Results 71 to 80 of about 135,122 (302)

Epidemiology and tumor microenvironment of ocular surface and orbital tumors on growth and malignant transformation

Frontiers in Oncology
The ocular surface and orbit constitute unique microenvironments in the human body. Current advances in molecular research have deepened our understanding of tumor development in these regions.
Shangkun Ou, Shangkun Ou, Shangkun Ou, Shangkun Ou, Shangkun Ou, Shangkun Ou, Yuan Lin, Yuan Lin, Yuan Lin, Yuan Lin, Yuan Lin, Yuan Lin, Yujie Zhang, Yujie Zhang, Yujie Zhang, Yujie Zhang, Yujie Zhang, Yujie Zhang, Ke Shi, Ke Shi, Ke Shi, Ke Shi, Ke Shi, Ke Shi, Huping Wu, Huping Wu, Huping Wu, Huping Wu, Huping Wu, Huping Wu   +29 more
doaj   +1 more source

Novel application assigned to toluquinol: inhibition of lymphangiogenesis by interfering with VEGF-C/VEGFR-3 signalling pathway [PDF]

, 2016
BACKGROUND AND PURPOSE Lymphangiogenesis is an important biological process associated with the pathogenesis of several diseases, including metastatic dissemination, graft rejection, lymphoedema and other inflammatory disorders.
Blacher, S., García-Caballero, Melissa, Medina, Miguel Ángel, Nöel, Agnes, Pauper, J., Quesada, Ana R.   +5 more
core  

Blindness incidence in Germany - A population-based study from Württemberg-Hohenzollern [PDF]

, 1999
Few data on the incidence of blindness in Germany are available. We analysed causes of legal blindness for the region Württemberg-Hohenzollern (population 5.5 million) in order to help fill in this gap.
Klauss, V., Krumpaszky, H. G., Lüdtke, R., Mickler, A., Selbmann, H. K.   +4 more
core   +1 more source

N, S Co‐Doped Carbon Quantum Dots‐Riboflavin Composite Photosensitizers for Enhanced Iontophoresis‐Assisted Corneal Cross‐Linking

Advanced Science, EarlyView.
This study explores the use of N, S co‐doped carbon quantum dots (NS‐CQDs) as carriers for riboflavin, creating NS‐CQDs‐RF composite photosensitizers. These composites improve riboflavin absorption, enhance ROS generation efficiency, and preserve corneal epithelium integrity.
Tinghong Xu, Yong Liu, Wenjing Zhang, Qiuruo Jiang, Yi Jin, Liangzheng Lin, Lumeng Wang, Zhanhao Gu, Mimi Lin, Shihao Chen   +9 more
wiley   +1 more source

Greening vision: balancing clinical excellence and ecological sustainability in eye health

Frontiers in Public Health
The rapid advancement of ophthalmic medicine has significantly improved global visual health but concurrently imposed substantial ecological costs, creating an environmental paradox between efficient treatment and sustainability. This review explores the
Bin Lin, Bin Lin, Bin Lin, Bin Lin, Bin Lin, Bin Lin, Jing Tang, Wei Liang, Wei Liang, Wei Liang, Wei Liang, Wei Liang, Wei Liang, Peng Shi, Peng Shi, Peng Shi, Peng Shi, Peng Shi, Peng Shi, Dong-kan Li, Dong-kan Li, Dong-kan Li, Dong-kan Li, Dong-kan Li, Dong-kan Li   +24 more
doaj   +1 more source

Poly-l/dl-lactic acid films functionalized with collagen IV as carrier substrata for corneal epithelial stem cells [PDF]

, 2019
Limbal epithelial stem cells (LESCs) are responsible for the renewal of corneal epithelium. Cultivated limbal epithelial transplantation is the current treatment of choice for restoring the loss or dysfunction of LESCs.
Calonge Cano, Margarita, Engel, Elisabeth, Galindo de la Rosa, Sara, López Paniagua, Marina, Mata Sampedro, Ana de la, Mateos Timoneda, Miguel Ángel, Nieto Miguel, Teresa, Planell, Josep A.   +7 more
core   +3 more sources

