Results 11 to 20 of about 972,701 (299)

Antioxidants and Coronary Heart Disease

Annals of Medicine, 1994
This review briefly summarizes the scientific evidence for a possible role of antioxidants in the prevention of coronary heart disease (CHD). Antioxidants in our diet include vitamins E, C, and beta-carotene, whereas selenium is an integral part of the antioxidant enzyme glutathione peroxidase (GSHPx).
Poppel, G. van, Kardinaal, A., Princen, H., Kok, F.J.   +3 more
openaire   +5 more sources

Causal relevance of blood lipid fractions in the development of carotid atherosclerosis: Mendelian randomization analysis. [PDF]

, 2013
BACKGROUND: Carotid intima-media thickness (CIMT), a subclinical measure of atherosclerosis, is associated with risk of coronary heart disease events. Statins reduce progression of CIMT and coronary heart disease risk in proportion to the reduction in ...
Baldassarre, Damiano, Casas, Juan-Pablo, de Faire, Ulf, Deanfield, John, Drenos, Fotios, Gertow, Karl, Gigante, Bruna, Hamsten, Anders, Hingorani, Aroon D, Holmes, Michael V, Humphries, Steve E, Kivimaki, Mika, Kumari, Meena, Langenberg, Claudia, Sennblad, Bengt, Shah, Sonia, Strawbridge, Rona J, Swerdlow, Daniel I, Talmud, Philippa J, Tremoli, Elena, Veglia, Fabrizio, Wareham, Nick, Whittaker, John   +22 more
core   +1 more source

Alcohol and Coronary Heart Disease [PDF]

International Journal of Epidemiology, 1984
The data on two questions are reviewed: does heavy alcohol intake increase the risk of coronary heart disease (CHD)? And, is moderate intake protective? Identified alcoholics and problem drinkers have an increased risk of CHD, and in Britain there is a correlation among 22 towns, between the proportion of heavy drinkers in a town and CHD mortality.
openaire   +4 more sources

Depression and Coronary Heart Disease [PDF]

ISRN Cardiology, 2012
There are exciting findings in the field of depression and coronary heart disease. Whether diagnosed or simply self-reported, depression continues to mark very high risk for a recurrent acute coronary syndrome or for death in patients with coronary heart disease.
openaire   +3 more sources

Genetic Loci associated with C-reactive protein levels and risk of coronary heart disease. [PDF]

, 2009
Plasma levels of C-reactive protein (CRP) are independently associated with risk of coronary heart disease, but whether CRP is causally associated with coronary heart disease or merely a marker of underlying atherosclerosis is uncertain.
Anand, S.S., Ashby, D., Bennett, D., Braund, P., Brown, I.J., Chambers, J.C., Clarke, R., Coin, L., Collins, R., Elliott, P., Engert, J.C., Erdmann, J., Farrall, M., Freimer, N.B., Froguel, P., Hall, A.S., Hamsten, A., Hopewell, J.C., Jarvelin, M.R., Kooner, J.S., Lim, N., McCarthy, M.I., Mooser, V., Mt-Isa, S., Peden, J.F., Peltonen, L., Ruokonen, A., Samani, N.J., Schunkert, H., Scott, J., Tzoulaki, I., Vollenweider, P., Waeber, G., Waterworth, D.M., Watkins, H., Zhang, W.   +35 more
core   +1 more source

Do patients with suspected heart failure and preserved left ventricular systolic function suffer from "diastolic heart failure" or from misdiagnosis? A prospective descriptive study [PDF]

, 2000
OBJECTIVES: To characterise the clinical features of patients with suspected heart failure but preserved left ventricular systolic function to determine if they have other potential causes for their symptoms rather than being diagnosed with 'diastolic ...
Caruana, L., Davie, A.P., McMurray, J., Petrie, M.C.   +3 more
core   +2 more sources

Diabetes mellitus and ischemic heart disease. the role of ion channels [PDF]

, 2018
Diabetes mellitus is one the strongest risk factors for cardiovascular disease and, in particular, for ischemic heart disease (IHD). The pathophysiology of myocardial ischemia in diabetic patients is complex and not fully understood: some diabetic ...
De Marchis, Marialaura, D’Amato, Andrea, Fedele, Francesco, Mancone, Massimo, Netti, Lucrezia, Palmirotta, Raffaele, Pucci, Mariateresa, Severino, Paolo, Volterrani, Maurizio   +8 more
core   +2 more sources

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

FEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan, Lu Qi, Pierre Zalloua   +2 more
wiley   +1 more source

Coronary Heart Disease [PDF]

, 2020
Social determinants of health are factors that are primarily responsible for health inequities. This chapter discusses social determinants of health from the perspectives of socioeconomic status (SES) and coronary heart disease (CHD). We are particularly concerned with the pathways through which socioeconomic inequalities are translated into CHD and ...
Katsunori Kondo, Hiroko Yamamoto, Hirohito Tsuboi, Hiroshi Kaneko   +3 more
openaire   +2 more sources

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source