Results 201 to 210 of about 1,382,114 (327)

PAR1 (Protease-Activated Receptor 1) Pepducin Therapy Targeting Myocardial Necrosis in Coronary Artery Disease and Acute Coronary Syndrome Patients Undergoing Cardiac Catheterization [PDF]

, 2020
Athan Kuliopulos, Paul A. Gurbel, Jeffrey J. Rade, Carey Kimmelstiel, Susan E. Turner, Kevin P. Bliden, Elizabeth K. Fletcher, Daniel H. Cox, Lidija Covic, on behalf of the TRIP-PCI Investigators   +9 more
openalex   +1 more source

Boron Nitride Nanomaterials Trigger Immunomodulatory Effects in Human Broncho‐Epithelial Cells by Modulating Eicosanoid Lipid Signaling

Advanced Science, EarlyView.
This study demonstrates that BNNT exposure disrupts lipid homeostasis in bronchial epithelial cell cultures and activates eicosanoid lipid biosynthesis, producing inflammatory lipid mediators like leukotrienes. These effects are more pronounced in asthmatic cell cultures compared to healthy ones.
Govind Gupta, Jonas Bossart, Sènan Mickael D'Almeida, Luis Augusto Visani de Luna, Christoph Schwärzler, Tingting Fu, Vanesa Ayala‐Nunez, Alexander Gogos, Marija Buljan, Vera M Kissling, Emmanuel Flahaut, Miguel Garcia, Cyrill Bussy, Peter Wick, Tina Buerki‐Thurnherr   +14 more
wiley   +1 more source

Inactivating Variants in ANGPTL4 and Risk of Coronary Artery Disease [PDF]

, 2016
Frederick E. Dewey, Viktoria Gusarova, Colm O’Dushlaine, Omri Gottesman, Jesus Trejos, Charleen Hunt, Cristopher V. Van Hout, Lukas Habegger, David G. Buckler, Ka-Man V. Lai, Joseph B. Leader, Michael F. Murray, Marylyn D. Ritchie, H. Lester Kirchner, David H. Ledbetter, John S. Penn, Alexander Lopez, Ingrid B. Borecki, John D. Overton, Jeffrey G. Reid, David J. Carey, Andrew Murphy, George D. Yancopoulos, Aris Baras, Jesper Gromada, Alan R. Shuldiner   +25 more
openalex   +1 more source

Neuroprotective Effects of Time‐Restricted Feeding Combined With Different Protein Sources in MPTP‐Induced Parkinson's Disease Mice Model and Its Modulatory Impact on Gut Microbiota Metabolism

Advanced Science, EarlyView.
Time‐restricted feeding (TRF) exerts protein‐dependent neuroprotective effects in an MPTP‐induced Parkinson's disease model. In casein‐fed mice, TRF improves gut barrier integrity and reduces neuroinflammation, possibly via modulation of Allobaculum and BCAAs.
Ting Li, Jian Wu, Sheng‐Yang Zhou, Ming‐An Li, Li‐Ping Zhao, Ao Wang, Yi‐Zhi Song, Wen‐Yan Huang, Lu‐Lu Tan, Chen‐Meng Qiao, Wei‐Jiang Zhao, Chun Cui, Yan‐Qin Shen   +12 more
wiley   +1 more source

Six-Year Outcomes of CABG vs PCI in Diabetic Patients with Multivessel Coronary Disease. [PDF]

Med Sci Monit
Jonik S, Piasecki A, Jastrzębska A, Opolski G, Grabowski M, Huczek Z, Kochman J.   +6 more
europepmc   +1 more source

Crossing the Blood–Brain Barrier with Molecularly Imprinted Polymeric Nanocarriers: An Emerging Frontier in Brain Disease Therapy

Advanced Science, EarlyView.
Molecularly imprinted polymeric nanocarriers (nanoMIPs) offer robust, antibody‐mimetic platforms to overcome the blood‐brain barrier. The article surveys nanoMIP design and ligand‐directed surface engineering that harness receptor‐mediated transcytosis, and highlights therapeutic and diagnostic applications in neurodegeneration, brain tumors and ...
Ranjit De, Shuliang Shi, Kyong‐Tai Kim
wiley   +1 more source

Prognostic value of SYNTAX score, intravascular ultrasound and near-infrared spectroscopy in coronary disease: 12-year follow-up of ATHEROREMO. [PDF]

Clin Res Cardiol
Meuleman VG, Vanmaele A, Da Veiga Fernandes de Mira JM, Akkerhuis KM, Oemrawsingh RM, Vroegindewey MM, Cheng JM, Garcia-Garcia HM, Daemen J, van Mieghem NM, Serruys PW, van Geuns RJ, Boersma E, Kardys I.   +13 more
europepmc   +1 more source

Impact of clinical signs and genetic diagnosis of familial hypercholesterolaemia on the prevalence of coronary artery disease in patients with severe hypercholesterolaemia [PDF]

, 2017
Hayato Tada, Masa‐aki Kawashiri, Atsushi Nohara, Akihiro Inazu, Hiroshi Mabuchi, Masakazu Yamagishi   +5 more
openalex   +1 more source

Multi‐View Biomedical Foundation Models for Molecule‐Target and Property Prediction

Advanced Science, EarlyView.
Molecular foundation models can provide accurate predictions for a large set of downstream tasks. We develop MMELON, an approach that integrates pre‐trained graph, image, and text foundation models and validate our multi‐view model on over 120 tasks, including GPCR binding.
Parthasarathy Suryanarayanan, Yunguang Qiu, Shreyans Sethi, Diwakar Mahajan, Hongyang Li, Yuxin Yang, Elif Eyigoz, Aldo Guzmán‐Sáenz, Daniel E. Platt, Timothy H. Rumbell, Kenney Ng, Sanjoy Dey, Myson Burch, Bum Chul Kwon, Pablo Meyer, Feixiong Cheng, Jianying Hu, Joseph A. Morrone   +17 more
wiley   +1 more source

Evaluation of the relative benefits of FFR-guided, angiography-guided CR or culprit-only revascularization in patients with multivessel coronary disease: a systematic review and meta-analysis. [PDF]

BMC Cardiovasc Disord
Liu XY, Wu XD, Lin Y, Lin X, Li YY, Ye BH, Sun JC.   +6 more
europepmc   +1 more source