Results 31 to 40 of about 568,291 (208)
Research progress on the molecular mechanism of coronary microvascular endothelial cell dysfunction
International Journal of Cardiology: Heart & Vasculature, 2021 Coronary microvascular disease is a high-risk factor for many cardiovascular events. However, due to its high concealment and many etiologies, the current understanding of its pathophysiological mechanism is very limited, which greatly limits its ...
Jianying Deng
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Coronary Microvascular Dysfunction: Epidemiology, Clinical Presentation, Diagnosis and Treatment
Рациональная фармакотерапия в кардиологии, 2023 In a significant number of patients with symptoms of angina pectoris or myocardial infarction with ischemic changes in the myocardium, according to the results of instrumental research methods, there is no hemodynamically significant stenosis of the ...
E. L. Trisvetova
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Myocardial injury and coronary microvascular disease in sickle cell disease. [PDF]
Haematologica, 2021 Kaur K +4 more
europepmc +5 more sources
American Heart Journal Plus, 2021 Study objective: The Coronary Vasomotor Disorders International Study Group (COVADIS) invited leading experts to address strategies to enhance our clinical understanding of INOCA with an emphasis on the management of coronary vasomotor disorders. Design:
C. Noel Bairey Merz +13 more
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Endothelium in Coronary Macrovascular and Microvascular Diseases
Journal of Cardiovascular Pharmacology, 2021 Abstract: The endothelium plays a pivotal role in the regulation of vascular tone by synthesizing and liberating endothelium-derived relaxing factors inclusive of vasodilator prostaglandins (eg, prostacyclin), nitric oxide (NO), and endothelium-dependent hyperpolarization factors in a distinct blood vessel size–dependent manner. Large conduit
Godo, Shigeo +3 more
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Indian Journal of Clinical Cardiology, 2021 Chest pain is a common clinical symptom, especially in patients with sickle cell anemia. Owing to the vast differential diagnosis, investigation can be challenging.
Kofi Tekyi Asamoah
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INOCA/ANOCA: Mechanisms and novel treatments
American Heart Journal Plus, 2023 Angina or ischemia with no obstructive coronary disease (ANOCA/INOCA) is a common but under-treated condition due to poorly understood pathophysiologic mechanisms, limited diagnostic tools, and lack of proven targeted therapy.
Namrita D. Ashokprabhu +3 more
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Role of coronary microvascular dysfunction in heart failure with preserved ejection fraction [PDF]
Reviews in Cardiovascular Medicine, 2021 Heart failure with preserved ejection fraction (HFpEF) is one of the greatest unmet needs in modern medicine. The lack of an appropriate therapy may reflect the lack of an accurate comprehension of its pathophysiology.
Francesco Tona +3 more
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Frontiers in Cardiovascular Medicine, 2021 Diabetes is a complex metabolic disease characterized by hyperglycemia. Its complications are various, often involving the heart, brain, kidney, and other essential organs.
Yiming Qi +5 more
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American Heart Journal Plus, 2022 Ischemia with non-obstructive coronary artery disease (INOCA), a common cause of angina, can occur due to coronary vasospasm, microvascular dysfunction, endothelial dysfunction, atherosclerosis or a combination of these mechanisms.
Madhavi Kadiyala +2 more
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