Results 41 to 50 of about 74,669 (258)

Fast Event-based Corner Detection [PDF]

open access: yesProcedings of the British Machine Vision Conference 2017, 2017
Event cameras offer many advantages over standard frame-based cameras, such as low latency, high temporal resolution, and a high dynamic range. They respond to pixel-level brightness changes and, therefore, provide a sparse output. However, in textured scenes with rapid motion, millions of events are generated per second.
Müggler, Elias   +2 more
openaire   +3 more sources

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

A Fast and Reliable Corner Detector for Non-Uniform Illumination Mineshaft Images

open access: yesJournal of Intelligent Systems, 2013
We propose a fast and reliable corner detector that can detect corners under non-uniform illumination and fuzzy mineshaft images effectively. First, we presented an inner mask that used only four pixels to determine the flat and corner regions of an ...
Xing Yuanxiu   +3 more
doaj   +1 more source

Real UAV-Bird Image Classification Using CNN with a Synthetic Dataset

open access: yesApplied Sciences, 2021
A large amount of training image data is required for solving image classification problems using deep learning (DL) networks. In this study, we aimed to train DL networks with synthetic images generated by using a game engine and determine the effects ...
Ali Emre Öztürk, Ergun Erçelebi
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Geometric Parameters Calibration of Focused Light Field Camera Based on Edge Spread Information Fitting

open access: yesPhotonics, 2023
In this paper, a novel method based on edge spread information fitting (ESIF) is proposed to accurately calibrate the geometric parameters of a focused light field camera.
Wei Feng   +4 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

open access: yesMolecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi   +14 more
wiley   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

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