Results 111 to 120 of about 29,921 (252)
ABSTRACT The objective of this study was to better understand immune failure mechanisms during severe acute respiratory syndrome coronavirus 2, SARS‐CoV‐2 infection, which are critical for developing targeted vaccines and effective treatments. We collected 34 cases representing different disease severities and performed high‐quality single‐cell TCR/BCR
Cong Lai+14 more
wiley +1 more source
The Evolutionary Processes of Canine Coronaviruses [PDF]
Since the first identification of the virus in 1971, the disease caused by canine coronavirus (CCoV) has not been adequately investigated, and the role that the virus plays in canine enteric illness has not been well established. Only after the emergence
Pratelli, Annamaria
core +3 more sources
Biodiversity and epidemic potential of Chiropteran coronaviruses (Nidovirales: Coronaviridae)
Aim. The aim of this review is a comprehensive analysis of current literature data on coronaviruses identified in bats.Discussion. Coronaviruses (Coronaviridae) constitute the most extensive family of viruses of the order Nidovirales.
A. M. Shestopalov+7 more
doaj +1 more source
Detecção rápida do Coronavírus Bovino (BCoV) por meio de uma semi-nested RT-PCR [PDF]
Bovine coronavirus (BCoV) is a member of the group 2 of the Coronavirus (Nidovirales: Coronaviridae) and the causative agent of enteritis in both calves and adult bovine, as well as respiratory disease in calves. The present study aimed to develop a semi-
ASANO, Karen M.+4 more
core +2 more sources
Expression and Purification of SARS‐related Spike Glycoproteins for Cryo‐EM Analysis
Abstract Coronaviridae spike glycoproteins mediate viral entry and fusion to host cells through binding to host receptors (i.e., ACE2, DPP4) and are key components in determining viral host range, making them targets for antiviral research. Here, we describe the expression, purification, and characterization of recombinant spike proteins to aid in ...
Francesca R. Hills+3 more
wiley +1 more source
A New Bat-HKU2–like Coronavirus in Swine, China, 2017
We identified from suckling piglets with diarrhea in China a new bat-HKU2–like porcine coronavirus (porcine enteric alphacoronavirus). The GDS04 strain of this coronavirus shares high aa identities (>90%) with the reported bat-HKU2 strains in ...
Lang Gong+8 more
doaj +1 more source
Transmissible gastroenteritis virus: Identification of M protein-binding peptide ligands with antiviral and diagnostic potential [PDF]
The membrane (M) protein is one of the major structural proteins of coronavirus particles. In this study, the M protein of transmissible gastroenteritis virus (TGEV) was used to biopan a 12-mer phage display random peptide library.
Ren, Xiaofeng+4 more
core +1 more source
The veterinary perspective of COVID-19 [PDF]
Coronaviridae is a family of RNA viruses responsible for two previous epidemics of viral pneumonia and related illnesses: Severe Acute Respiratory Syndrome in 2002 and Middle East Respiratory Syndrome in 2012. The current COVID-19 pandemic is caused by a
Lawal, N., Onoja, A.B.
core +2 more sources
Human Coronavirus-229E, -OC43, -NL63, and -HKU1 (Coronaviridae)
Seven human coronaviruses (HCoVs) have been so far identified, namely HCoV-229E, HCoV-OC43, HCoV-NL63, HCoV-HKU1, severe acute respiratory syndrome coronavirus (SARS-CoV), Middle East respiratory syndrome coronavirus (MERS-CoV) and the novel coronavirus (2019-nCoV, a.k.a. SARS-CoV-2).
Liu, Ding X., Liang, Jia Q., Fung, To S.
openaire +2 more sources
Psychological and Burnout Effects of the COVID‐19 Pandemic on Individuals
ABSTRACT Background COVID‐19 infection has affected individuals mentally and socially in many areas. Restrictions, fear of infection, and anxiety about the future have created a great psychological burden on people. In this study, we aimed to investigate the significant negative effects of the COVID‐19 pandemic on individuals' mental health and ...
Bahar Ürün Ünal+4 more
wiley +1 more source