Results 81 to 90 of about 981,607 (247)

Intermittent Fasting Restores Cardiac Lipid Homeostasis in Diabetic Cardiomyopathy in Association With Akkermansia Muciniphila and 1‐methyl‐L‐histidine

Advanced Science, EarlyView.
Intermittent fasting reshapes the gut microbiota in diabetic cardiomyopathy, restoring Akkermansia muciniphila and the microbiota‐associated metabolite 1‐methyl‐L‐histidine. This shift is linked to improved cardiac lipid homeostasis, reduced lipid peroxidation, and attenuated myocardial injury, highlighting a gut microbiota–metabolite–lipid axis in ...
Kaiyuan Jiang, Fen Xiong, Yiwen Peng, Lingfei Meng, Xinran Wang, Yingruo Xu, Tian Tang, Hongchang Gao   +7 more
wiley   +1 more source

Biomarkers in acute coronary syndromes and their role in diabetic patients [PDF]

, 2005
Diabetic patients with acute coronary syndromes are at high risk for cardiovascular complications but risk stratification in these patients remains challenging.
Heeschen, Christopher, Christopher Heeschen   +1 more
core   +1 more source

Molecular Dynamics‐Guided Sterol Engineering of mRNA‐Lipid Nanoparticles Reprograms Biodistribution and Enhances Spleen‐Selective Immunity

Advanced Science, EarlyView.
Sterol engineering enables precise control of mRNA lipid nanoparticles by tuning membrane organization. Replacing cholesterol with bile acid‐derived sterols redirects protein expression from the liver to the spleen. Notably, CA‐20 LNP enhances antigen‐specific immune responses while exhibiting a favorable safety profile, highlighting sterols as a ...
Sanghyuk Jeon, Seo‐Hyeon Bae, Jungyong Ji, Jisun Lee, Hosam Choi, Min‐Ho Kang, Sang‐In Park, Hyemin Kim, Nakyung Lee, Hajin Lee, Seonghoon Kim, Jungmin Kim, Subin Yoon, Seonghyun Lee, Seongje Cho, Dahyeon Ha, Ayoung Oh, Sohee Jo, Huijeong Choi, Yeeun Lee, Sowon Lee, Hyo‐Jung Park, Gitak Nam, Jisu Shin, Yujin Kang, Wonpil Im, Kiyoun Lee, Jae‐Hwan Nam   +27 more
wiley   +1 more source

Association of Hematopoietic Loss of Y Chromosome With Atrial Fibrillation Incidence and Sex Disparity

JACC: Basic to Translational Science
Summary: Mosaic loss of chromosome Y (mLOY), the most common somatic mutation, prompts fibrotic heart diseases. We hypothesized that it accelerates atrial fibrillation (AF) and contributes to its sex disparity.
Tianqi Ma, MD, Chen Zhu, MB, Xunjie Cheng, PhD, Yuanfeng Huang, PhD, Jinchen Li, PhD, Yu Tan, MD, Yongping Bai, MD, PhD   +6 more
doaj   +1 more source

Low adiponectin levels are an independent predictor of mixed and non-calcified coronary atherosclerotic plaques. [PDF]

, 2009
Atherosclerosis is the primary cause of coronary artery disease (CAD). There is increasing recognition that lesion composition rather than size determines the acute complications of atherosclerotic disease.
Lebherz Corinna, Renee Stark, Christoph Becker, Stark, R.G., Stark, Renee, Tittus, Janine, Lehrke Michael, Lebherz, C., Greif, Martin, Greif Martin, Broedl Uli C., Reiser, M., Stark Renee, Reiser, Maximilian, Ziegler, Franz von, Alexander W Leber, Göke, B., Parhofer, K.G., Lebherz, Corinna, Alexander Becker, Leber, A.W., Leber, Alexander W., Michael Lehrke, Corinna Lebherz, Lehrke, Michael, Greif, M., von Ziegler Franz, Parhofer Klaus G., von Ziegler, A., Göke, Burkhard, Parhofer, Klaus G., Janine Tittus, Becker, C., Becker Alexander, Broedl, U.C., Reiser Maximilian, Broedl, Uli C., Martin Greif, Klaus G Parhofer, Tittus, J., Tittus Janine, Burkhard Göke, Göke Burkhard, Becker, F., Becker, Alexander, Maximilian Reiser, Uli C Broedl, Becker, Christoph, Becker Christoph, Leber Alexander W., Franz von Ziegler, Lehrke, M.   +51 more
core   +2 more sources

Photo‐Gated Corona Microfluidics

Advanced Science, EarlyView.
Photo‐gated corona microfluidics decouples optical programming from electric‐field actuation to enable reconfigurable manipulation on open, electrode‐pattern‐free surfaces. Near‐infrared irradiation locally melts paraffin, creating a reversible charge‐relaxation pathway that reconstructs the electric field.
Xiaxia Cui, Yiqing Liu, Xinyi Qiu, Manfei Liu, Biao Cheng, Yuan Zhou, Changguo Xue, Sheng Zhang, Xin Tang, Qiang Tang   +9 more
wiley   +1 more source

Psychological distress, physical illness, and risk of coronary heart disease [PDF]

, 2005
Study objective: The aims of this study are to confirm the association between psychological distress and coronary heart disease (CHD) using an epidemiological community study with hospital admissions data and to examine if any association is explained ...
Rasul, F., Stansfeld, S.A., Stansfeld, SA, Hart, CL, Davey Smith, G., Hart, C.L., Rasul, F, Davey Smith, G   +7 more
core   +1 more source

Sonoselective Transfection of Glioma Endothelium

Advanced Science, EarlyView.
Delivering non‐viral, gene‐bearing nanoparticles with thiol‐decorated surfaces to gliomas with focused ultrasound yields transfection tropism for endothelial cells. From this platform, “sonoselective” transfection of glioma endothelium is achieved via incorporation of an endothelial cell‐specific promoter.
Anna C. Debski, Catherine M. Gorick, Victoria R. Breza, Jackson Tirrell, Krishan Perumal, Katherine M. Nowak, Ji Song, Natasha D. Sheybani, Richard J. Price   +8 more
wiley   +1 more source

Hyperinsulinemia and Poor Coronary Collateral Circulation in Coronary Artery Occlusion: A Novel Finding, Yet of Therapeutic Significance or Not [Letter]

Diabetes, Metabolic Syndrome and Obesity, 2023
Mahnoor Asif,* Syeda Sakina Zehra,* Tanzila Siddiqui Karachi Medical and Dental College, Karachi, Pakistan*These authors contributed equally to this workCorrespondence: Syeda Sakina Zehra, Tel +92 3322609216, Email szehra362@gmail ...
Asif M, Zehra SS, Siddiqui T
doaj  

Optimism and recovery after acute coronary syndrome: a clinical cohort study. [PDF]

, 2015
Optimism is associated with reduced cardiovascular mortality, but its impact on recovery after acute coronary syndrome (ACS) is poorly understood. We hypothesized that greater optimism would lead to more effective physical and emotional adaptation after ...
Ronaldson, A, Molloy, GJ, Ronaldson, Amy; id_orcid, Wikman, A, Molloy, Gerard J, Wikman, Anna, Steptoe, A, Poole, L, Wikman, Anna,, Kaski, JC, Ronaldson, Amy, Steptoe, Andrew, Poole, Lydia, Kaski, Juan-Carlos   +13 more
core   +1 more source