Results 71 to 80 of about 26,505 (263)

Deep anterior lamellar rekeratoplasty after anterior lamellar rekeratoplasty using femtosecond laser. A case report

Офтальмохирургия, 2013
We report a clinical case of femtosecond laser (FS) assisted deep anterior lamellar keratoplasty (DALK) performed with the IntraLase FS 60 kHz laser after a previous FS anterior lamellar keratoplasty (ALK). Patient, 28-year-old female with clear lamellar
N.P. Pashtayev, B.E. Malyugin, A.N. Pashtayev, K.I. Kustova, I.V. Drozdov, E.E. Ayba   +5 more
doaj  

Intrinsically Mitochondria‐Targeting Nanozyme via Coordination‐Assembly of Natural Quercetin for Cascade Antioxidant Therapy of Cerebral Ischemia‐Reperfusion Injury

Advanced Science, EarlyView.
This study uncovers that quercetin naturally targets mitochondria. By coordinating quercetin with Fe3+, we engineer an ultrasmall cascade nanozyme (MCN) with superoxide dismutase‐catalase activities. MCN crosses the damaged blood–brain barrier, scavenges mitochondrial ROS, prevents mitochondrial DNA leakage, and blocks the cGAS‐STING pathway, thereby ...
Wenxuan Zheng, Zhicheng Wang, Xin Zhou, Shuya Wang, Xiaojing Shi, Tingli Xiong, Ruishi Li, Yuting Lin, Zhen Chen, Jiawen Wei, Fei Li, Jinwen Ge, Kelong Ai, Chong Liu, Guiming Deng   +14 more
wiley   +1 more source

Application research of preservative-free 0.4% oxybuprocaine hydrochloride eye drops in pain management protocol in laser corneal refractive surgery

Yanke Xuebao
Objective: To evaluate the efficacy of preservative-free 0.4% oxybuprocaine hydrochloride eye drops in pain management during small incision lenticule extraction (SMILE) and femtosecond laser-assisted laser in situ keratomileusis (FS-LASIK), and to ...
WEI Nina, LIU Weimin, CHEN Xia, HUANG Shutian, CHEN Dongyan, ZHU Liangyong   +5 more
doaj   +1 more source

The two-year analysis of clinical and functional results of MyoRing implantation in patients with keratoconus

Офтальмохирургия, 2016
Purpose. A comparative analysis of clinical and functional parameters of the corneal surface in patients with keratoconus (KC) of the stages II, III after MyoRing implantation into the intrastromal pocket formed using the femtosecond laser according to ...
N. P. Pashtayev, N. A. Pozdeyeva, M. V. Sinitsyn   +2 more
doaj   +1 more source

Mechanical Activation of Piezo1 Drives Osteoarthritis Through Kdm5c‐Mediated Epigenetic Silencing

Advanced Science, EarlyView.
Excessive mechanical stress activates Piezo1, triggering Ca2+‐dependent cytoskeletal forces that deform the nucleus and reduce H3K4me3. Kdm5c demethylates H3K4me3 at Col2a1 and Runx3 promoters. Kdm5c knockout rescues degradation. Repurposed telmisartan directly inhibits Kdm5c, blocking this axis and showing disease‐modifying efficacy in mouse OA models
Tianyou Kan, Xuran Li, Han Wang, Lin Sun, Yao Wang, Jiangdong Wu, Junqi Cui, Yiqi Yang, Kai Yuan, Linyang Chu, Liao Wang, Hanjun Li, Mengning Yan, Zhifeng Yu   +13 more
wiley   +1 more source

Neuronal differentiation and tissue engineering strategies for central neurous system injury repair

BMEMat, EarlyView.
This review outlines tissue engineering advances for central nervous system (CNS) injury treatment, focusing on three core components: seed cells, inductive factors, and scaffold materials, with evaluation of their respective strengths and limitations. Tissue engineering for CNS injury repair.
Zhuqing Xia, Jinghui Zhang, Na Ren, Shuping Wang, Congcong Zhang, Nik Ahmad Nizam Nik Malek, Wan Hairul Anuar Kamaruddin, Chao Liu, Chunhui Sun, Jingang Wang   +9 more
wiley   +1 more source

Birefringent properties of the human cornea in vivo : towards a new model of corneal structure [PDF]

The fundamental corneal properties of mechanical rigidity, maintenance of curvature and optical transparency result from the specific organisation of collagen fibrils in the corneal stroma. The exact arrangement of stromal collagen is currently unknown
Misson, Gary P.
core  

All laser cataract surgery compared to femtosecond laser phacoemulsification surgery: corneal trauma

, 2017
The aim of this study was to evaluate corneal tissue trauma after femtosecond laser-assisted cataract surgery (FLACS) and phacoemulsification (femtophaco surgery) compared to FLACS and nanolaser emulsification (all laser surgery).
MATTEI, PETER ANGELO, TOTO, LISA, MASTROPASQUA, Leonardo, MASTROPASQUA, ALESSANDRA, Doronzo, E., VECCHIARINO, LUCA, Falconio, G   +6 more
core   +1 more source

Neurovascular coupling in bone regeneration: Mechanisms, advanced biomaterials and challenges

BMEMat, EarlyView.
This figure illustrates various material strategies for neurovascularized bone regeneration, including electroactive scaffolds, ion‐loaded materials, drug delivery systems, surface modifications, cells/cell products, growth factors, and peptides. These approaches aim to synergistically promote the regeneration of neural, vascular, and bone tissues ...
Yixin Ma, Nan Jiang, Liyuan Chen, He Zhang, Xinjia Cai, Karan Gulati, Danqing He, Zhigang Cai, Yan Liu   +8 more
wiley   +1 more source

A novel corneal indentation device for comparison of corneal tangent modulus before and after FS-LASIK in vivo

BioMedical Engineering OnLine
Background Corneal refractive laser surgery is widely used to correct myopia and astigmatism due to its safety and effectiveness. However, postoperative changes in corneal biomechanics, such as corneal ectasia, can occur, necessitating a deeper ...
Yan Zhang, Junyu Lin, Shu-Hao Lu, Jones Iok-Tong Chong, Cheng Yang, Jianqing Lan, Wenjuan Xie, Juan Li, David Chuen-Chun Lam, Dan Cao, Jin Zeng   +10 more
doaj   +1 more source