Results 21 to 30 of about 44,117 (256)

Mechanobiology of the corneal epithelium

Experimental Eye Research, 2018
There has been a drive to develop new cell based therapies to treat corneal blindness, one of the most common causes of blindness worldwide. Mechanical and physical cues are known to regulate the behavior of many cell types, however studies examining these effects on corneal epithelial cells have been limited in number and their findings have not ...
Masterton, Sophia, Ahearne, Mark
openaire   +4 more sources

The core planar cell polarity gene, Vangl2, directs adult corneal epithelial cell alignment and migration [PDF]

Royal Society Open Science, 2016
This study shows that the core planar cell polarity (PCP) genes direct the aligned cell migration in the adult corneal epithelium, a stratified squamous epithelium on the outer surface of the vertebrate eye.
Amy S. Findlay, D. Alessio Panzica, Petr Walczysko, Amy B. Holt, Deborah J. Henderson, John D. West, Ann M. Rajnicek, J. Martin Collinson   +7 more
doaj   +1 more source

Deciphering the mechanoresponsive role of β-catenin in keratoconus epithelium

Scientific Reports, 2020
Keratoconus (KC) is a corneal dystrophy characterized by progressive ectasia that leads to severe visual impairment and remains one of the leading indications for corneal transplantation. The etiology is believed to be multifactorial and alterations have
Chatterjee Amit, Prema Padmanabhan, Janakiraman Narayanan   +2 more
doaj   +1 more source

Corneal epithelial thickness analysis of forme fruste keratoconus with optical coherence tomography [PDF]

International Journal of Ophthalmology, 2021
AIM: To explore the significance of corneal epithelial thickness analysis in diagnosing early keratoconus. METHODS: There were 26 clinical keratoconus, 21 forme fruste keratoconus, 40 high corneal astigmatism (ΔK) and 40 low ΔK eyes involved in the study.
Xiao-Long Yang, Yun Wang, Bao-Gen Luo, Yue Xu, Xiao-Feng Zhang   +4 more
doaj   +1 more source

A comparative study between epithelium-on and epithelium-off collagen cross-linking with riboflavin and ultraviolet radiation in the treatment of early keratoconus

Journal of the Egyptian Ophthalmological Society, 2016
Purpose We aimed to carry out a comparative study between epithelium-on and epithelium-off collagen cross-linking (CXL) in the treatment of early keratoconus. Patients and methods The present study was a prospective, randomized study. We included 40 eyes
Hassan S Yousef
doaj   +1 more source

Experience of Using Corneal Epithelium Protector Gel for the Treatment of Corneal Erosion for a Patient after Radial Keratotomy

Oftalʹmologiâ, 2022
Currently, one of the actual problems of pharmacotherapy is the treatment of recurrent corneal erosions. Traumatic and postoperative damage to the cornea can disrupt the connection between the basement membrane and the epithelium.
A. S. Semakina
doaj   +1 more source

Corneal collagen cross-linking and liposomal amphotericin B combination therapy for fungal keratitis in rabbits [PDF]

International Journal of Ophthalmology, 2016
AIM: To observe the therapeutic effect of corneal collagen cross-linking (CXL) in combination with liposomal amphotericin B in fungal corneal ulcers. METHODS: New Zealand rabbits were induced fungal corneal ulcers by scratching and randomly divided into
Zhao-Qin Hao, Jin-Xin Song, Shi-Yin Pan, Lin Zhang, Yan Cheng, Xian-Ning Liu, Jie Wu, Xiang-Hua Xiao, Wei Gao, Hai-Feng Zhu   +9 more
doaj   +1 more source

Evaluation of corneal epithelial mapping in type-2 diabetes mellitus

Journal of the Egyptian Ophthalmological Society
Aim To quantify corneal epithelial changes in type-2 diabetic patients (DM-2) using anterior-segment optical coherence tomography (AS-OCT). Setting BADR University Hospital, and Al-Mashreq Eye Center, Cairo, Egypt.
Esraa R. Hassaan, Mostafa M. Bahgat, Ahmed F. El-Shahed   +2 more
doaj   +1 more source

Partitioning and Spatial Distribution of Drugs in Ocular Surface Tissues

Pharmaceutics, 2021
Ocular drug absorption after eye drop instillation has been widely studied, but partitioning phenomena and spatial drug distribution are poorly understood.
Anusha Balla, Seppo Auriola, Angus C. Grey, Nicholas J. Demarais, Annika Valtari, Emma M. Heikkinen, Elisa Toropainen, Arto Urtti, Kati-Sisko Vellonen, Marika Ruponen   +9 more
doaj   +1 more source

Case Report of Restoration of the Corneal Epithelium in a Patient with Atopic Keratoconjunctivitis Resulting in Amelioration of Ocular Allergic Inflammation

Allergology International, 2010
: Background: Atopic and vernal keratoconjunctivitis are severe types of ocular allergic disease characterized not only by conjunctival inflammation but also by corneal involvement.
Ken Fukuda, Naoyuki Yamada, Teruo Nishida   +2 more
doaj   +1 more source