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Inflammation markers and coronary heart disease
Current Opinion in Lipidology, 1999Evidence supports the position that the chronic atherothrombotic process is intimately associated with what has classically been called 'inflammation'. Proteins that are part of the acute phase response (e.g. fibrinogen, C-reactive protein) are sensitive markers of low-level inflammation, and in population studies, inflammation marker levels at the ...
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Targeting Inflammation in Coronary Artery Disease
New England Journal of Medicine, 2017For more than 20 years, our understanding of the biology of atherosclerosis has incorporated the so-called inflammatory hypothesis.1,2 Inflammatory cells and signals drive the healing response to vascular injury, allowing the initiation and growth of atherosclerotic plaque. Inflammatory reactions probably increase plaque instability, possibly resulting
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Inflammation and Coronary Artery Disease
New England Journal of Medicine, 1994Recent research suggests that focal inflammation in the coronary arteries may be involved in the genesis of unstable coronary syndromes. In this issue of the Journal, Liuzzo et al.1 report that the acute-phase reactants, C-reactive protein and serum amyloid A protein, were elevated in most of their patients with a diagnosis of unstable angina (based on
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Inflammation in Acute Coronary Syndromes
1997Coronary atherosclerosis without acute thrombosis is generally a benign disease that is asymptomatic or presents as chronic stable angina. The great majority of patients can be treated pharmacologically. For those with intractable angina, percutaneous and surgical revascularization are available with high initial success and good long-term prognosis ...
P. R. Moreno, J. T. Fallon
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Inflammation in coronary atherosclerosis: diagnosis and treatment
HeartCoronary atherosclerosis is a chronic condition characterised by the development of an atherosclerotic plaque in the inner layer of the coronary artery, mainly associated with cholesterol accumulation and favoured by endothelial dysfunction related to other cardiovascular risk factors, such as smoking, diabetes and hypertension.
Giovanni Occhipinti +9 more
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Inflammation and Infection in Acute Coronary Syndromes
The Journal of Cardiovascular Nursing, 2000Basic science research has revealed that monocytes and macrophages are important factors in atherogenesis. Immune system activation occurs at all stages of plaque formation, from the fatty streak to an advanced, complicated lesion. The inflammatory response not only stimulates changes in coronary artery endothelial cells causing endothelial injury and ...
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Inflammation and Coronary Heart Disease: An Overview
Cardiology in Review, 2001About half of the patients presenting with myocardial infarction do not have the classic risk factors. This finding has stimulated a search for other factors that may be responsible and, when present, may help to predict which patients are at greatest risk for myocardial infarction and other cardiovascular events.
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Inflammation in atherosclerosis and acute coronary syndromes
International Congress Series, 2002Abstract Research during the last decade has provided evidence of an important role of inflammation in the evolution of atherosclerosis and cardiovascular disease. This review discusses the evidence of local and systemic inflammatory responses in atherosclerosis and acute coronary syndromes.
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Coronary inflammation on chest computed tomography and COVID-19 mortality
European RadiologyD. Tuttolomondo +10 more
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[Inflammation and acute coronary syndromes].
Revista espanola de cardiologia, 2001A great variety of stimuli, such as free radicals, oxidized LDL or some bacteria or virus infections, can act upon the vascular surface and lead to the development of an acute inflammatory reaction. There is more and more evidence supporting the hypothesis that the mechanism responsible for the transformation of a non-complicated atherosclerotic lesion
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