Results 51 to 60 of about 981,607 (247)

Pharmacology of the coronary circulation [PDF]

Canadian Journal of Anaesthesia, 1987
Until recently, the medical management of coronary artery disease consisted of depressing the heart's requirements for oxygen. Little thought was directed towards improving coronary blood flow as it was believed that atherosclerotic lesions were fixed, unchangeable obstructions.
openaire   +2 more sources

The Acute Responses of Different-sized Coronary Arteries to Testosterone [PDF]

, 2012
Coronary arteries supply blood to the myocardium. The blood flow within the coronary arteries is altered by various compounds produced within the body. Sex hormones such as testosterone are known to cause the relaxation of large coronary arteries.
Madanu, Sampath
core  

Microfluidic Nano‐Assembly of Red‐Blood‐Cell (RBC) Lipids and Components for Engineering Extracellular Vesicles

Advanced Healthcare Materials, EarlyView.
Engineered red blood cell‐derived extracellular vesicles (eRBCEVs) are synthesized via controlled microfluidic assembly from native RBC lipids, enabling tunable encapsulation of proteins, nucleic acids, nanoparticles, and viral vectors. The platform demonstrates reproducible nanoscale architecture, preserved membrane composition, and functional cargo ...
Chiranth K. Nagaraj, Xilal Y. Rima, Kim T. Nguyen, Courtney Culkins, Nana Boateng, Jacob Doon‐Ralls, Alejandro Bresolin, Xin Huang, Hong Li, Vahedi Amid, Ajeet Pal Singh, Dharti Shantaram, Anastasiia Amari, Mangesh D. Hade, Nicholas R. Merriam, Zachary D. Schultz, Scott Q. Harper, Nizar Y. Saad, Setty M. Magaña, Willa A. Hsueh, Rachel E. Kopec, Blaise R. Kimmel, Andre F. Palmer, Eduardo Reátegui   +23 more
wiley   +1 more source

Association between clinical presentations before myocardial infarction and coronary mortality: a prospective population-based study using linked electronic records. [PDF]

, 2014
BACKGROUND: Ischaemia in different arterial territories before acute myocardial infarction (AMI) may influence post-AMI outcomes. No studies have evaluated prospectively collected information on ischaemia and its effect on short- and long-term coronary ...
Hemingway, Harry, Herrett, Emily, Smeeth, Liam, Bhaskaran, Krishnan, Denaxas, Spiros, Timmis, Adam   +5 more
core   +1 more source

From Cell‐Derived Vesicles to Hybrid Nanovectors: Biological Membranes as Functional Blueprints for Gene Delivery

Advanced Healthcare Materials, EarlyView.
Biologically derived and hybrid nonviral nanovectors are examined as distinct but convergent design approaches. Integrating synthetic components with biologically functionalized membranes allows efficient interactions with complex cellular environments.
Clara Baldari, Claudia Leone, Gabriella Leccese, Claudia De Stradis, Alessandra Invidia, Concetta Quintarelli, Biagio De Angelis, Franco Locatelli, Giuseppe Gigli, Gabriele Maiorano, Ilaria Elena Palamà   +10 more
wiley   +1 more source

Optical Detection of Cellular Signals at Material Interfaces

Advanced Healthcare Materials, EarlyView.
Emerging functional materials are transforming optical detection of cellular signals. This review highlights optical techniques that exploit the unique optical properties of diverse materials to detect and quantify cellular electrical, chemical, and mechanical signals, and discusses key opportunities and challenges.
Xuchen Ren, Jitong Ren, Zixin Zhang, Koney Eungkon Kim, Francis L. Hong, Yuecheng Peter Zhou   +5 more
wiley   +1 more source

Association of hematopoietic loss of Y chromosome with valvular heart disease incidence and sex susceptibility

Journal of Advanced Research
Introduction: Hematopoietic mosaic Loss Of Y chromosome (LOY), a condition referring to the age-related loss of Y chromosome in a subset of blood cells, is associated with shortened life expectancy and increased risk of age-related diseases in men ...
Chenxuan Zhao, Yuanfeng Huang, Tianqi Ma, Xunjie Cheng, Jinchen Li, Guogang Zhang, Yongping Bai, Yu Tan   +7 more
doaj   +1 more source

Lignin Mimicking Protein Methylation Augments the Efficacy of FOLFOX Chemotherapy by Anchoring Thymidylate Synthase

Advanced Materials, EarlyView.
Lignin‐mimicking protein methylation can enhance the efficacy and mitigate the toxicity of the classic FOLFOX chemotherapy regimen. ABSTRACT FOLFOX has served as the standard chemotherapy regimen for advanced stages, specifically in the treatment of pancreatic, colorectal, and bladder cancers.
Shiyao Song, Yan‐Lai Tang, Xiaoting Liu, Jiayi Zheng, Chong Wu, Tang Li, Junhong Ye, Dianmin Xia, Yong Mei, Jingxuan Ma, Libin Huang, Xuequn Luo, Liheng Chen, Yanlin Qin, Weiling He   +14 more
wiley   +1 more source

Morphometric Reconstruction of Coronary Vasculature Incorporating Uniformity of Flow Dispersion

Frontiers in Physiology, 2018
Experimental limitations in measurements of coronary flow in the beating heart have led to the development of in silico models of reconstructed coronary trees.
Ravi Namani, Ravi Namani, Ghassan S. Kassab, Yoram Lanir   +3 more
doaj   +1 more source

Socioeconomic inequalities in coronary heart disease risk in older age: contribution of established and novel coronary risk factors [PDF]

, 2009
Background: Evidence on socioeconomic inequalities in coronary heart disease (CHD) and their pathways in the elderly is limited. Little is also known about the contributions that novel coronary risk factors (particularly inflammatory/hemostatic markers ...
Morris, RW, R. W. MORRIS, Whincup, PH, Papacosta, O, Lennon, L., G. LOWE, O. PAPACOSTA, Lowe, G., Rumley, A., A. RUMLEY, S. G. WANNAMETHEE, Whincup, P. H., Ramsay, S. E., Wannamethee, SG, Morris, R. W., P. H. WHINCUP, Lowe, G.D., Papacosta, O., Wannamethee, S. G., S. E. RAMSAY, Ramsay, SE, Rumley, A, Lennon, L, L. LENNON, Lowe, G   +24 more
core   +1 more source