Results 61 to 70 of about 981,607 (247)

Esterified Cholesterol Conjugates Enable LNP‐Mediated mRNA Delivery to the Blood–Brain Barrier Following Intravenous Administration

open access: yesAdvanced Materials, EarlyView.
A cholesterol‐conjugated lipid library enabled the identification of a ligand‐free LNP platform for efficient mRNA delivery to brain endothelial cells via systemic administration. This platform achieves selective BBB targeting without disrupting barrier integrity, and enables modulation of neuroinflammation and vascular function without requiring trans‐
Zeru Tian   +7 more
wiley   +1 more source

HDL-C and systemic inflammatory response index mediate the association between visceral adipose tissue and risk of cardiovascular disease among young and middle-aged adults with prediabetes or diabetes: a national cohort study

open access: yesJournal of Translational Medicine
Background Visceral adipose tissue (VAT) is a harmful fat linked to cardiovasular disease (CVD). This study aims to investigate the relationship between VAT, as measured by dual-energy X-ray absorptiometry, and CVD risk in young and middle-aged adults ...
Wanzhou Wu   +3 more
doaj   +1 more source

WHAT IS NEW ABOUT INTERCORONARY ARTERIAL CONTINUITY?

open access: yesРоссийский кардиологический журнал, 2014
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Cem Bostan   +3 more
doaj   +1 more source

Magnetic Micro‐ and Nanorobots for Precision Thrombolysis: Design Strategies and Translational Challenges

open access: yesAdvanced Robotics Research, EarlyView.
Micro‐ and nanorobots for targeted thrombolysis. This perspective elaborates on the clinical indication of blood clot disorders and current limitations for treatment. As a novel, alternative solution, micro‐ and nanorobots can be used to treat and break down thrombi.
Joshua M. Mesfin   +3 more
wiley   +1 more source

Intelligent Micro/Nanorobots for Targeted Interventional Therapy: From Bench to Clinic

open access: yesAdvanced Robotics Research, EarlyView.
Zirui Zhang et al. reviewed the application and challenges of mobile nanomachines in interventional therapy. By converting exogenous energy, including chemical, magnetic, optical, and ultrasonic sources, into mechanical forces, micro/nanorobots (MNRs) enable precise actuation at unprecedented scales. Evolving far beyond traditional drug delivery, these
Zirui Zhang   +5 more
wiley   +1 more source

Association of change in cardiovascular health based on life's essential 8 with incident cardiovascular disease

open access: yesAmerican Journal of Preventive Cardiology
Objective: To evaluate whether and to what extent changes in cardiovascular health (CVH) based on life's essential 8 (LE8) are associated with incident cardiovascular disease (CVD). Methods: A total of 7,194 participants were derived from UK Biobank. CVH
Chao Song, Xunjie Cheng, Yongping Bai
doaj   +1 more source

Are percutaneous coronary interventions changing our coronary surgery practice? [PDF]

open access: yes, 2010
Aim: The aim of this retrospective study was to assess the impact of a growing percutaneous coronary intervention (PCI) program on our coronary artery bypass graft (CABG) practice.
Manche, Alexander, Casha, Aaron
core  

Pre‐Regenerative Endothelial Cells Empowered by Antler Blood Exosomes Orchestrate Peripheral Nerve Repair

open access: yesAdvanced Science, EarlyView.
The pre‐regenerative vascular niche (PVN) is essential for nerve repair, yet its endothelial blueprint remains unclear. We identified angiogenic ECs (AECs) as the dominant pre‐regenerative subset and found that antler blood–derived exosomes (AB‐EXO) promote repair via IMP3.
Jinsheng Huang   +11 more
wiley   +1 more source

Coronary Stenting in 15 Year-old Boy with Coronary Artery Stenosis Secondary to Kawasaki Disease [PDF]

open access: yes, 2000
Kawasaki disease is an acute febrile illness frequently developed in infants and children. This disease may involve coronary arteries in 15-25% of the patients and may progress to coronary aneurysms, ischemic cardiac diseases, and sudden cardiac death ...
고영국
core  

Impact of smoking reduction on coronary heart disease mortality trends during 1981-2000 in England and Wales. [PDF]

open access: yes, 2003
OBJECTIVE: To explore how much of the coronary heart disease (CHD) mortality fall in England and Wales can be attributed to changes in smoking prevalence.
S Capewell   +5 more
core   +1 more source

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