Results 231 to 240 of about 5,531,000 (262)

Association of obesity-metabolic phenotypes with coronary artery disease prevalence: interaction and exploratory mediation analyses of high-sensitivity C-reactive protein. [PDF]

Front Cardiovasc Med
Zhu C, Sun Y.
europepmc   +1 more source

The potential for biased signalling in the P2Y receptor family of GPCRs

British Journal of Pharmacology, EarlyView.
The purinergic receptor family is primarily activated by nucleotides, and contains members of both the G protein coupled‐receptor (GPCR) superfamily (P1 and P2Y) and ligand‐gated ion channels (P2X). The P2Y receptors are widely expressed in the human body, and given the ubiquitous nature of nucleotides, purinergic signalling is involved with a plethora
Claudia M. Sisk, Simon Pitchford, Graham Ladds   +2 more
wiley   +1 more source

Apolipoprotein E ε3/ε4 and coronary artery disease: lipid and non-lipid mechanisms in personalized prevention - narrative review. [PDF]

Front Cardiovasc Med
Diaconu R, Pădureanu V, Radu RI, Iovănescu M, Mirea O, Hădăreanu DR, Donoiu I.   +6 more
europepmc   +1 more source

Circulating Musclin is associated with skeletal muscle function and subclinical cardiac dysfunction in patients with cancer

British Journal of Pharmacology, EarlyView.
Background and Purpose Musclin (osteocrin) is a skeletal muscle‐derived peptide that has been implicated in cardioprotective signalling pathways. Its relevance in cancer patients, who frequently experience muscle wasting and cardiotoxicity, remains unclear. This study aimed to determine whether circulating Musclin levels reflect functional capacity and
Jannek Brauer, Daniel Finke, Sebastian Romann, Norbert Frey, Joerg Heineke, Lorenz H. Lehmann   +5 more
wiley   +1 more source

Cardiotoxicity of BRAF/MEK inhibitors

British Journal of Pharmacology, EarlyView.
Abstract Rapidly accelerated fibrosarcoma type B/B‐Raf proto‐oncogene, serine/threonine kinase (BRAF) and mitogen‐activated protein kinase (MEK) inhibitors have transformed outcomes in cancer therapy, particularly in melanoma. However, cardiovascular toxicities are increasingly recognized in real‐world clinical practice.
Katharina Seuthe, Valerie Lohner, Kevin Terre, Thomas Riffelmacher, Roman Pfister   +4 more
wiley   +1 more source

Colchicine to prevent cardiovascular events in thoracic surgery patients with or without coronary artery disease: a secondary analysis. [PDF]

Open Heart
Razeghi G, Wang MK, Devereaux PJ, Popova E, Chan MT, Sessler DI, Landoni G, Warwas M, McIntyre WF, Ofori S, Balasubramanian K, Tandon V, Finley CJ, Shanthanna H, Tallada AG, Cata JP, Choi EK, Shah SU, Srinathan SK, Reimer C, McLean SR, Trujillo JC, Fleischmann E, Kabon B, Voltolini L, Cruz P, Maziak DE, Gutiérrez-Soriano L, Sigamani A, Amir M, Conen D, COP-AF investigators.   +31 more
europepmc   +1 more source

CD93—An emerging vascular target in cancer therapy

British Journal of Pharmacology, EarlyView.
Abstract CD93 is a single‐pass transmembrane glycoprotein that belongs to the C‐type lectin domain group XIV family of proteins. Although it is known to be expressed in other cell types, namely, in some subsets of immune cells, CD93 is primarily expressed on endothelial cells, where it acts as a crucial regulator of angiogenesis.
Beatriz de Alves Pereira, Stefano Barbera, Roberta Lugano, Anna Dimberg   +3 more
wiley   +1 more source

Let's be CLEAR: Cath Lab Evaluation of Atherosclerotic Risk is a disease modifying opportunity. [PDF]

Br J Cardiol
Cunneen B, O'Callaghan D, O'Callaghan C, O'Neill F, Loo B, Wheen P, Moore D, Mulcahy D, Armstrong R, Maher V.   +9 more
europepmc   +1 more source

Sex differences in management and outcomes after out-of-hospital cardiac arrest with angiographically confirmed obstructive coronary artery disease. [PDF]

Resusc Plus
Svitekova K, Rob D, Mockova E, Kavalkova P, Pudil J, Dusik M, Macoun J, Svobodova E, Malik J, Valerianova A, Trhlikova S, Spicak J, Belohlavek J.   +12 more
europepmc   +1 more source

Electro-mechanical risk score for coronary artery disease risk estimation using seismocardiography. [PDF]

Eur Heart J Digit Health
Dehkordi P, Tavakolian K, Rocco T, Fozilov K, Yuldashov A, Zareba W, Yuldashov B, Atamuratov B, Marateb HR, Doniyorov S, Kurbanova B, Khosrow-Khavar F.   +11 more
europepmc   +1 more source