Results 1 to 10 of about 133,903 (210)
Exploiting the Generative Adversarial Network Approach to Create a Synthetic Topography Corneal Image [PDF]
Biomolecules, 2022 Corneal diseases are the most common eye disorders. Deep learning techniques are used to perform automated diagnoses of cornea. Deep learning networks require large-scale annotated datasets, which is conceded as a weakness of deep learning. In this work,
Samer Kais Jameel +6 more
doaj +2 more sources
Corneal Cross-Linking: The Evolution of Treatment for Corneal Diseases. [PDF]
Front Pharmacol, 2021 Corneal cross-linking (CXL) using riboflavin and ultraviolet A (UVA) light has become a useful treatment option for not only corneal ectasias, such as keratoconus, but also a number of other corneal diseases. Riboflavin is a photoactivated chromophore that plays an integral role in facilitating collagen crosslinking.
Wu D +6 more
europepmc +7 more sources
Nrf2, a Potential Therapeutic Target against Oxidative Stress in Corneal Diseases. [PDF]
Oxid Med Cell Longev, 2017 Corneal diseases are one of the major causes of blindness worldwide. Conservative medical agents, which may prevent sight-threatening corneal disease progression, are urgently desired.
Liu XF +10 more
europepmc +4 more sources
Adeno-Associated Virus Mediated Gene Therapy for Corneal Diseases. [PDF]
Pharmaceutics, 2020 According to the World Health Organization, corneal diseases are the fourth leading cause of blindness worldwide accounting for 5.1% of all ocular deficiencies. Current therapies for corneal diseases, which include eye drops, oral medications, corrective
Bastola P, Song L, Gilger BC, Hirsch ML.
europepmc +2 more sources
Nanomedicine approaches for corneal diseases. [PDF]
J Funct Biomater, 2015 Corneal diseases are the third leading cause of blindness globally. Topical nonsteroidal anti-inflammatory drugs (NSAIDs), steroids, antibiotics and tissue transplantation are currently used to treat corneal pathological conditions. However, barrier properties of the ocular surface necessitate high concentration of the drugs applied in the eye ...
Chaurasia SS +3 more
europepmc +5 more sources
Methylation in cornea and corneal diseases: a systematic review. [PDF]
Cell Death DiscovCorneal diseases are among the primary causes of blindness and vision loss worldwide. However, the pathogenesis of corneal diseases remains elusive, and diagnostic and therapeutic tools are limited.
Xia Y +11 more
europepmc +2 more sources
The Role of Rho Kinase Inhibitors in Corneal Diseases. [PDF]
Drug Des Devel TherStefan Futterknecht,1,2 Eleftherios Chatzimichail,1 Konstantin Gugleta,1,3 Georgios D Panos,4,5,* Zisis Gatzioufas1,3,* 1Department of Ophthalmology, University Hospital of Basel, Basel, Switzerland; 2Institute of Molecular and Clinical ...
Futterknecht S +4 more
europepmc +2 more sources
Cell Therapy of Corneal Diseases. [PDF]
Cornea, 2016 Mesenchymal stem cells isolated from connective tissues are pluripotent and differentiate into phenotypes of connective tissue cell lineages (osteoblasts, chondrocytes, and adipocytes) in vitro and in vivo. They have been used to treat mouse models of connective tissue disease such as lumican-null (Lum) and mucopolysaccharidosis (Gusb) mice ...
Kao WW, Coulson-Thomas VJ.
europepmc +4 more sources
Corneal Disease & Transplantation
Journal of Clinical Medicine, 2022 Corneal diseases represent the third leading cause of blindness worldwide, and corneal transplantation, which aims at restoring corneal clarity and vision, is the most frequently performed transplant worldwide [...]
Giulia Coco, Vito Romano
openaire +5 more sources
Cells, 2023 (1) Background: Cell injection therapy is an emerging treatment for bullous keratopathy (BK). Anterior segment optical coherence tomography (AS-OCT) imaging allows the high-resolution assessment of the anterior chamber. Our study aimed to investigate the
Evan N. Wong +7 more
doaj +1 more source