Effect of propranolol on regional myocardial function in anesthetized open-chest dogs with myocardial ischemia [PDF]
, 1978 Effects of propranolol on ischemic segmental function were studied in anesthetized open-chest dogs. Two segment-length gauges were used for measuring the regional myocardial function: one was sutured on to the left ventricular surface perfused by the ...
Haraoka, Shoichi +7 more
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The human coronary collateral circulation [PDF]
Heart, 2003 Eur J Clin Invest 2010; 40 (5): 465–476AbstractBackground Coronary collaterals are an alternative source of blood supply to myocardium jeopardized by ischaemia. Well‐developed coronary collateral arteries in patients with coronary artery disease (CAD) mitigate myocardial infarcts and improve survival.Methods and results Collateral arteries preventing
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Natriuretic peptides and integrated risk assessment for cardiovascular disease. an individual-participant-data meta-analysis [PDF]
, 2016 BACKGROUND: Guidelines for primary prevention of cardiovascular diseases focus on prediction of coronary heart disease and stroke. We assessed whether or not measurement of N-terminal-pro-B-type natriuretic peptide (NT-proBNP) concentration could enable ...
Adam S, Butterworth +53 more
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The Coronary Circulation as a Target of Cardioprotection [PDF]
Circulation Research, 2016 The atherosclerotic coronary vasculature is not only the culprit but also a victim of myocardial ischemia/reperfusion injury. Manifestations of such injury are increased vascular permeability and edema, endothelial dysfunction and impaired vasomotion, microembolization of atherothrombotic debris, stasis with intravascular cell aggregates, and finally ...
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Independent and joint effects of antibodies to human heat-shock protein 60 and Chlamydia pneumoniae infection in the development of coronary atherosclerosis [PDF]
, 2001 Background—Studies have suggested that the prevalence of antibodies against heat-shock proteins (HSPs), Chlamydia pneumoniae (Cpn), and cytomegalovirus (CMV) is associated with coronary artery disease (CAD), but the independent or joint effects of ...
Berencsi, Klára +11 more
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Effect of mediators on coronary circulation
European Heart Journal, 1991 A number of vasoactive mediators have been identified in plasma and in the heart. Some of them may be liberated in inflammatory heart disease. The action of mediators on coronary vasculature in various animal models and their potential role in inflammatory heart disease is reviewed. Their role in patients remains to be determined.
Ertl, G +4 more
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Glimepiride, a novel sulfonylurea, does not abolish myocardial protection afforded by either ischemic preconditioning or diazoxide [PDF]
, 2001 Background: The sulfonylurea glibenclamide (Glib) abolishes the cardioprotective effect of ischemic preconditioning (IP), presumably by inhibiting mitochondrial KATP channel opening in myocytes. Glimepiride (Glim) is a new sulfonylurea reported to affect
Baxter, G.F. +5 more
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THE ACTION OF THE NITRITES ON THE CORONARY CIRCULATION [PDF]
Archives of Internal Medicine, 1921 The nitrites have been employed in the treatment of angina pectoris since the time of Lauder Brunton, and it is well known that in many instances the pain subsides soon after the administration of a pearl of amyl nitrite or a pellet of nitroglycerin.
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Coronary artery spasm : role in acute myocardial ischaemia [PDF]
, 1992 Coronary artery spasm is an accepted cause of transient myocardial ischaemia in patients with variant angina. The electrocardiographic abnormality, ST segment elevation, which is a hallmark of this syndrome, resembles that seen experimentally when the ...
Xuereb, Mariosa, Xuereb, Robert G.
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Effects of balloon injury on neointimal hyperplasia in steptozotocin-induced diabetes and in hyperinsulinemic nondiabetic pancreatic islet-transplanted rats. [PDF]
, 2001 BACKGROUND: The mechanisms of increased neointimal hyperplasia after coronary interventions in diabetic patients are still unknown. METHODS AND RESULTS: Glucose and insulin effects on in vitro vascular smooth muscle cell (VSMC) proliferation and ...
Carriero M.V. +13 more
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