Effect of recombinant human nerve growth factor eye drops in patients with dry eye: a phase IIa, open label, multiple-dose study [PDF]
Background: Dry eye disease (DED) affects more than 14% of the elderly population causing decrease of quality of life, high costs and vision impairment.
Allegretti, M.+7 more
core +1 more source
Awareness regarding eye donation among stakeholders in Srikakulam district in South India [PDF]
Background There is a huge need for the availability of transplantable donor corneas worldwide to reduce the burden of corneal blindness due to corneal opacity.
Jalbert, I.+3 more
core +4 more sources
Diagnosis and management of iridocorneal endothelial syndrome [PDF]
The iridocorneal endothelial (ICE) syndrome is a rare ocular disorder that includes a group of conditions characterized by structural and proliferative abnormalities of the corneal endothelium, the anterior chamber angle, and the iris.
Ambrosio, Oriella+5 more
core +2 more sources
Intracameral lidocaine as supplement to classic topical anesthesia for relieving ocular pain in cataract surgery [PDF]
● AIM: To evaluate safety, efficacy, and patient adherence of intracameral lidocaine as supplement of classic topical anesthetic drops in cataract surgery.
Librando, Aloisa+4 more
core +2 more sources
Poly-l/dl-lactic acid films functionalized with collagen IV as carrier substrata for corneal epithelial stem cells [PDF]
Limbal epithelial stem cells (LESCs) are responsible for the renewal of corneal epithelium. Cultivated limbal epithelial transplantation is the current treatment of choice for restoring the loss or dysfunction of LESCs.
Calonge Cano, Margarita+7 more
core +3 more sources
LAMELAR CORNEAL TRANSPLANTATION IN A DOG FOR SURGICAL TREATMENT OF CORNEA DEEP ULCER WITH DESCEMETOCELE. [PDF]
Corneal transplantation is a procedure indicated for surgical treatment of several corneal diseases, requiring replacement of the affected tissues1,2,3,4.
Alexandre, N.+3 more
core
Tear ferning test and pathological effects on ocular surface before and after topical cyclosporine in vernal keratoconjunctivitis patients [PDF]
Background: Vernal keratoconjunctivitis (VKC) is a rare ocular surface inflammatory disease that affects mainly boys in the first decade of life.
Bianchi, Guia+6 more
core +1 more source
Understanding and measuring mechanical signals in the tumor stroma
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz+3 more
wiley +1 more source
The variability of corneal and anterior segment parameters in keratoconus [PDF]
Purpose: To analyse, describe and test diverse corneal and anterior segment parameters in normal and keratoconic eyes to better understand the geometry of the keratoconic cornea. Method: 44 eyes from 44 keratoconic patients and 44 eyes from 44 healthy
Cardona Torradeflot, Genís+3 more
core +1 more source
Therapeutic Contact Lenses in the Treatment of Corneal and Ocular Surface Diseases-A Review.
Therapeutic contact lenses (TCLs) are often used in the management of a wide variety of corneal and ocular surface diseases (OSDs). Indications of TCL include pain relief, enhancing corneal healing, corneal sealing, corneal protection, and drug delivery.
L. Lim, Elizabeth Wen Ling Lim
semanticscholar +1 more source