Results 51 to 60 of about 74,669 (258)

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

A Checkerboard Corner Detection Method for Infrared Thermal Camera Calibration Based on Physics-Informed Neural Network

Photonics
Control point detection is a critical initial step in camera calibration. For checkerboard corner points, detection is based on inferences about local gradients in the image.
Zhen Zuo, Zhuoyuan Wu, Junyu Wei, Peng Wu, Siyang Huang, Zhangjunjie Cheng   +5 more
doaj   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

A Motion Tracking System Based on The Polynomial Expansion and Harris Corner

Journal of Harbin University of Science and Technology, 2017
A motion tracking system based on polynomial expansion inter － frame estimation and Harris corner detection is proposed． The system transforms the video monitoring image into grayscale in order to feature extract， then determines the interested area to ...
YANG Guang-xue, HU Jia-wei, KANG Shou-qiang, LIANG Ya-qi, WANG Lei   +4 more
doaj   +1 more source

Analysis of the ship target detection in high-resolution SAR images based on information theory and Harris corner detection

EURASIP Journal on Wireless Communications and Networking, 2018
In order to make up the shortcomings of some existing ship target detection algorithms for high-resolution synthetic aperture radar (SAR) images, a ship target detection algorithm based on information theory and Harris corner detection for SAR images is ...
Yangyang Deng, Haijiang Wang, Shuo Liu, Min Sun, Xiaohong Li   +4 more
doaj   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Nearest Neighbour Corner Points Matching Detection Algorithm

MATEC Web of Conferences, 2015
Accurate detection towards the corners plays an important part in camera calibration. To deal with the instability and inaccuracies of present corner detection algorithm, the nearest neighbour corners match-ing detection algorithms was brought forward ...
Zhang Changlong, Wang Miaomiao, Li Yong, Yang Xuesong   +3 more
doaj   +1 more source

Harris corner detection on a NUMA manycore [PDF]

Future Generation Computer Systems, 2018
Corner detection is a key kernel for many image processing procedures including pattern recognition and motion detection. The latter, for instance, mainly relies on the corner points for which spatial analyses are performed, typically on (probably live) videos or temporal flows of images. Thus, highly efficient corner detection is essential to meet the
Haggui, Olfa, Tadonki, Claude, Lacassagne, Lionel, Sayadi, Fatma, Bouraoui, Ouni   +4 more
openaire   +2 more sources

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source