Results 81 to 90 of about 135,122 (302)

Demography and disorders of the French Bulldog population under primary veterinary care in the UK in 2013 [PDF]

, 2018
Background Despite its Gallic name, the French Bulldog is a breed of both British and French origin that was first recognised by The Kennel Club in 1906. The French Bulldog has demonstrated recent rapid rises in Kennel Club registrations and is now (2017)
A Agresti, A Gough, BL Hart, BM Wiles, BR Kirkwood, DG O'Neill, DG O'Neill, DG O'Neill, DG O'Neill, DG O'Neill, DG O'Neill, DG O'Neill, DG O’Neill, DG O’Neill, DG O’Neill, DG O’Neill, F Picco, FD McMillan, FS Roedler, H Herzog, J Perez-Guisado, KT Teng, MCCM Inglez de Souza, N Pearce, N-C Liu, NJ Beausoleil, P Bateson, P Sandøe, R Ryan, RMA Packer, RMA Packer, RMA Packer, S Ghirlanda, S Ghirlanda, S Wilhem, T Nuttall, V Mayousse   +36 more
core   +2 more sources

A Circuit of Mechanically Regulated Transcription Factors Balances Regenerative and Fibrotic Memory of Mesenchymal Stromal Cells

Advanced Science, EarlyView.
Producing MSCs on rigid culture substrates induces a scar‐making phenotype, jeapordizing therapeutic success. ‘Tissue‐soft’ surfaces prevent MSC fibrogenesis and preserve regenerative traits. An epigenetic network, driven by HOXA11 and SALL1, maintains ‘soft memory’ by keeping chromatin open in relaxed MSCs, promoting anti‐fibrotic programs.
Fereshteh Sadat Younesi, Andrew E. Miller, Li Diao, Xinying Guo, Natalie Andonian, Elham Karimizadeh, Thomas H. Barker, Boris Hinz   +7 more
wiley   +1 more source

Visual outcomes and spectacle independence of a non-diffractive wavefront-shaping intraocular lens in post-LASIK patients

Frontiers in Medicine
PurposeTo compare visual outcomes, depth of field (DOF), spectacle independence, and patient satisfaction of cataract patients with and without previous myopic laser in situ keratomileusis (LASIK) surgery who received a non-diffractive extended range-of ...
Wei Fan, Wei Fan, Wei Fan, Wei Fan, Wei Fan, Wei Fan, Meiyi Zhu, Meiyi Zhu, Meiyi Zhu, Meiyi Zhu, Meiyi Zhu, Meiyi Zhu, Guangbin Zhang, Guangbin Zhang, Guangbin Zhang, Guangbin Zhang, Guangbin Zhang, Guangbin Zhang   +17 more
doaj   +1 more source

Human Microsporidial Infections [PDF]

, 2006
Microsporidia are eukaryotic, spore forming obligate intracellular parasites, first recognised over 100 years ago. Microsporidia are becoming increasingly recognised as infectious pathogens causing intestinal and extra-intestinal diseases in both immuno ...
D D, Duhlinska, G I, Anyanwu, I CJ, Omalu, P U, Inyama, V A, Pam   +4 more
core  

Management of anterior chamber dislocation of a dexamethasone intravitreal implant: a case report [PDF]

, 2016
Background Ozurdex is a 700 mcg dexamethasone intravitreal implant, approved for the management of macular edema secondary to retinal vein occlusion, and other related pathoglogiesAnterior chamber dislocation of Ozurdex represents an uncommon ...
AGOSTINELLI, Enzo, CARLESIMO, Sandra Cinzia, Forastiere, Michele, NEBBIOSO, Marcella, PACELLA, Elena, PACELLA, FERNANDA, SECONDI, ROBERTO   +6 more
core   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Insights and decision-making on surgical triggers of glaucoma-related complications in congenital cataract surgery: a clinical review

Frontiers in Medicine
Glaucoma-related adverse events (GRAE) after congenital cataract surgery severely affect the visual recovery of children and have attracted significant attention in the medical community. This article focuses on the research of its surgical factors.
Bin Lin, Bin Lin, Bin Lin, Bin Lin, Bin Lin, Bin Lin, Wei Fan, Wei Fan, Wei Fan, Wei Fan, Wei Fan, Wei Fan, Dong-kan Li, Dong-kan Li, Dong-kan Li, Dong-kan Li, Dong-kan Li, Dong-kan Li   +17 more
doaj   +1 more source

Overexpression of MMPs in Corneas Requiring Penetrating and Deep Anterior Lamellar Keratoplasty. [PDF]

, 2019
PurposeMatrix metalloproteinases (MMPs) comprise a family of zinc-dependent endopeptidases involved in wound healing processes, including neovascularization and fibrosis. We assessed MMP protein expression levels in diseased corneas of patients requiring
Chan, Matilda F, Clay, Selene M, Hwang, David G, Oldenburg, Catherine E, Rose-Nussbaumer, Jennifer, Wolf, Marie   +5 more
core  

Highly Biomimetic Ectodermal Epithelial Organoids for Epithelial Barrier Stimulation Assays

Advanced Science, EarlyView.
ABSTRACT Evaluating the potential toxicity of pharmaceuticals and biomaterials to ectodermal epithelia, such as the oral mucosa and skin, is indispensable in pre‐clinical assessments. However, this remains a challenge primarily owing to the lack of physiologically relevant and accurate screening models.
Yiming Chen, Yuman Li, Chenyu Deng, Leran Li, Zhewen Hu, Boon Chin Heng, Yuting Niu, Shiyu Sun, Min Gao, Xiaopei Chi, Ying He, Mingming Xu, Ying Huang, Xuliang Deng   +13 more
wiley   +1 more source

Intravitreal drug injection for glaucoma: mechanisms, clinical efficacy, and future horizons

Frontiers in Pharmacology
Intravitreal drug injection has emerged as a transformative approach in glaucoma management, overcoming the limitations of traditional treatments such as poor compliance with topical medications and high complication rates of filtration surgery.
Bin Lin, Bin Lin, Bin Lin, Bin Lin, Bin Lin, Bin Lin, Peng Shi, Peng Shi, Peng Shi, Peng Shi, Peng Shi, Peng Shi, Dong-Kan Li, Dong-Kan Li, Dong-Kan Li, Dong-Kan Li, Dong-Kan Li, Dong-Kan Li   +17 more
doaj   +1 more source