Deep learning model for extensive smartphone-based diagnosis and triage of cataracts and multiple corneal diseases. [PDF]
Aim To develop an artificial intelligence (AI) algorithm that diagnoses cataracts/corneal diseases from multiple conditions using smartphone images. Methods This study included 6442 images that were captured using a slit-lamp microscope (6106 images) and
Ueno Y+14 more
europepmc +2 more sources
Corneal Opacity in LCAT Disease [PDF]
Deficiency of lecithin:cholesterol acyltransferase, LCAT disease, is one of the dyslipoproteinemias with characteristic lipid deposits in the cornea. The present report documents the clinicopathologic abnormalities of one case in which a full-thickness corneal specimen was obtained at the time of corneal transplantation.
David G. Cogan+3 more
openalex +5 more sources
The Role of Rho Kinase Inhibitors in Corneal Diseases. [PDF]
The cornea, as the outermost layer of the eye, plays a crucial role in vision by focusing light onto the retina. Various diseases and injuries can compromise its clarity, leading to impaired vision.
Futterknecht S+4 more
europepmc +2 more sources
Deep learning for identifying corneal diseases from ocular surface slit-lamp photographs. [PDF]
To demonstrate the identification of corneal diseases using a novel deep learning algorithm. A novel hierarchical deep learning network, which is composed of a family of multi-task multi-label learning classifiers representing different levels of eye ...
Gu H+10 more
europepmc +2 more sources
Adeno-Associated Virus Mediated Gene Therapy for Corneal Diseases. [PDF]
According to the World Health Organization, corneal diseases are the fourth leading cause of blindness worldwide accounting for 5.1% of all ocular deficiencies. Current therapies for corneal diseases, which include eye drops, oral medications, corrective
Bastola P, Song L, Gilger BC, Hirsch ML.
europepmc +2 more sources
Visual rehabilitation of patients with corneal diseases. [PDF]
Background Although most patients with visual impairment due to corneal diseases can be treated successfully with surgery, some require visual rehabilitation to restore reading ability.
Oeverhaus M+5 more
europepmc +2 more sources
Diseases of the corneal endothelium.
The corneal endothelial monolayer and associated Descemet's membrane (DM) complex is a unique structure that plays an essential role in corneal function. Endothelial cells are neural crest derived cells that rest on a special extracellular matrix and play a major role in maintaining stromal hydration within a narrow physiologic range necessary for ...
Lauren J. Jeang, C. Margo, E. Espana
semanticscholar +3 more sources
Current Trends and Future Perspective of Mesenchymal Stem Cells and Exosomes in Corneal Diseases. [PDF]
The corneal functions (transparency, refractivity and mechanical strength) deteriorate in many corneal diseases but can be restored after corneal transplantation (penetrating and lamellar keratoplasties).
Mansoor H+5 more
europepmc +2 more sources
Optical coherence tomography for ocular surface and corneal diseases: a review. [PDF]
The advent of optical coherence tomography (OCT) imaging has changed the way ophthalmologists image the ocular surface and anterior segment of the eye.
Venkateswaran N+3 more
europepmc +2 more sources
Nrf2, a Potential Therapeutic Target against Oxidative Stress in Corneal Diseases. [PDF]
Corneal diseases are one of the major causes of blindness worldwide. Conservative medical agents, which may prevent sight-threatening corneal disease progression, are urgently desired.
Liu XF+10 more
europepmc +2 more sources