Results 81 to 90 of about 25,596 (197)
ProTides for Antiviral Activity Beyond Liver Cells
Chemistry – A European Journal, Volume 32, Issue 21, 1 June 2026.A strategy for obtaining prodrugs of antiviral nucleotides with broad tissue activity is presented that relies on cycloalkyl or cycloalkylalkyl esters, improving uptake and esterase cleavage, and producing nanomolar inhibitors in kidney, colon, and lung cells.
Felix Goebel +5 more
wiley +1 more source
, 2005 The Coronaviridae are pleomorphic, enveloped, single-stranded RNA viruses with widely spaced, club-shaped projections (after which they are named). The family is not subdivided into genera but instead into antigenic groups.
Paul W. Brazis, MD, Neil R. Miller, MD
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Journal of Medical Virology, Volume 98, Issue 6, June 2026.ABSTRACT Host genetic factors may contribute to COVID‐19 severity. To identify genetic variants influencing COVID‐19 severity progression, whole‐exome sequencing was performed, followed by an exome‐wide association study on 191 hospitalized patients categorized into three severity groups.
Doris Repušić +7 more
wiley +1 more source
, 2021 Aim. The aim of this review is a comprehensive analysis of current literature data on coronaviruses identified in bats. Discussion. Coronaviruses (Coronaviridae) constitute the most extensive family of viruses of the order Nidovirales. Coronaviruses have
Shestopalov A.M.
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Kufa Journal for Veterinary Medical Sciences, 2017 Infectious bronchitis (IB) threatens the economies of entire nations, by adversely affecting the backyard farmers, poultry producers and poultry industry throughout the world.
Mushtaq T. B. AL-Zuhariy
doaj +1 more source
, 2020 — Coronaviruses take the lead in gastrointestinal pathologies of animals and are spread all around the world. Causative agents of coronaviruses belong to Nidovirales order, Coronaviridae family which includes 2 subfamilies: Toroviridna (genera Torovirus ...
Kostarev S. N.
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The evolution of coronaviruses is generally rapid, facilitated by the plasticity of their RNA genomes, and its understanding is essential for interpreting viral diversification and informing evolutionary surveillance.
Luis Daniel González-Vázquez +3 more
core +1 more source
Viruses, 2012 The Coronaviridae family, an enveloped RNA virus family, and, more particularly, human coronaviruses (HCoV), were historically known to be responsible for a large portion of common colds and other upper respiratory tract infections. HCoV are now known to
Mihayl Varbanov +2 more
doaj +1 more source
, 2020 [EN] The present invention relates to new derivatives of 2-phenyl-quinoline-4-carboxylic acid or pharmaceutically acceptable salt thereof and to combination of said compounds with other active ingredients, for use in the treatment and/or prevention of ...
Garaigorta, Urtzi +3 more
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Emergencia zoonótica por coronavirus: riesgo potencial para la salud pública en America Latina.
Revista Mvz Cordoba, 2018 Los coronavirus (CoV) son un grupo de virus de ARN envueltos, monocatenarios (de sentido positivo) que pertenecen al orden Nidovirales, familia Coronaviridae.
Marco González Tous, Salim Mattar V.
doaj +1 more source