Results 51 to 60 of about 1,815,731 (375)

A fresh look at coronary microembolization

Nature Reviews Cardiology, 2021
Mechanical stress from haemodynamic perturbations or interventional manipulation of epicardial coronary atherosclerotic plaques with inflammatory destabilization can release particulate debris, thrombotic material and soluble substances into the coronary
P. Kleinbongard, G. Heusch
semanticscholar   +1 more source

Independent and joint effects of antibodies to human heat-shock protein 60 and Chlamydia pneumoniae infection in the development of coronary atherosclerosis [PDF]

, 2001
Background—Studies have suggested that the prevalence of antibodies against heat-shock proteins (HSPs), Chlamydia pneumoniae (Cpn), and cytomegalovirus (CMV) is associated with coronary artery disease (CAD), but the independent or joint effects of ...
Berencsi, Klára, Boda, Krisztina, Burián, Katalin, Duba, Jenő, Endrész, Valéria, Füst, György, Gönczöl, Éva, Horváth, Laura, Kis, Zoltán, Prohászka, Zoltán, Romics, László, Virók, Dezső   +11 more
core   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

FEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan, Lu Qi, Pierre Zalloua   +2 more
wiley   +1 more source

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source

Reprogramming the myocardial infarction microenvironment with melanin-based composite nanomedicines in mice

Nature Communications
Myocardial infarction (MI) has a 5-year mortality rate of more than 50% due to the lack of effective treatments. Interactions between cardiomyocytes and the MI microenvironment (MIM) can determine the progression and fate of infarcted myocardial tissue ...
Yamei Liu, Shuya Wang, Jiaxiong Zhang, Quan Sun, Yi Xiao, Jing Chen, Meilian Yao, Guogang Zhang, Qun Huang, Tianjiao Zhao, Qiong Huang, Xiaojing Shi, Can Feng, Kelong Ai, Yongping Bai   +14 more
doaj   +1 more source

The Role of Collateral Circulation in Preserving Myocardial Function

Biomolecules & Biomedicine, 2006
The coronary collateral circulation is an alternative source of blood supply to the myocardium jeopardized by the failure of the original stenotic or occluded vessel to provide adequate blood flow to this region. One hundred coronary angiograms and left
Aida Hasanović, Amela Kulenović, Fuad Šišić   +2 more
doaj   +1 more source

Microbial risk factors of cardiovascular and cerebrovascular diseases: potential therapeutic options [PDF]

, 2008
Infection and inflammation may have a crucial role in the pathogenesis of atherosclerosis. This hypothesis is supported by an increasing number of reports on the interaction between chronic infection, inflammation, and atherogenesis.
Abbas, M.A., Comi, G, Corea, F, Fawi, G, Galantucci, S, Guenther, A, Kwan, Joseph W.   +6 more
core   +1 more source

Prevalence of Stroke and Diagnostic Performance of Emergency MRI in Acute Isolated Dizziness

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Stroke is frequently misdiagnosed in patients presenting with acute isolated dizziness; the optimal imaging modality for this population remains debated. This study aimed to determine the prevalence of stroke among patients with isolated dizziness and to assess the diagnostic accuracy of magnetic resonance imaging (MRI) and computed ...
Xiao Hu, Sijia Liu, Xiaosan Wu, Sunhong Yan, Jie Shen, Lei Zhu, Xueyun Liu, Zijie Wang, Chu Chen, Tiannan Yang, Chuanqin Fang, Qi Li   +11 more
wiley   +1 more source

Association between body fat variation rate and risk of diabetic nephropathy - a posthoc analysis based on ACCORD database

BMC Public Health
Background Weight control has consistently been regarded as a significant preventive measure against diabetic nephropathy. however, the potential impact of substantial fluctuations in body fat during this process on the risk of diabetic nephropathy ...
Shuai Li, Li Lin, Xiaoyue Chen, Siyu Liu, Ming Gao, Xunjie Cheng, Chuanchang Li   +6 more
doaj   +1 more source

Ultrasonic Atomization Spray Coating of PCL on an Mg‐Based Alloy Enhanced by Plasma Electrolytic Oxidation for Improved Adhesion, Corrosion Resistance, and Biocompatibility

Advanced Engineering Materials, EarlyView.
Plasma electrolytic oxidation is combined with ultrasonic spray deposition of polycaprolactone (PCL) on WE43 magnesium alloy to improve adhesion, corrosion resistance, and cytocompatibility. The hybrid coating demonstrates significantly reduced hydrogen evolution and enhances mechanical bonding, offering a promising strategy for next‐generation ...
Seyed Masih Mousavizadeh, Atiyeh Adelinia, Frederick D. Crowley, Jamal Seyyed Monfared Zanjani, John J. E. Mulvihill, Mingzhi Yu, Ehsan Rezvani, Matthijn de Rooij, Michael D. Gilchrist, Nan Zhang   +9 more
wiley   +1 more source