Results 151 to 160 of about 128,004 (314)

Local Production of Soluble Urokinase Plasminogen Activator Receptor and Plasminogen Activator Inhibitor‐1 in the Coronary Circulation Is Associated With Coronary Endothelial Dysfunction in Humans

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018
Background Soluble urokinase plasminogen activator receptor (suPAR) is a proinflammatory biomarker associated with immune activation and fibrinolysis inhibition.
Michel T. Corban, Abhiram Prasad, Lisa Nesbitt, Darrell Loeffler, Joerg Herrmann, Lilach O. Lerman, Amir Lerman   +6 more
doaj   +1 more source

Coronary microvascular dysfunction: mechanisms and functional assessment.

, 2014
| Obstructive disease of the epicardial coronary arteries was recognized as the cause of angina pectoris >2 centuries ago, and sudden thrombotic occlusion of an epicardial coronary artery has been established as the cause of acute myocardial infarction ...
Paolo G. Camici, P. G. Camici, Ornella Rimoldi, D'AMATI, Giulia, Giulia d'Amati, O. Rimoldi   +5 more
core   +1 more source

Olfactory Dysfunction and Metabolic Syndrome Components: A Systematic Review and Meta‐Analysis

The Laryngoscope, EarlyView.
ABSTRACT Objective To elucidate the association between olfactory dysfunction (OD) and metabolic syndrome components. Data Sources PubMed (National Library of Medicine—National Institutes of Health), Scopus (Elsevier), CINAHL Complete (EBSCOhost), and the Cochrane Library (Wiley) databases were searched from inception through March 23rd, 2026.
Neeti Gandra, Kaitlyn A. Roberts, Shaun A. Nguyen, Pete Peters, Lauren A. Howser, Zachary M. Soler, Rodney J. Schlosser   +6 more
wiley   +1 more source

Myocardial Perfusion Defects in Hypertrophic Cardiomyopathy Mutation Carriers

Journal of the American Heart Association, EarlyView., 2021
Background Impaired myocardial blood flow (MBF) in the absence of epicardial coronary disease is a feature of hypertrophic cardiomyopathy (HCM). Although most evident in hypertrophied or scarred segments, reduced MBF can occur in apparently normal segments.
Rebecca K. Hughes, Claudia Camaioni, João B. Augusto, Kristopher Knott, Ellie Quinn, Gabriella Captur, Andreas Seraphim, George Joy, Petros Syrris, Perry M. Elliott, Saidi Mohiddin, Peter Kellman, Hui Xue, Luis R. Lopes, James C. Moon   +14 more
wiley   +1 more source

Unraveling the Shared Genetic Architecture and Molecular Mechanisms Linking Cardiovascular Traits and Glaucoma: A Comprehensive Cross‐Trait Analysis

Medicine Advances, EarlyView.
This study investigates the shared genetic architecture between eight cardiovascular traits and glaucoma using comprehensive cross‐trait analysis. We identified 9948 pleiotropic loci, 71 colocalized signals, and 24 shared genes, with BCAS3, BICC1, FAM213A, ITGB5, NUP160, and TNS1 emerging as robust cross‐trait candidates.
Junfei Huang, Zejun Chen, Mengqing Lin, Bingyu Xu, Qiang Liu, Zhengran Li, Jianping Gao, Guoguo Yi, Min Fu   +8 more
wiley   +1 more source

JCS/CVIT/JCC 2023 Guideline Focused Update on Diagnosis and Treatment of Vasospastic Angina (Coronary Spastic Angina) and Coronary Microvascular Dysfunction.

Circulation Journal, 2023
S. Hokimoto, Koichi Kaikita, S. Yasuda, K. Tsujita, M. Ishihara, T. Matoba, Y. Matsuzawa, Yoshiaki Mitsutake, Y. Mitani, T. Murohara, T. Noda, K. Node, T. Noguchi, Hiroshi Suzuki, J. Takahashi, Y. Tanabe, Atsushi Tanaka, N. Tanaka, H. Teragawa, T. Yasu, M. Yoshimura, Y. Asaumi, Shigeo Godo, Hiroki Ikenaga, T. Imanaka, K. Ishibashi, M. Ishii, T. Ishihara, Y. Matsuura, H. Miura, Y. Nakano, Takayuki Ogawa, T. Shiroto, H. Soejima, Ryu Takagi, A. Tanaka, Atsushi Tanaka, A. Taruya, E. Tsuda, K. Wakabayashi, K. Yokoi, T. Minamino, Y. Nakagawa, S. Sueda, H. Shimokawa, H. Ogawa   +45 more
semanticscholar   +1 more source

Unravelling the pathophysiology of coronary microvascular dysfunction [PDF]

International Journal of Cardiology
Contains fulltext : 315417.pdf (Publisher’s version ) (Open Access)
Crooijmans, C., Damman, P.
openaire   +2 more sources

Staging concept for aging management: Definition, mechanism, and coping strategies

VIEW, EarlyView.
We divided the overall aging stage into “pre‐aging”, “aging compensation”, and “aging disability”. For each stage, we delineate the clinical presentations, biological phenomena, theoretical underpinnings, and key management priorities. Abstract Aging, as a gradual and largely irreversible biological process, characterized by declining organismal ...
Zhonghan Wang, Shixian Liu, Shangyu Du, Xiangran Cui, Bo Chao, Minglei Liu, Minfei Wu   +6 more
wiley   +1 more source

Neurokinin‐1 receptor activation protects against cardiac fibrosis, inflammation and diastolic dysfunction in type 2 diabetic mice

British Journal of Pharmacology, EarlyView.
Background and Purpose The pathogenesis of type 2 diabetes mellitus (T2DM)‐induced cardiomyopathy involves cardiac fibrosis that leads to diastolic dysfunction. We established that replacement of lost substance P (SP) that occurs in T2DM reduces cardiac fibrosis and decreases inflammation in T2DM mice and non‐human primates.
Alexander Widiapradja, Heather Connery, Brody J. Helmick, Kallie J. Schafner, Vamsi Manchikalapudi, Hannah Horvath, Sophia Gugino, Tamas Kriska, Anja Herrnreiter, Evan DeVallance, William B. Campbell, Scott P. Levick   +11 more
wiley   +1 more source

Coronary microvascular dysfunction in the clinical setting: from mystery to reality

, 2012
Far more extensive than the epicardial coronary vasculature that can be visualized angiographically is the coronary microcirculation, which foregoes routine imaging.
Kaski, JC, Lerman, A, Herrmann, J
core   +1 more source