Effect of Vascepa (icosapent ethyl) on progression of coronary atherosclerosis in patients with elevated triglycerides (200-499 mg/dL) on statin therapy: Rationale and design of the EVAPORATE study. [PDF]
Despite reducing progression and promoting regression of coronary atherosclerosis, statin therapy does not fully address residual cardiovascular (CV) risk.
Brent Muhlestein, J +5 more
core +2 more sources
AIMS To investigate the association between pericoronary adipose tissue (PCAT) computed tomography (CT) attenuation derived from coronary computed tomography angiography (CTA) and coronary flow reserve (CFR) by positron emission tomography (PET) in ...
C. Nomura +10 more
semanticscholar +1 more source
Adaptive 4D‐Printed Vascular Stents With Low‐Temperature‐Activated and Intelligent Deployment
Microarchitected coronary artery stents were fabricated using a polycaprolactone (PCL)‐based shape memory polymer (SMP) composite via projection micro‐stereolithography (PµSL) 4D printing. By incorporating diethyl phthalate (DEP) as a plasticizer, the thermal transition temperature (Ttran) was modulated to about 37°C, enabling rapid and autonomous ...
Yannan Li +12 more
wiley +1 more source
Myocardial infarction with non-obstructive coronary arteries (MINOCA) accounts for 5% to 15% of myocardial infarction (MI) cases; it presents with clinical signs of MI without significant coronary artery obstruction.
Stoenescu Andra Ioana +2 more
doaj +1 more source
Heparinase selectively sheds heparan sulphate from the endothelial glycocalyx [PDF]
A healthy vascular endothelium is coated by the endothelial glycocalyx. Its main constituents are transmembrane syndecans and bound heparan sulphates. This structure maintains the physiological endothelial permeability barrier and prevents leukocyte and ...
Becker, Bernhard F. +6 more
core +1 more source
Polyferrocene block copolymers are synthesized and assembled into micron‐sized polymer cubosomes with double diamond lattice and pore diameter of ≈30 nm. The ferrocene functionality is retained within the polymer cubosome wall as demonstrated on supramolecular modification, and oxidative disassembly.
Chin Ken Wong +4 more
wiley +1 more source
Sarcopenic obesity and risk of cardiovascular disease and mortality: a population-based cohort study of older men. [PDF]
OBJECTIVES: To examine associations between sarcopenia, obesity, and sarcopenic obesity and risk of cardiovascular disease (CVD) and all-cause mortality in older men. DESIGN: Prospective cohort study.
Atkins, JL +5 more
core +1 more source
Cold Quad‐Modal Nanocomplex for Precise and Quantitative In Vivo Stem Cell Tracking
Multimodal albumin–bismuth sulfide–superparamagnetic iron oxide (ABS) nanocomplexes are developed for stem cell tracking across four different imaging modalities: MRI, MPI, MSOT, and CT. Combining its flexibility with high sensitivity, this quad‐modal imaging agent enables a robust quantification of ABS‐labeled stem cells in vivo.
Ali Shakeri‐Zadeh +4 more
wiley +1 more source
The XIIIth Banff Conference on Allograft Pathology: The Banff 2015 Heart Meeting Report: Improving Antibody-Mediated Rejection Diagnostics: Strengths, Unmet Needs, and Future Directions. [PDF]
The 13th Banff Conference on Allograft Pathology was held in Vancouver, British Columbia, Canada from October 5 to 10, 2015. The cardiac session was devoted to current diagnostic issues in heart transplantation with a focus on antibody-mediated rejection
Angelini, A +18 more
core +1 more source
PREdicting LNP In Vivo Efficacy (PRELIVE) framework enables the prediction of lipid nanoparticle (LNPs) organ‐specific delivery through dual modeling approaches. Composition‐based models using formulation parameters and protein corona‐based models using biological fingerprints both achieve high predictive accuracy across multiple organs.
Belal I. Hanafy +3 more
wiley +1 more source

