Results 121 to 130 of about 511,877 (268)

Animal models of hypertension and concurrent organs injury

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Although hypertension is a frequently seen chronic condition across the world, its exact cause remains unclear. Animal models are beneficial for clarifying the pathogenic mechanism of hypertension and examining new treatments. An optimal animal model for studies on hypertension must well mimic human‐like hemodynamics and pathophysiological structural ...
Ye Wang, Xiaoliang Jiang, Zhiwei Yang
wiley   +1 more source

Pericoronary adipose tissue computed tomography attenuation distinguishes different stages of coronary artery disease: a cross-sectional study [PDF]

open access: bronze, 2020
Andrew Lin   +7 more
openalex   +1 more source

Bilateral carotid‐jugular arteriovenous graft implantation in an ovine model is safe and durable for facilitation of arteriovenous graft innovation

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Eight sheep underwent bilateral carotid‐jugular AVG implantation. The AVGs were surveilled with duplex ultrasound at regular intervals for 6 months, at which point they were imaged fluoroscopically and explanted for gross and histologic evaluation. Primary patency of control grafts was 75% at 6 months and there were no major complications.
Matthew Schneck   +7 more
wiley   +1 more source

Continuous electrocardiogram monitoring in porcine model of myocardial ischemia reperfusion

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Wearable technology for continuous electrocardiogram monitoring can be utilized in porcine models of disease. Abstract As cardiovascular disease is the leading cause of global mortality, innovative animal models are vital to demonstrating the translational value of experimental discoveries. Investigations focused on myocardial remodeling after ischemia
Nathaniel Hyams   +8 more
wiley   +1 more source

Disruption of the Blood–Brain Barrier Predicts Progression of Cerebral Small Vessel Disease White Matter Hyperintensities

open access: yesAnnals of Neurology, EarlyView.
Objective The objective of this study was to test if blood–brain barrier (BBB) disruption, detected using dynamic susceptibility contrast (DSC) imaging, would predict progression of white matter hyperintensities (WMHs) over the subsequent year in patients with chronic cerebrovascular disease. Methods The study included patients with a history of stroke
Richard Leigh   +4 more
wiley   +1 more source

Everolimus‐Coated Laser‐Cut Self‐Expandable Metallic Stent Suppresses Stent‐Induced Tissue Hyperplasia in a Rat Gastric Outlet

open access: yesAdvanced NanoBiomed Research, EarlyView.
Everolimus‐coated laser‐cut self‐expandable metallic stents suppress stent‐induced tissue hyperplasia in the gastric outlet by reducing inflammation, fibrosis, and smooth muscle proliferation. Herein, we demonstrate the mechanical stability, sustained drug release, and histological benefits in a rat gastric outlet model, suggesting potential for ...
Yubeen Park   +10 more
wiley   +1 more source

MEW/PVA‐MA Hydrogel Vascular Grafts: Enhancing Hemocompatibility and Endothelialization

open access: yesAdvanced NanoBiomed Research, EarlyView.
A biomimetic vascular graft combining biofunctionalized PVA‐MA hydrogels with a MEW scaffold is developed for small‐diameter applications. Gel‐MA and Hep‐MA incorporation enhances endothelialization and hemocompatibility, respectively, targeting the acute biological responses.
Verena Kronberger   +8 more
wiley   +1 more source

The Prognostic Value of Diastolic and Systolic Mechanical Left Ventricular Dyssynchrony among Patients with Coronary Artery Disease and Heart Failure [PDF]

open access: bronze, 2017
Marat Fudim   +5 more
openalex   +1 more source

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