Results 21 to 30 of about 5,486 (209)

Laser refractive surgery in corneal dystrophies [PDF]

, 2021
Twenty-eight case reports and case series published between 2000 and 2019 concerning laser refractive surgery in patients with corneal dystrophies, resulting in 173 eyes from 94 patients, were included in this systematic review.
Rahul Rachwani-Anil, Carlos Rocha-de-Lossada, José-María Sánchez-González, Sánchez González, José María, Davide Borroni, Rocha de Lossada, Carlos, Colmenero Reina, Elvira, Borroni, Davide, Elvira Colmenero-Reina, Rachwani-Anil, Rahul   +9 more
core   +1 more source

Uncovering the profile of mutations of transforming growth factor beta-induced gene in Chinese corneal dystrophy patients [PDF]

International Journal of Ophthalmology, 2016
AIM: To uncover the mutations profile of transforming growth factor beta-induced (TGFBI) gene in Chinese corneal dystrophy patients and further investigate the characteristics of genotype-phenotype correlations.
Xiao-Dan Hao, Yang-Yang Zhang, Peng Chen, Su-Xia Li, Ye Wang   +4 more
doaj   +1 more source

Update on the genetics of corneal endothelial dystrophies

Indian Journal of Ophthalmology, 2022
Corneal endothelial dystrophies are a heterogeneous group of diseases with different modes of inheritance and genetic basis for each dystrophy. The genes associated with these diseases encode transcription factors, structural components of the stroma and
Chitra Kannabiran, Sunita Chaurasia, Muralidhar Ramappa, Venkateswara Vinod Mootha   +3 more
doaj   +1 more source

Superficial Keratectomy: A Review of Literature

Frontiers in Medicine, 2022
Superficial keratectomy (SK) is the manual dissection of the superficial corneal layers (epithelium, Bowman's layer, and sometimes superficial stroma). SK is done using a surgical blade or diamond burr.
Farhad Salari, Alireza Beikmarzehei, George Liu, George Liu, Mehran Zarei-Ghanavati, Christopher Liu, Christopher Liu, Christopher Liu   +7 more
doaj   +1 more source

Update on the Corneal Dystrophies-Genetic Testing and Therapy [PDF]

, 2022
One major purpose of the IC3D Corneal Dystrophy Nomenclature Revision was to include genetic information with a goal of facilitating investigation into the pathogenesis, treatment, and perhaps even prevention of the corneal dystrophies, an ambitious goal.
Lisch, Walter, Jayne S. Weiss, Turunen, Joni A, Colin E. Willoughby, Walter Lisch, Willoughby, Colin E, Víctor Abad–Morales, Weiss, Jayne S, Abad-Morales, Víctor, Joni A. Turunen   +9 more
core   +1 more source

Detailed corneal and genetic characteristics of a pediatric patient with macular corneal dystrophy - case report

BMC Ophthalmology, 2021
Background Corneal dystrophies are a group of rare, inherited disorders that are usually bilateral, symmetric, slowly progressive, and not related to environmental or systemic factors. The majority of publications present the advanced form of the disease
Anna Nowińska, Edyta Chlasta-Twardzik, Michał Dembski, Ewa Wróblewska-Czajka, Klaudia Ulfik-Dembska, Edward Wylęgała   +5 more
doaj   +1 more source

Genetic epidemiology of epithelial-stromal TGFBI dystrophies in a large Korean population. [PDF]

Sci Rep
Epithelial-stromal TGFBI dystrophies are a group of inherited corneal disorders associated with variants in the TGFBI. This study investigated the allele frequency of major TGFBI variants and estimated the prevalence of epithelial-stromal TGFBI ...
Cho EH, Lee M, Ki CS, Seol CA, Jang MA.
europepmc   +2 more sources

Novel Mutations Associated With Various Types of Corneal Dystrophies in a Han Chinese Population. [PDF]

Front Genet, 2019
Aims: To study the genetic spectra of corneal dystrophies (CDs) in Han Chinese patients using next-generation sequencing (NGS).Methods: NGS-based targeted region sequencing was performed to evaluate 71 CD patients of Han Chinese ethnicity.
Zhang J, Wu D, Li Y, Fan Y, Chen H, Hong J, Xu J.   +6 more
europepmc   +2 more sources

Expression and Function of ZEB1 in the Cornea

Cells, 2021
ZEB1 is an important transcription factor for epithelial to mesenchymal transition (EMT) and in the regulation of cell differentiation and transformation.
Yingnan Zhang, Xiao Liu, Wei Liang, Douglas C. Dean, Lijun Zhang, Yongqing Liu   +5 more
doaj   +1 more source

Reduced quality of life in corneal dystrophy - a prospective case control study. [PDF]

BMC Ophthalmol
Background Corneal dystrophies are a group of rare eye diseases that can cause visual impairment and affect social well-being, independence, and active participation in society.
Elhardt C, Aamoon AZ, Hartmann LM, Grün CMS, Wolf A, Wertheimer CM.   +5 more
europepmc   +2 more sources