lamp microscope (6106 images) and
Ueno Y +14 more
europepmc +2 more sources
Corneal Opacity in LCAT Disease [PDF]
Cornea, 1992 Deficiency of lecithin:cholesterol acyltransferase, LCAT disease, is one of the dyslipoproteinemias with characteristic lipid deposits in the cornea. The present report documents the clinicopathologic abnormalities of one case in which a full-thickness corneal specimen was obtained at the time of corneal transplantation.
David G. Cogan +3 more
openalex +5 more sources
The role of lipids in corneal diseases and dystrophies: a systematic review. [PDF]
Clin Transl Med, 2017 Rowsey TG, Karamichos D.
europepmc +4 more sources