Results 91 to 100 of about 37,384 (259)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Potential of Solar UV Radiation for Inactivation of Coronaviridae Family Estimated from Satellite Data

Photochemistry and Photobiology, 2020
The pandemic COVID‐19 disease affects people dramatically overall the globe by illness and death. Several strategies are applied to restrict the spread of this disease such as lockdown, adequate social distance in different activities, hand disinfection ...
F. Carvalho, D. Henriques, O. Correia, A. Schmalwieser   +3 more
semanticscholar   +1 more source

Differences in virus receptor for type I and type II feline infectious peritonitis virus. [PDF]

, 1998
Feline infectious peritonitis viruses (FIPVs) are classified into type I and type II serogroups. Here, we report that feline aminopeptidase N (APN), a cell-surface metalloprotease on the intestinal, lung and kidney epithelial cells, is a receptor for ...
Hohdatsu, T, Izumiya, Y, Kida, K, Koyama, H, Yokoyama, Y   +4 more
core  

Coronaviridae Study

, 2020
{"references": ["1. Krammer, F. et al. Influenza. Nat. Rev. Dis. Primers 4, 3 (2018).", "2. Zheng, D. P. et al. Norovirus classification and proposed strain nomenclature. Virology 346, 312 - 323 (2006).", "3. Wu, A. et al. Genome composition and divergence of the novel", "5. Gorbalenya, A. E., Lauber, C. & Siddell, S.
Gorbalenya, Alexander E., Baker, Susan C., Baric, Ralph S., de Groot, Raoul J., Drosten, Christian, Gulyaeva, Anastasia A., Haagmans, Bart L., Lauber, Chris, Leontovich, Andrey M., Neuman, Benjamin W., Penzar, Dmitry, Perlman, Stanley, Poon, Leo L. M., Samborskiy, Dmitry V., Sidorov, Igor A., Sola, Isabel, Ziebuhr, John   +16 more
openaire   +1 more source

Nano‐ and Micro‐Sized Solid Materials Used as Antiviral Agents

Advanced Functional Materials, EarlyView.
Due to the rise of viral infections in humans and possible viral outbreaks, the use of nano‐ or micro‐sized materials as antiviral agents is rapidly increasing. This review explores their antiviral properties against RNA and DNA viruses, either as a prevention or a treatment tool, by delving into their mechanisms of action and how to properly assess ...
Orfeas‐Evangelos Plastiras, Imelda Raczkiewicz, Peggy Bouquet, Jean‐Philippe Dacquin, Jeremy Dhainaut, Anne Goffard, Christophe Volkringer   +6 more
wiley   +1 more source

Virus Pathogen Database and Analysis Resource (ViPR): A Comprehensive Bioinformatics Database and Analysis Resource for the Coronavirus Research Community

Viruses, 2012
Several viruses within the Coronaviridae family have been categorized as either emerging or re-emerging human pathogens, with Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) being the most well known.
Yun Zhang, Edward B. Klem, Wei Jen, Richard H. Scheuermann, Christopher N. Larsen, Sam Zaremba, Sanjeev Kumar, Brett E. Pickett, Douglas S. Greer, Zhiping Gu, Guangyu Sun, Liwei Zhou, Lucy Stewart   +12 more
doaj   +1 more source

Coronaviruses Detected in Brazilian Wild Birds Reveal Close Evolutionary Relationships with Beta- and Deltacoronaviruses Isolated From Mammals [PDF]

, 2015
This study showed that the most of the coronaviruses (CoVs) detected in Brazilian wild birds clustered with the mouse hepatitis virus A59 strain, belonging to the BetaCoV group. Furthermore, CoV detected in two different bird species, Amazona vinacea and
Arns, Clarice W, Arns, Clarice W., Barnabé, Ana C. S., Carvalho, Ricardo Duraes de, Caserta, Leonardo C., Felippe, Paulo A. N., Ferreira, Helena L., Martini, Matheus C., Santos, Márcia B.   +8 more
core   +1 more source

Structure‐Based Development of Ultra‐Broad‐Spectrum 3C‐Like Protease Inhibitors

Advanced Science, EarlyView.
This study provides an in‐depth analysis of the substrate binding pocket of 3CLpros across all coronavirus species using bioinformatics and structural insights, revealing the critical impact of S2/S4 subsite diversity on the broad‐spectrum activity of approved therapeutics.
Haixia Su, Tianqing Nie, Guofeng Chen, Muya Xiong, Yumin Zhang, Guoqing Wu, Mengyuan You, Hang Xie, Jian He, Yanchao Xiong, Hangchen Hu, Wenfeng Zhao, Minjun Li, Gengfu Xiao, Leike Zhang, Yechun Xu   +15 more
wiley   +1 more source

Inmunidad pasiva en el control de la diarrea por coronavirus bovino en un rodeo lechero de Argentina [PDF]

, 2018
El coronavirus bovino (Bovine coronavirus, BCoV) es un enteropatógeno viral asociado a la diarrea neonatal del ternero. El objetivo del presente trabajo fue estudiar si los anticuerpos IgG1 anti-BCoV adquiridos pasivamente mediante el calostro modulan la
Allassia, Martín, Bok, Marina, Frank, Flavia, Parreño, Gladys Viviana, Vega, Celina Guadalupe, Wigdorovitz, Andrés   +5 more
core   +2 more sources

Novel Wide‐Spectrum Virucidal Lipid Nanoparticles

Small, EarlyView.
POSTAN is a novel broad‐spectrum antiviral nanoparticle that combines safety with potent virucidal activity. Composed of biocompatible lipids, it mimics heparan sulfate proteoglycans and lipid rafts exploited by viruses, thereby dismantling viral envelopes and blocking replication.
Yugo Araújo Martins, Louise Bondeelle, Arnaud Charles‐Antoine Zwygart, Thais Melquiades de Lima, Juliano de Paula Souza, Han Kang Tee, Fernando Chahud, Eurico de Arruda Neto, Francesco Stellacci, Renata Fonseca Vianna Lopez, Caroline Tapparel   +10 more
wiley   +1 more source