Results 111 to 120 of about 135,941 (356)

Nanotherapy for Neural Retinal Regeneration

Advanced Science, EarlyView.
Nanotechnology enhances ophthalmic treatments by improving drug delivery and regenerating ocular tissues, combating vision loss from retinal diseases through innovative nano‐systems. This review outlines ocular anatomy, pathology, immune microenvironment, and barriers, detailing nanocarrier characteristics, classification, and preparation methods, and ...
Chuyao Yu, Li Dong, Yujia Lv, Xuhan Shi, Ruiheng Zhang, Wenda Zhou, Haotian Wu, Heyan Li, Yitong Li, Zhou Li, Dan Luo, Wen‐Bin Wei   +11 more
wiley   +1 more source

Corneal nerves in health and disease [PDF]

Survey of Ophthalmology, 2014
Corneal nerves are responsible for the sensations of touch, pain, and temperature and play an important role in the blink reflex, wound healing, and tear production and secretion. Corneal nerve dysfunction is a frequent feature of diseases that cause opacities and result in corneal blindness.
May Bakir, Brittany Shaheen, Sandeep Jain   +2 more
openaire   +3 more sources

Microneedles at the Forefront of Next Generation Theranostics

Advanced Science, EarlyView.
The TOC figure illustrates the revolutionary role of microneedles in modern medicine, showcasing their dual diagnostic and therapeutic functions. On the left, microneedles access interstitial fluid for real‐time monitoring of biomarkers like glucose and hormones.
Chan Wang, Yuan Yang, Jiaqi Zhang, Hanrui Zhang, Qian Wang, Shengmei Ma, Pengfei Zhao, Zhou Li, Yuxin Liu   +8 more
wiley   +1 more source

Peptide Amphiphiles in Corneal Tissue Engineering

Journal of Functional Biomaterials, 2015
The increasing interest in effort towards creating alternative therapies have led to exciting breakthroughs in the attempt to bio-fabricate and engineer live tissues.
Martina Miotto, Ricardo M. Gouveia, Che J. Connon   +2 more
doaj   +1 more source

Controlled Release of rAAV Vectors from APMA-Functionalized Contact Lenses for Corneal Gene Therapy

Pharmaceutics, 2020
As an alternative to eye drops and ocular injections for gene therapy, the aim of this work was to design for the first time hydrogel contact lenses that can act as platforms for the controlled delivery of viral vectors (recombinant adeno-associated ...
Fernando Alvarez-Rivera, Ana Rey-Rico, Jagadeesh K Venkatesan, Luis Diaz-Gomez, Magali Cucchiarini, Angel Concheiro, Carmen Alvarez-Lorenzo   +6 more
doaj   +1 more source

Identifying factors associated with fast visual field progression in patients with ocular hypertension based on unsupervised machine learning [PDF]

arXiv, 2023
Purpose: To identify ocular hypertension (OHT) subtypes with different trends of visual field (VF) progression based on unsupervised machine learning and to discover factors associated with fast VF progression. Participants: A total of 3133 eyes of 1568 ocular hypertension treatment study (OHTS) participants with at least five follow-up VF tests were ...
arxiv  

Delivery of Human iPSC‐Derived RPE Cells in Healthy Minipig Retina Results in Interaction Between Photoreceptors and Transplanted Cells

Advanced Science, EarlyView.
Human induced pluripotent stem cell‐derived retinal pigment epithelial (hiPSC‐RPE) cells, cultured on a clinically relevant PDLLA scaffold, are transplanted into immunosuppressed minipigs. The study demonstrates the viability, integration, and preservation of RPE‐specific features without gliosis or neuroinflammation, supporting their potential as a ...
Anna Macečková Brymová, Francisco Javier Rodriguez‐Jimenez, Annika Konrad, Yaroslav Nemesh, Muhammed Arshad Thottappali, Ana Artero‐Castro, Ruslan Nyshchuk, Anastasiia Kolesnikova, Brigitte Müller, Hana Studenovska, Jana Juhasova, Stefan Juhas, Ivona Valekova, Dunja Lukovic, Claudia Aleman, Taras Ardan, Saskia Drutovič, Jan Motlik, Zdenka Ellederova, Zbinek Straňák, Miroslav Veith, Lyubomyr Lytvynchuk, Ruchi Sharma, Kapil Bharti, Goran Petrovski, Pavla Jendelova, Knut Stieger, Slaven Erceg   +27 more
wiley   +1 more source

Causes of congenital corneal opacities and their management in a tertiary care center. [PDF]

, 2020
PURPOSE: To evaluate causes and management of congenital corneal opacities (CCO) diagnosed in a tertiary care eye center and to compare the data with a previous study at the same institution.
Hammersmith, Kristin M, Karadag, Remzi, Nagra, Parveen K, Rapuano, Christopher J   +3 more
core   +1 more source

A Tailored Hydrogel With Local Glycemia Management, Antioxidant Activity, and Photothermal Antibacterial Properties for Diabetic Wound Healing

Advanced Science, EarlyView.
A multifunctional wound dressing (ACG gels) with antioxidant, local glycocontrol, and antibacterial properties to promote diabetic wound healing. Au‐CeO2 dumbbells effectively eliminate ROS, protecting cells from oxidative stress‐induced damage while exhibiting significant near‐infrared photothermal antibacterial activity.
Bangguo Zhou, Yangying Duan, Wenhao Li, Tao Chen, Jincheng Wang, Manting Cao, Guohao Lin, Ke Yang, Zhangqi Lai, Wencheng Wu   +9 more
wiley   +1 more source

Ocular manifestations of psoriasis: An inflammatory disease beyond the skin

Journal of General and Family Medicine, Volume 24, Issue 1, Page 45-49, January 2023., 2023
Psoriasis can lead to meibomian gland dysfunction, especially in patients with long‐lasting disease. Hence, dermatologists and general practitioners should be vigilant in this regard when visiting psoriasis patients, especially those who have higher PASI values or long‐lasting disease.
Zeinab Aryanian, Azar Shirzadian, Parvaneh Hatami, Gholam abbas Roostayi, Sadrollah Najafi, Azadeh Goodarzi   +5 more
wiley   +1 more source