Results 61 to 70 of about 132,451 (332)

Precise Quantification of Angiogenesis in 3D Biomaterials Using in Vitro CAM Models: Enhancing 3Rs in Research and Minimizing in Vivo Dependency

open access: yesAdvanced Functional Materials, EarlyView.
The study develops elastin–fibrin scaffolds and evaluates angiogenesis using the chorioallantoic membrane (CAM) model. Advanced imaging with confocal microscopy and Indocyanine Green dye enables precise 3D quantification of vascular networks. Findings demonstrate superior microvessel visualization compared to micro‐CT using Microfil and Optiray 350 ...
Ece Melis Er   +8 more
wiley   +1 more source

Tear IgE point-of-care testing for differentiating type I and type IV allergic conjunctivitis

open access: yesFrontiers in Medicine
ObjectiveThis study aimed to evaluate the diagnostic utility of point-of-care tear immunoglobulin E (IgE) testing in distinguishing between type I and type IV allergic conjunctivitis (AC), and to explore tailored treatment strategies.MethodsA total of ...
Xumin Shang   +65 more
doaj   +1 more source

Ocular-Surface Regeneration Therapies for Eye Disorders: The State of the Art

open access: yesBioTech, 2023
The ocular surface is a complex structure that includes cornea, conjunctiva, limbus, and tear film, and is critical for maintaining visual function. When the ocular-surface integrity is altered by a disease, conventional therapies usually rely on topical
Matteo Posarelli   +7 more
doaj   +1 more source

Tear ferning test and pathological effects on ocular surface before and after topical cyclosporine in vernal keratoconjunctivitis patients [PDF]

open access: yes, 2018
Background: Vernal keratoconjunctivitis (VKC) is a rare ocular surface inflammatory disease that affects mainly boys in the first decade of life.
Bianchi, Guia   +6 more
core   +1 more source

FeDSNP‐Pa Nanoassemblies: A Triple‐Action Therapeutic Strategy Targeting Oxidative Stress, Inflammation, and Pyroptosis for Retinal Ganglion Cell Protection in Glaucoma

open access: yesAdvanced Functional Materials, EarlyView.
FeDSNP‐Pa, a metallized nanoparticle loaded with sodium pyruvate (Pa), exerts triple therapeutic effects by scavenging reactive oxygen species (ROS), suppressing inflammatory responses, and inhibiting pyroptosis signaling pathways. This multifunctional neuroprotective strategy protecting retinal ganglion cells (RGCs) from elevated intraocular pressure ...
Yukun Wu   +5 more
wiley   +1 more source

Systematic inflammatory indicators and clinical management of exogenous endophthalmitis due to metal penetrating injury of eyeball

open access: yesFrontiers in Medicine
ObjectiveTo evaluate systemic inflammatory markers in cases of exogenous endophthalmitis caused by metal foreign bodies after penetrating eye injury and identify risk factors for poor control post-initial emergency surgery.MethodsTwenty-nine patients ...
Donghai Wu   +23 more
doaj   +1 more source

Potential benefits and risks of clinical xenotransplantation [PDF]

open access: yes, 2012
The transplantation of organs and cells from pigs into humans could overcome the critical and continuing problem of the lack of availability of deceased human organs and cells for clinical transplantation.
Ayares, D, Cooper, DKC
core   +2 more sources

Selective Laser Sintering 3D Printing of Drug‐Loaded Intravitreal Implants

open access: yesAdvanced Functional Materials, EarlyView.
Selective laser sintering enables the fabrication of biodegradable and biocompatible intravitreal implants with tunable microstructures for sustained drug delivery. By modulating laser scanning speed, the polymer matrix architecture is engineered to control the release kinetics of dexamethasone and riboflavin over several months. This approach offers a
Iria Seoane‐Viaño   +5 more
wiley   +1 more source

FEVR combined with macular heterotopia in children presenting as pseudo-exotropia: a case report and literature review

open access: yesFrontiers in Medicine
Familial exudative retinopathy (FEVR) is a hereditary disease involving abnormal retinal vascular development in which macular heterotopia (MH) caused by mechanical-like pulling of the vitreous may lead to pseudo-strabismus.
Yujie Zhang   +17 more
doaj   +1 more source

The Application and Research Progress of Artificial Intelligence in Corneal Related Diseases

open access: yesXiehe Yixue Zazhi, 2021
Artificial intelligence(AI)is the frontier of computer science. In recent years, AI has developed rapidly in many fields, and its research in ophthalmology is also increasing.
DI Yu, LI Ying
doaj   +1 more source

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