Results 61 to 70 of about 25,596 (197)
Coronaviruses are spherical, lipid-containing, enveloped particles with tear-dropshaped surface projections or peplomers. The genome is one molecule of ssRNA and the virions characteristically contain three major structural protein classes. The antigenic relationships of coronaviruses present a complex pattern.
Macnaughton, Malcolm R. +1 more
openaire +2 more sources
An epidemic of COVID-19 (Coronavirus disease 2019) etiologically associated with the SARS-CoV-2 (Severe acute respiratory syndrome-related coronavirus 2) that occurred at the turn of 2019–2020 firstly in Wuhan (Hubei province of China) and then spread to
Shchelkanov M.Yu.
core
Effect of herbal compounds on coronavirus; a systematic review and meta-analysis
Background The new coronavirus (COVID-19) has been transmitted exponentially. Numerous studies have been performed in recent years that have shown the inhibitory effect of plant extracts or plant-derived compounds on the coronavirus family. In this study,
Mina Mobini Kesheh +4 more
doaj +1 more source
ABSTRACT Background and Aims COVID‐19 is an infectious respiratory disease caused by SARS‐CoV‐2. It was first reported in China in 2019 and spread rapidly to the rest of the world, leading to alarming morbidity and mortality. Haematological and biochemical parameters have been used in routine practice as prognostic markers of disease severity. However,
Ackim Munthali +2 more
wiley +1 more source
Development and evaluation of the kit for detection of SARS-associated coronavirus RNA
Aim. To develop a diagnostic kit for detection of SARS (severe acute respiratory syndrome)-related coronavirus RNA based on reverse transcription and polymerase chain reaction and to estimate its specificity and sensitivity. Material and methods.
G A Shipulin +10 more
doaj
Novel coronavirus disease 2019 (COVID-19) is caused by the SARS-CoV-2 virus, which belongs to the genus Coronaviridae with its high mutation rate. From the current perspective, we discuss the current status of COVID-19, new challenges, and potential ...
Faisal Rasheed Anjum +2 more
doaj +1 more source
Given the central role of protein structures in RNA virus biology, the RNA viral protein structure database (RVPSD, https://virus.9itsg.net) integrates taxonomic classification, viral nucleotide and protein sequences, functional annotations, and predicted three‐dimensional protein structures.
Qiangzhen Yang +8 more
wiley +1 more source
Acute appendicitis (AA) is a frequent cause of abdominal pain requiring surgical treatment. During the COVID-19 pandemic, surgical societies considered other therapeutic options due to uncertainties in the evolution of the disease.
JOSÉ GUSTAVO PARREIRA +8 more
doaj +2 more sources
Integrative in silico and in vitro screening of small molecules targeting RNA
Abstract Targeting structured RNA elements with small molecules has emerged as a promising yet technically challenging strategy for antiviral drug discovery. Here, we present a comprehensive and experimentally validated workflow for the integrative in silico and in vitro screening of RNA‐binding small molecules.
Sabrina Toews +2 more
wiley +1 more source
Abstract In less than a year, SARS‐CoV‐2 managed to displace Mycobacterium tuberculosis (Mtb) as the leading cause of death worldwide due to a single infectious agent. Both pathogens affect the respiratory tract, mainly the lungs. However, the impact that a possible Mtb + SARS‐CoV‐2 co‐infection can have on the host response is still unknown. Herein we
Thays Maria Costa de Lucena +7 more
wiley +1 more source

