Results 61 to 70 of about 2,181,842 (257)

Arginine depletion as a mechanism for the immune privilege of corneal allografts. [PDF]

, 2011
The cornea is an immune privileged tissue. Since arginase has been found to modulate T-cell function by depleting arginine, we investigated the expression of arginase in the cornea and its possible role in immune privilege using a murine transplant model.
Larkin, Daniel FP, George, Andrew J.T., Fu, Hongmei, Coe, D, Hongmei Fu, Chai, J-G, Zaher, S, David Coe, George, Andrew JT, Fu, H, Khan, A, Larkin, Daniel F.P., Jian-Guo Chai, Ingrid Müller, Kropf, P, Müller, Ingrid, Kropf, Pascale, Larkin, DFP, George, AJT, Adnan Khan, Khan, Adnan, Zaher, Sarah, Daniel F. P. Larkin, Mueller, I, Pascale Kropf, Coe, David, Sarah Zaher, Andrew J. T. George, Chai, Jian-Guo   +28 more
core   +1 more source

A study exploring the causal relationship between glaucoma and anxiety disorders

Frontiers in Medicine
BackgroundGlaucoma, a leading cause of global blindness, is characterized by optic nerve damage and visual field loss. Previous studies have suggested a potential association between glaucoma and anxiety disorders.
Bin Lin, Bin Lin, Bin Lin, Bin Lin, Bin Lin, Bin Lin, Meng Xu, Meng Xu, Meng Xu, Meng Xu, Meng Xu, Meng Xu, Long-long Chen, Long-long Chen, Long-long Chen, Long-long Chen, Long-long Chen, Long-long Chen, Dong-kan Li, Dong-kan Li, Dong-kan Li, Dong-kan Li, Dong-kan Li, Dong-kan Li   +23 more
doaj   +1 more source

Tumbling Magnetic Microrobots for Targeted In Vivo Drug Delivery in the GI Tract

Advanced Robotics Research, EarlyView.
We introduce a microrobot design and integrated system for on‐demand targeted drug release in the gastrointestinal tract. The microrobot has an embedded magnet for actuation with external magnetic fields and is visualized in real time using ultrasound. It has two drug release ports sealed with a thermally sensitive wax. Local heating of the wax using a
Aaron C. Davis, Luis Carlos Sanjuan Acosta, Shubh P. Mehta, Baiyan Qi, Yang Yang, Luis Solorio, Craig J. Goergen, David J. Cappelleri   +7 more
wiley   +1 more source

Efficacy and visual outcomes of the foldable capsular buckle scleral buckling in rhegmatogenous retinal detachment

Frontiers in Medicine
ObjectiveTo investigate the difference in the effectiveness and refraction of the foldable capsular buckle (FCB) in rhegmatogenous retinal detachment (RRD).MethodsSix patients with simple RRD were treated for FCB scleral buckling at Xiamen Eye Center of ...
Guohua Jiang, Guohua Jiang, Guohua Jiang, Guohua Jiang, Guohua Jiang, Guohua Jiang, Yuan Lin, Yuan Lin, Yuan Lin, Yuan Lin, Yuan Lin, Yuan Lin, Yan Chen, Yan Chen, Yan Chen, Yan Chen, Yan Chen, Yan Chen, Huping Wu, Huping Wu, Huping Wu, Huping Wu, Huping Wu, Huping Wu   +23 more
doaj   +1 more source

Exploiting the Generative Adversarial Network Approach to Create a Synthetic Topography Corneal Image

Biomolecules, 2022
Corneal diseases are the most common eye disorders. Deep learning techniques are used to perform automated diagnoses of cornea. Deep learning networks require large-scale annotated datasets, which is conceded as a weakness of deep learning. In this work,
Samer Kais Jameel, Sezgin Aydin, Nebras H. Ghaeb, Jafar Majidpour, Tarik A. Rashid, Sinan Q. Salih, Poh Soon JosephNg   +6 more
doaj   +1 more source

A Whole‐Head Finite Element Model for Electrical Neuromodulation via Visual Brain‐Machine Interfaces

