Results 41 to 50 of about 5,486 (209)

Current issues of differential diagnosis and treatment of congenital corneal opacities in children

open access: yesОфтальмохирургия, 2021
Purpose. To analyze the literature on the topic of congenital corneal opacities, their diagnosis, differential diagnosis, as well as the choice of optimal treatment tactics.Congenital corneal opacities (CCO), when effective treatment is delayed, usually ...
A. V. Pleskova   +2 more
doaj   +1 more source

Questions of treatment of degenerative changes in the anterior chamber of the eye

open access: yesМедицинский совет, 2016
Degenerative corneal diseases represent a relevant issue in the present-day ophthalmology. The key areas in the treatment of degenerative changes in the anterior chamber of the eye are anti-inflammatory, keratoprotective and tear substitute therapies ...
E. V. Yani, K. E. Seliverstova
doaj   +1 more source

Compound heterozygous mutations in TGFBI cause a severe phenotype of granular corneal dystrophy type 2

open access: yesScientific Reports, 2021
We investigated the clinical and genetic features of patients with severe phenotype of granular corneal dystrophy type 2 (GCD2) associated with compound heterozygosity in the transforming growth factor-β-induced (TGFBI) gene.
Ikhyun Jun   +5 more
doaj   +1 more source

Advances and challenges of CRISPR/Cas gene editing for corneal diseases. [PDF]

open access: yesAdv Ophthalmol Pract Res
Background: Corneal diseases are a major cause of global visual impairment, and current treatments remain inadequate for severe or refractory cases. The CRISPR/Cas system offers robust and precise gene-editing capabilities, yet its therapeutic potential ...
Han Y, Chen R, Shentu X.
europepmc   +2 more sources

Stem Cell Spheres for Corneal Regeneration

open access: yes, 2021
Corneal cells isolated from the peripheral cornea and limbus can be cultured in vitro under sphere-forming conditions which enrich for stem and progenitor cells. These stem cell-enriched spheres represent a mixed population of cells comprising epithelial,
Li, Ye   +7 more
core   +1 more source

Contact lenses for the treatment of ocular surface diseases

open access: yesIndian Journal of Ophthalmology, 2023
Contact lens wear is useful in ocular conditions such as high refractive errors, irregular astigmatism, corneal ectasias, corneal dystrophies, post-keratoplasty, post-refractive surgeries, trauma, and ocular surface diseases.
Namrata Sharma   +3 more
doaj   +1 more source

The roles of autophagy and mitophagy in corneal pathology: current knowledge and future perspectives

open access: yesFrontiers in Medicine, 2023
The cornea is the clear dome that covers the front portion of the globe. The primary functions of the cornea are to promote the refraction of light and to protect the eye from invading pathogens, both of which are essential for the preservation of vision.
Rajalakshmy Ayilam Ramachandran   +2 more
doaj   +1 more source

Corneal transplantation: Restoring sight to the blind

open access: yesActa Ophthalmologica, EarlyView.
Abstract Corneal blindness is one of the leading causes of vision loss worldwide. Transplantation of the cornea can restore vision and make blind patients see again. Corneal transplant surgery has undergone major evolution in recent decades with the advent of minimally invasive lamellar surgical approaches such as DMEK and DALK.
Claus Cursiefen
wiley   +1 more source

Recurrent Corneal Erosions in Corneal Dystrophies: a Review of the Pathogenesis, Differential Diagnosis, and Therapy

open access: yes, 2018
Introduction Recurrent corneal erosions in corneal dystrophies are visually significant and bothersome to patients. The goal of this article is to review the pathogenesis, differential diagnosis, and management of recurrent corneal erosions in corneal ...
Shahzad Mian, Amro Omari
core   +1 more source

Trends in indications and techniques of corneal transplantation in Iran from 2006 to 2013; an 8-year review

open access: yesJournal of Ophthalmic & Vision Research, 2016
Purpose: To report changing trends in indications and techniques of corneal transplantation in Iran. Methods: We reviewed eye bank records of 47,129 patients who had undergone corneal transplantation between 2006 and 2013 at different eye centers ...
Mozhgan Rezaei Kanavi   +6 more
doaj   +1 more source

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