Results 11 to 20 of about 455,893 (183)

Effect of sodium-glucose Co-transporter 2 inhibitors on coronary microcirculation [PDF]

Frontiers in Pharmacology
Coronary microvascular disease (CMVD) has emerged as a new target for the occurrence and development of heart failure treatment. Various indicators such as Index of Microvascular Resistance, Coronary Flow Reserve, Microvascular Resistance Reserve ...
Shaoxin Chen, Weiqian Ou, Shuguang Gan, Lixian Chen, Baohua Liu, Zhenhong Zhang   +5 more
doaj   +2 more sources

Coronary microcirculation damage in anthracycline cardiotoxicity [PDF]

Cardiovascular Research, 2021
Abstract Aims The aim of this study was to study changes in coronary microcirculation status during and after several cycles of anthracycline treatment. Methods and results Large-white male pigs (n=40) were included in different ...
Carlos Galán-Arriola, Jean Paul Vílchez-Tschischke, Manuel Lobo, Gonzalo J López, Antonio de Molina-Iracheta, Claudia Pérez-Martínez, Rocio Villena-Gutiérrez, Álvaro Macías, Iván A Díaz-Rengifo, Eduardo Oliver, Valentin Fuster, Javier Sánchez-González, Borja Ibanez   +12 more
openaire   +6 more sources

Invasive Assessment of Coronary Microcirculation: A State-of-the-Art Review

Diagnostics, 2023
A significant proportion of patients presenting with signs and symptoms of myocardial ischemia have no “significant” epicardial disease; thereby, the assessment of coronary microcirculation gained an important role in improving diagnosis and guiding ...
Luca Ciaramella, Luigi Di Serafino, Lucia Mitrano, Maria Luisa De Rosa, Carlo Carbone, Francesco Saverio Rea, Salvatore Monaco, Maria Scalamogna, Plinio Cirillo, Giovanni Esposito   +9 more
doaj   +2 more sources

Effects of atherosclerosis on the coronary microcirculation

American Journal of Physiology-Heart and Circulatory Physiology, 1990
We tested the hypothesis that atherosclerosis potentiates coronary vasoconstriction to serotonin and ergonovine. Coronary microvascular pressures and diameters were measured in the beating left ventricle in normal and atherosclerotic cynomolgus monkeys.
W M, Chilian, K C, Dellsperger, S M, Layne, C L, Eastham, M A, Armstrong, M L, Marcus, D D, Heistad   +6 more
openaire   +3 more sources

The coronary microcirculation in hamster-to-rat cardiac xenografts [PDF]

The Thoracic and Cardiovascular Surgeon, 2013
<b><i>Background:</i></b> The aim of this study was to establish a new experimental model to directly analyse the coronary microcirculation in cardiac xenografts. <b><i>Methods:</i></b> Intravital fluorescence microscopy (IVM) of the subepicardial microcirculation in heterotopically transplanted hamster ...
Geiger, Dominik, Buchholz, Stefan, Michel, Sebastian, Abicht, Jan, Reiche, Christoph A., Reichart, Bruno, Hagl, Christian, Brenner, Paolo, Schramm, René   +8 more
openaire   +5 more sources

The Impact of Thrombo‐inflammation on the Cerebral Microcirculation [PDF]

, 2021
Copyright © 2021 The Authors. The intertwined processes of thrombosis and inflammation (termed “thrombo-inflammation”) are significant drivers of cerebrovascular diseases, and as such, they represent prime targets for drug discovery programs focusing on ...
Gavins, FNE, Ansari, J
core   +1 more source

Invasive coronary physiology in patients with angina and non-obstructive coronary artery disease: a consensus document from the coronary microvascular dysfunction workstream of the British Heart Foundation/National Institute for Health Research Partnership [PDF]

, 2022
Nearly half of all patients with angina have non-obstructive coronary artery disease (ANOCA); this is an umbrella term comprising heterogeneous vascular disorders, each with disparate pathophysiology and prognosis.
Rahman, H., Hoole, S.P., Channon, K., UK Coronary Microvascular Dysfunction Working Group, Morris, Paul D, Kharbanda, Rajesh K, Divaka Perera, Channon, K, Petraco, Ricardo, Haseeb Rahman, Hoole, SP, Perera, D., Sinha, Aish, Ricardo Petraco, Keith Channon, Colin Berry, Paul D Morris, Channon, Keith, Stephen P Hoole, Morris, P.D., Hoole, Stephen P, Rajesh K Kharbanda, Rahman, Haseeb, Kharbanda, RK, Hoole, Stephen P., Kharbanda, R.K., Aish Sinha, Petraco, R, Kharbanda, Rajesh K., Perera, Divaka, Sinha, A., Morris, Paul D., Berry, Colin, Berry, C, Morris, PD, Berry, C., Perera, D, Sinha, A, Petraco, R., Rahman, H   +39 more
core   +1 more source

The coronary microcirculation in sepsis: not of micro-importance [PDF]

Global Cardiology Science and Practice, 2020
[No abstract - showing first paragraph]The coronary arterial system consists of a continuous network of functionally distinct vessels of decreasing size. The epicardial arteries (>500 μm) have primarily a conductance function and, therefore, physiologically offer minimal resistance to flow.
Argiro A., Olivotto I.
openaire   +3 more sources

Extended‐volume image‐derived models of coronary microcirculation

, 2023
ObjectiveRecent advances in tissue clearing and high-throughput imaging have enabled the acquisition of extended-volume microvasculature images at a submicron resolution.
Sy, Christine Lauren, Vigneshwaran, Vibujithan, Vibujithan Vigneshwaran, Sands, Gregory B, Christine Lauren Sy, Gregory B. Sands, Bruce H. Smaill, Nicolas P. Smith, Smith, Nicolas P, Smaill, Bruce H   +9 more
core   +1 more source

Vitamin C and Coronary Microcirculation [PDF]

Circulation, 2001
To the Editor: In their study on the short-term effects of vitamin C on coronary microcirculation, Kaufmann et al1 used adenosine to increase myocardial blood flow, which was assessed by positron emission tomography. When compared with controls, smokers showed an attenuated response that was corrected by 3 g of vitamin C given intravenously over 10 ...
S J, Padayatty, M, Levine
openaire   +2 more sources