Advanced Science, EarlyView.
A multimodal, personalized head model is presented that integrates the entire visual pathway with surrounding tissues to simulate electrical stimulation of the optic nerve. In vivo validation in humans and goats, plus systematic component‐elimination analysis, demonstrates the high accuracy of the comprehensive model.
Shengjian Lu, Tonghe Yang, Yuan Geng, Huan Wu, Yangrui Huang, Te Zheng, Haodi Chen, Shurui Huang, Yi Cao, Jian Yang, Wentao Yan, Yikui Zhang, Wencan Wu   +12 more
wiley   +1 more source

Imaging-based assessment of corneal graft rejection after penetrating keratoplasty: insights from confocal microscopy and anterior chamber analysis

Frontiers in Medicine
ObjectiveThis study aimed to explore the distribution of rejection and visual changes after optical and therapeutic penetrating keratoplasty (PKP) in Southeastern China.MethodsThis retrospective study included 104 patients who underwent either optical or
Yuan Lin, Yuan Lin, Yuan Lin, Yuan Lin, Yuan Lin, Yuan Lin, Miaomiao Liu, Miaomiao Liu, Miaomiao Liu, Miaomiao Liu, Miaomiao Liu, Miaomiao Liu, Hanqiao Li, Hanqiao Li, Hanqiao Li, Hanqiao Li, Hanqiao Li, Hanqiao Li, Xie Fang, Xie Fang, Xie Fang, Xie Fang, Xie Fang, Xie Fang, Zhiwen Xie, Zhiwen Xie, Zhiwen Xie, Zhiwen Xie, Zhiwen Xie, Zhiwen Xie, Shunrong Luo, Shunrong Luo, Shunrong Luo, Shunrong Luo, Shunrong Luo, Shunrong Luo, Xianwen Xiao, Xianwen Xiao, Xianwen Xiao, Xianwen Xiao, Xianwen Xiao, Xianwen Xiao, Huping Wu, Huping Wu, Huping Wu, Huping Wu, Huping Wu, Huping Wu   +47 more
doaj   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Case Report: IVCM of corneal chlorpromazine toxicity drug deposits

Frontiers in Medicine
To investigate corneal deposits in a patient undergoing long-term chlorpromazine therapy using in vivo confocal microscopy with the HRT II Rostock Corneal Module.
Xianwen Xiao, Xianwen Xiao, Xianwen Xiao, Xianwen Xiao, Xianwen Xiao, Xianwen Xiao, Xie Fang, Xie Fang, Xie Fang, Xie Fang, Xie Fang, Xie Fang, Zhiwen Xie, Zhiwen Xie, Zhiwen Xie, Zhiwen Xie, Zhiwen Xie, Zhiwen Xie, Shunrong Luo, Shunrong Luo, Shunrong Luo, Shunrong Luo, Shunrong Luo, Shunrong Luo, Yuan Lin, Yuan Lin, Yuan Lin, Yuan Lin, Yuan Lin, Yuan Lin, Huping Wu, Huping Wu, Huping Wu, Huping Wu, Huping Wu, Huping Wu   +35 more
doaj   +1 more source

Chiral Nanoparticles Suppress Inflammatory Infiltration to Promote Extracellular Matrix Remodeling for Ectopia Lentis Therapy

Advanced Science, EarlyView.
L‐cysteine‐configured chiral polyurethane nanoparticles suppress ocular inflammation and reduce extracellular matrix (ECM) degradation in ectopia lentis by regulating macrophages polarization and inhibiting nuclear factor kappa B signaling pathway. By promoting zonular fiber‐associated protein restoration and tissue repair, this minimally invasive ...
Yinuo Wen, Yan Yang, Haihan Gao, Yan Liu, Xinyue Wang, Linghao Song, Ruohong Li, Ao Miao, Jie Xu, Zhennan Zhao, Dan Li, Shenjie Peng, Linzhao Li, Min Zhang, Yonghang Liu, Liren Wang, Tianhui Chen, Yongxiang Jiang   +17 more
wiley   +1 more source