HAeMODYNAMIC CONSEQUENCES OF CORONARY HEART DISEASE WITH OBSERVATIONS DURING ANGINAL PAIN AND ON THE EFFECT OF NITROGLYCERINE [PDF]
Ottar Müller, K‐A Rørvik
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Genetic variants associated with Lp(a) lipoprotein level and coronary disease.
BACKGROUND An increased level of Lp(a) lipoprotein has been identified as a risk factor for coronary artery disease that is highly heritable. The genetic determinants of the Lp(a) lipoprotein level and their relevance for the risk of coronary disease are
R. Clarke+22 more
semanticscholar +1 more source
Berberine is a Novel Mitochondrial Calcium Uniporter Inhibitor that Disrupts MCU‐EMRE Assembly
Berberine, a safe and FDA‐approved drug, is identified as a novel mitochondrial calcium uniporter (MCU) inhibitor. By disrupting MCU‐EMRE interaction, Berberine prevents mitochondrial calcium overload and protects against ischemia/reperfusion injury, offering a promising therapeutic strategy for diseases linked to mitochondrial calcium dysregulation ...
Haixin Zhao+17 more
wiley +1 more source
Performance Analysis of Multiclass Support Vector Machine Classification for Diagnosis of Coronary Heart Diseases [PDF]
Automatic diagnosis of coronary heart disease helps the doctor to support in decision making a diagnosis. Coronary heart disease have some types or levels. Referring to the UCI Repository dataset, it divided into 4 types or levels that are labeled numbers 1-4 (low, medium, high and serious).
arxiv
Macrophage HM13/SPP Enhances Foamy Macrophage Formation and Atherogenesis
Previous research suggests that AIP may prevent atherogenic foamy macrophage formation. This study reveals that AIP, via its chaperone interaction with AHR, inhibits p38‐c‐JUN‐mediated transactivation of HM13, which encodes the ERAD protease HM13/SPP. HM13/SPP promotes foamy macrophage formation in addition to atherogenesis and plaque foamy macrophage ...
Yu Cao+15 more
wiley +1 more source
Extracellular Matrix Targeted MRI Probes
Gadolinium based MRI probes targeted to ECM components, either proteins or enzymes, hold promise for accurate molecular characterization and staging of fibrotic diseases in vivo. Non‐covalent binding probes (1), reactive probes (2), and enzyme‐responsive probes (3) are discussed.
Giuseppe Digilio+3 more
wiley +1 more source
The Circulating Lipids and Lipoproteins in Coronary Artery Disease [PDF]
M.F. Oliver, G.S. Boyd
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This study reveals a novel crosstalk between hepatic SREBP2‐mediated cholesterol biosynthesis pathway and peripheral lipoprotein lipase‐mediated lipolysis pathway in the regulation of systemic lipid metabolism. Notably, the lipid‐lowering effects of SREBP2 inhibition are independent of a functional LDL receptor, highlighting the potential of acute ...
Yifan Wang+13 more
wiley +1 more source
Utilizing AI Language Models to Identify Prognostic Factors for Coronary Artery Disease: A Study in Mashhad Residents [PDF]
Abstract: Background: Understanding cardiovascular artery disease risk factors, the leading global cause of mortality, is crucial for influencing its etiology, prevalence, and treatment. This study aims to evaluate prognostic markers for coronary artery disease in Mashhad using Naive Bayes, REP Tree, J48, CART, and CHAID algorithms.
arxiv
PREOPERATIVE PREPARATION OF THE PATIENT WITH CORONARY ARTERY DISEASE [PDF]
Samuel Bellet
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