Potential benefits and risks of clinical xenotransplantation [PDF]
, 2012 The transplantation of organs and cells from pigs into humans could overcome the critical and continuing problem of the lack of availability of deceased human organs and cells for clinical transplantation.
Ayares, D, Cooper, DKC
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Medicina, 2023 Background: Chronic ocular graft-versus-host disease (oGVHD) is a common ocular complication following allogeneic hematopoietic stem cell transplantation (allo-HSCT), characterized by progressive inflammation of the ocular surface and refractory dry eye.
Yunjiao He +3 more
doaj +1 more source
Poly-l/dl-lactic acid films functionalized with collagen IV as carrier substrata for corneal epithelial stem cells [PDF]
, 2019 Limbal epithelial stem cells (LESCs) are responsible for the renewal of corneal epithelium. Cultivated limbal epithelial transplantation is the current treatment of choice for restoring the loss or dysfunction of LESCs.
Calonge Cano, Margarita +7 more
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Limbal stem cell transplantation: clinical results, limits, and perspectives [PDF]
, 2018 Limbal stem cell deficiency (LSCD) is a clinical condition characterized by damage of cornea limbal stem cells, which results in an impairment of corneal epithelium turnover and in an invasion of the cornea by the conjunctival epithelium.
Bruscolini, Alice +3 more
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A brief history of corneal transplantation: From ancient to modern
Oman Journal of Ophthalmology, 2013 This review highlights many of the fundamental concepts and events in the development of corneal transplantation - from ancient times to modern. Tales of eye, limb, and even heart transplantation appear in ancient and medieval texts; however, in the ...
Alexandra X Crawford +2 more
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Therapeutic Effect of Human Adipose Tissue-Derived Mesenchymal Stem Cells in Experimental Corneal Failure Due to Limbal Stem Cell Niche Damage [PDF]
, 2017 Producción CientíficaLimbal stem cells are responsible for the continuous renewal of the corneal epithelium. The destruction or dysfunction of these stem cells or their niche induces limbal stem cell deficiency (LSCD) leading to visual loss, chronic pain,
Calonge Cano, Margarita +7 more
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Stem Cell Research & Therapy, 2022 Background Corneal transplantation is the only way to treat serious corneal diseases caused by corneal endothelial dysfunction. However, the shortage of donor corneal tissues and human corneal endothelial cells (HCECs) remains a worldwide challenge.
Peng Sun +4 more
doaj +1 more source
Keratoprostheses for corneal blindness: a review of contemporary devices [PDF]
, 2015 According to the World Health Organization, globally 4.9 million are blind due to corneal pathology. Corneal transplantation is successful and curative of the blindness for a majority of these cases. However, it is less successful in a number of diseases
Avadhanam, Venkata +2 more
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Indications and surgical techniques for corneal transplantation at a tertiary referral center
Journal of Ophthalmic & Vision Research, 2019 Purpose: The study aimed to review the indications and techniques for corneal transplantation at a tertiary referral center over a 5-year period. Methods: Records of patients who underwent corneal transplantation at Khalili Medical Center, Shiraz, Iran ...
Hossein Jamali, Ahmad Reza Gholampour
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Quality of life and participation after corneal transplantation and potential predictors: A multicenter prospective cohort study. [PDF]
Acta OphthalmolAbstract Purpose To evaluate the long‐term effect of corneal transplantation on health‐ and vision‐related quality of life, visual functioning, and societal participation, and to assess potential predictors. Methods We conducted a multicenter prospective cohort study in 11 Dutch hospitals and eye clinics.
Elsman EBM +9 more
europepmc +2 more sources