Localization and expression of zonula occludins-1 in the rabbit corneal epithelium following exposure to benzalkonium chloride. [PDF]
PLoS ONE, 2012 Preservatives are a major component of the ophthalmic preparations in multi-dose bottles. The purpose of this study was to investigate the acute effect of benzalkonium chloride (BAC), a common preservative used in ophthalmic preparations, on the ...
Wensheng Chen +7 more
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Evaluation of artificial tears on cornea epithelium healing [PDF]
International Journal of Ophthalmology, 2018 AIM: To observe the efficacy of different artificial eye drops on corneal epithelium healing in rabbit. METHODS: Thirty-five rabbits with 6 mm diameter central corneal epithelium removed were randomly assigned to six groups: 0.9% normal saline (NS ...
Ying Zhang +4 more
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Kynurenic Acid Accelerates Healing of Corneal Epithelium In Vitro and In Vivo
Pharmaceuticals, 2021 Kynurenic acid (KYNA) is an endogenous compound with a multidirectional effect. It possesses antiapoptotic, anti-inflammatory, and antioxidative properties that may be beneficial in the treatment of corneal injuries.
Anna Matysik-Woźniak +7 more
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American Journal of Ophthalmology Case Reports, 2022 Purpose: Irregular corneal epithelium in limbal stem cell disease can cause visual acuity to deteriorate substantially when it reaches the pupil. In this case series, we assessed the effectiveness of simple corneal epithelial superficial keratectomy in ...
Aya Inamochi +4 more
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Core transcription regulatory circuitry orchestrates corneal epithelial homeostasis
Nature Communications, 2021 Corneal epithelium shares similar molecular signatures to other stratified epithelia. Here, the authors map super-enhancers and accessible chromatin in corneal epithelium, identifying a transcription regulatory circuit, including RUNX1, PAX6, and SMAD3 ...
Mingsen Li +18 more
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STAR Protocols, 2023 Summary: Existing flow cytometry approaches identify immune cells using the whole infected/inflamed cornea, which limits its ability to distinguish the immune cells infiltrating the corneal epithelium from the corneal stroma.
Mizumi Setia +2 more
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COMPARATIVE STUDY BETWEEN EPITHELIUM ON AND EPITHELIUM OFF COLLAGEN CROSS LINKING WITH RIBOFLAVIN AND UVR IN TREATMENT OF EARLY KERATOCONUS [PDF]
Egyptian Journal of Clinical Ophthalmology, 2020 Objective: To compare the safety and efficacy epithelium on versus epithelium off collagen crosslinking with riboflavin and UVR in treatment of early keratoconus. Patients and Methods: Thepresent study was a prospective, randomized study. 40 eyes from 25
Youssef, H. +2 more
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Comparison of corneal biological parameters between transepithelial and epithelium-off corneal cross-linking in keratoconus [PDF]
International Journal of Ophthalmology, 2021 AIM: To evaluate the differences in corneal biological parameters between transepithelial and epithelium-off corneal cross-linking in keratoconus.
Bo-Wen Ouyang +6 more
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Low‐intensity low‐frequency ultrasound mediates riboflavin delivery during corneal crosslinking
Bioengineering & Translational Medicine, 2023 We employed the mechanical effect from 40 kHz ultrasound (US) to improve the delivery of riboflavin into corneal stroma for collagen crosslinking, which can benefit the treatment of keratoconus and other corneal ectasias.
Zhe Sun +5 more
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Real-time polymerase chain reaction for the diagnosis of necrotizing herpes stromal keratitis [PDF]
International Journal of Ophthalmology, 2016 AIM: To design, optimize and validate a rapid, internally controlled real-time polymerase chain reaction (RT-PCR) test for herpes simplex virus (HSV) in the diagnosis of necrotizing herpes stromal keratitis. METHODS: Tears alone or together with corneal
Jun-Xin Ma, Lin-Nong Wang, Ru-Xia Zhou
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