A Nanoparticle‐Integrated Complete Manufacturing Pipeline of Chemically Engineered Exosomes

Advanced Science, EarlyView.
We report a novel manufacture technology of chemically engineered exosomes. The four steps of manufacturing, i.e., biogenesis, loading, isolation, and storage, are integrated by the use of a nanoparticle. The manufacture technology incorporates three innovative components, i.e., a new nano‐bio effect, a new composite nanoparticle, and a new isolation ...
Xiaowei Wen, Zixing Xu, Zerun Hao, Yanming Chen, Kai Xie, Haofan Yin, Xueying Wang, Jie Min, Sihan Sun, Baiding Chen, Chengxiu Ling, Mingming Xu, Yizhao Chen, Gang Ruan   +13 more
wiley   +1 more source

Pulsed synchrony regulation of intraocular and cerebrospinal fluid pressure: a novel paradigm for glaucoma pathogenesis and treatment

Frontiers in Medicine
Glaucoma, the leading cause of irreversible blindness worldwide, is characterized by the progressive loss of retinal ganglion cells (RGCs) and their axons.
Bin Lin, Bin Lin, Bin Lin, Bin Lin, Bin Lin, Bin Lin, Duan-Qing Huang, Duan-Qing Huang, Duan-Qing Huang, Duan-Qing Huang, Duan-Qing Huang, Duan-Qing Huang, Ting-Ting Li, Ting-Ting Li, Ting-Ting Li, Ting-Ting Li, Ting-Ting Li, Ting-Ting Li, Wei Liang, Wei Liang, Wei Liang, Wei Liang, Wei Liang, Wei Liang, Meng Xu, Meng Xu, Meng Xu, Meng Xu, Meng Xu, Meng Xu, Dong-Kan Li, Dong-Kan Li, Dong-Kan Li, Dong-Kan Li, Dong-Kan Li, Dong-Kan Li   +35 more
doaj   +1 more source

PVNCRF Neurons Regulate Migraine‐Like Allodynia by Activating CRFR2 on Spinal Trigeminal Caudalis Glutamatergic Neurons

Advanced Science, EarlyView.
Paraventricular CRF neurons in the hypothalamus project to glutamatergic neurons of the spinal trigeminal caudal nucleus, enhancing neuronal activation and CRFR2 signaling. This pathway increases CRF release and excitatory drive, promoting central sensitization and migraine‐related behaviors. Targeting the PVN–SP5C circuit provides a potential strategy
Jiang Bian, Xiao‐Long Wang, Li Yin, Wei Wei, Xue Li, Yao Ge, Zhao‐Xia Xiang, Na Tian, Li‐Juan Chen, Ming‐Wei Ma, Xia Zhang, Xu Jing, Mei‐Yun Wang, Xu‐Feng Xu   +13 more
wiley   +1 more source

Myo-inflam: a mini review on inflammatory pathways driving scleral remodeling and axial elongation

Frontiers in Immunology
Myopia has become a global public health challenge, with pathological high myopia leading to irreversible visual impairment. Accumulating evidence suggests that chronic inflammation is closely associated with scleral remodeling and axial elongation, the ...
Bin Lin, Bin Lin, Bin Lin, Bin Lin, Bin Lin, Bin Lin, Wei Liang, Wei Liang, Wei Liang, Wei Liang, Wei Liang, Wei Liang, Li-rong Cai, Li-rong Cai, Li-rong Cai, Li-rong Cai, Li-rong Cai, Li-rong Cai, Meng Xu, Meng Xu, Meng Xu, Meng Xu, Meng Xu, Meng Xu, Dong-kan Li, Dong-kan Li, Dong-kan Li, Dong-kan Li, Dong-kan Li, Dong-kan Li   +29 more
doaj   +1 more source