Results 71 to 80 of about 13,767 (259)

WHAT IS NEW ABOUT INTERCORONARY ARTERIAL CONTINUITY?

Российский кардиологический журнал, 2014
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Cem Bostan, Ugur Coskun, Alev Arat Ozkan, Tevfik Gurmen   +3 more
doaj   +1 more source

Assessing the cost effectiveness of using prognostic biomarkers with decision models: case study in prioritising patients waiting for coronary artery surgery [PDF]

, 2009
: Objective To determine the effectiveness and cost effectiveness of using information from circulating biomarkers to inform the prioritisation process of patients with stable angina awaiting coronary artery bypass graft surgery.
Hemingway, Harry,, Hemingway, Harry, Sculpher, Mark,, Timmis, Adam,, Sculpher, Mark, Abrams, Keith,, Henriksson, M, K Fitzpatrick, Natalie,, Hingorani, Aroon D,, Chen, R, Kaski, Juan-Carlos,, Stenestrand, Ulf, Stenestrand, Ulf,, Hingorani, AD, Feder, G, Henriksson, Martin,, Janzon, M, Janzon, Magnus, Fitzpatrick, NK, Abrams, K, Damant, Jacqueline, Feder, Gene,, Palmer, S, Damant, Jacqueline,, Shipley, MJ, Chen, Ruoling, Timmis, A, K Fitzpatrick, Natalie, Abrams, Keith, Sculpher, M, Palmer, Stephen, Stenestrand, U, Keogh, B, Janzon, Magnus,, Damant, J, Feder, Gene, Shipley, Martin J, Henriksson, Martin, Kaski, JC, Hingorani, Aroon D, Keogh, Bruce, Keogh, Bruce,, Hemingway, H, Timmis, Adam, Fitzpatrick, Natalie K, Shipley, Martin J,, Kaski, Juan-Carlos   +46 more
core   +1 more source

Shellac‐Mediated Assembly of Nanoparticles for mRNA Delivery

Advanced Healthcare Materials, EarlyView.
A shellac‐mediated nanoparticle assembly strategy is presented, involving the complexation of mRNA and low‐molecular‐weight cationic molecules (e.g., polyethyleneimine, chitosan, lipids, and poly‐l‐lysine), followed by capping with shellac. This nanoparticle platform enables mRNA transfection following intravenous injection and facilitates gene editing
Meizhang Lu, Jingqu Chen, Zhixing Lin, Wanjun Xu, Tianzheng Wang, Shiyao Li, Die Yang, Frank Caruso   +7 more
wiley   +1 more source

Socioeconomic inequalities in coronary heart disease risk in older age: contribution of established and novel coronary risk factors

, 2009
Background: Evidence on socioeconomic inequalities in coronary heart disease (CHD) and their pathways in the elderly is limited. Little is also known about the contributions that novel coronary risk factors (particularly inflammatory/hemostatic markers ...
Morris, RW, R. W. MORRIS, Whincup, PH, Papacosta, O, Lennon, L., G. LOWE, O. PAPACOSTA, Lowe, G., Rumley, A., A. RUMLEY, S. G. WANNAMETHEE, Whincup, P. H., Ramsay, S. E., Wannamethee, SG, Morris, R. W., P. H. WHINCUP, Lowe, G.D., Papacosta, O., Wannamethee, S. G., S. E. RAMSAY, Ramsay, SE, Rumley, A, Lennon, L, L. LENNON, Lowe, G   +24 more
core   +1 more source

Functional Blood‐Brain Barrier Crossing by Biomimetic M13 Phage Vectors for Targeted Neuronal Delivery

Advanced Healthcare Materials, EarlyView.
This study investigates the M13 bacteriophage as a biomimetic nanovector capable of crossing in vitro models of the blood–brain barrier. By exploiting peculiar transcellular pathways, M13 avoids lysosomal degradation and preserves its structural integrity and functionality.
Silvia Vercellino, Lucia Pappagallo, Francesca De Chirico, Luca Boselli, Hazem Ahmed, Luca Spagnoletti, Giovanni Pittaluga, Paolo Emidio Costantini, Matteo Calvaresi, Pier Paolo Pompa, Alberto Danielli, Fabio Benfenati, Valentina Castagnola   +12 more
wiley   +1 more source

Dose-response associations of accelerometer-measured physical activity with mortality across frailty levels: A prospective cohort study

Experimental Gerontology
Background: Limited evidence, majorly based on questionnaire-derived measurements, was available to reflect long-term benefits of physical activity (PA) across different frailty levels.
Qunyong Peng, Tianqi Ma, Lingfang He, Xunjie Cheng, Wei Xie   +4 more
doaj   +1 more source

Association of coronary artery dominance and mortality rate and complications in patients with ST-segment elevation myocardial infarction treated with primary percutaneous coronary intervention

Journal of Research in Medical Sciences, 2020
Background: Percutaneous coronary intervention (PCI) is the treatment of choice for patients with ST-segment elevation myocardial infarction (STEMI). Effect of coronary artery dominance on the patients' outcome following primary PCI (PPCI) is not fully ...
Amir Mikaeilvand, Ata Firuozi, Hosseinali Basiri, Aida Varghaei, Peyman Izadpanah, Javad Kojuri, Alireza Abdi-Ardekani, Armin Attar   +7 more
doaj   +1 more source

Percutaneous coronary intervention in the elderly: changes in case-mix and periprocedural outcomes in 31758 patients treated between 2000 and 2007 [PDF]

, 2010
<p>Background: The elderly account for an increasing proportion of the population and have a high prevalence of coronary heart disease. Percutaneous coronary intervention (PCI) is the most common method of revascularization in the elderly.
Pell, A.C.H., Oldroyd, K.G., Flapan, A.D., Cathy Johnman, Pell, J.P., Mackay, D.F., Kevin P. Jennings, Jennings, K.P., Alastair C.H. Pell, Keith G. Oldroyd, Danny F. Mackay, Rachel Slack, John Irving, Slack, R., Eteiba, H., Irving, J., Jill P. Pell, Andrew D. Flapan, Johnman, C., Hany Eteiba   +19 more
core   +1 more source

Fructose‐Based Single‐Chain Polymer Nanoparticles for GLUT1–Mediated Delivery: Impact of Polymer Design on Uptake and In Vivo Performance

Advanced Healthcare Materials, EarlyView.
Single‐chain nanoparticles have been proposed as drug delivery carriers, but adding a tail can significantly enhance their performance. This was demonstrated using a tadpole‐like structure comprising a head prepared from a UV‐crosslinked fructose‐based glycopolymer capable of targeting GLUT receptors, combined with a PEG‐based tail. Compared with other
Hoang Yen Vo, Linqing Tian, Qiaoyun Wang, Evelyn Szabo, Rebecca Y. Lai, Fariba Dehghani, Martina H. Stenzel   +6 more
wiley   +1 more source

The Acute Responses of Different-sized Coronary Arteries to Testosterone

, 2012
Coronary arteries supply blood to the myocardium. The blood flow within the coronary arteries is altered by various compounds produced within the body. Sex hormones such as testosterone are known to cause the relaxation of large coronary arteries.
Madanu, Sampath
core