Results 111 to 120 of about 37,384 (259)

Simulate_PCR for amplicon prediction and annotation from multiplex, degenerate primers and probes [PDF]

open access: yes, 2014
BACKGROUND: Pairing up primers to amplify desired targets and avoid undesired cross reactions can be a combinatorial challenge. Effective prediction of specificity and inclusivity from multiplexed primers and TaqMan®/Luminex® probes is a critical step in
Shea N Gardner, Tom Slezak
core   +2 more sources

Advances in Microbial Diagnostics: Machine Learning and Nanotechnology for Zoonotic Disease Control

open access: yesWIREs Nanomedicine and Nanobiotechnology, Volume 18, Issue 1, January/February 2026.
This review highlights how integrating machine learning with nanotechnology enables enhanced diagnostics, personalized treatments, and the prediction of outbreaks for zoonotic diseases, offering a unified framework to advance global health. ABSTRACT Zoonotic diseases pose significant global health threats, with microbial pathogens, including bacteria ...
Narges Lotfalizadeh   +8 more
wiley   +1 more source

Protein Nucleotidylylation in +ssRNA Viruses

open access: yesViruses, 2021
Nucleotidylylation is a post-transcriptional modification important for replication in the picornavirus supergroup of RNA viruses, including members of the Caliciviridae, Coronaviridae, Picornaviridae and Potyviridae virus families.
Alice-Roza Eruera   +3 more
doaj   +1 more source

Viable porcine arteriviruses with deletions proximal to the 3 ' end of the genome [PDF]

open access: yes, 2001
In order to obtain attenuated live vaccine candidates of porcine reproductive and respiratory syndrome virus (PRRSV), a series of deletions was introduced at the 3′ end of the viral genome using an infectious cDNA clone of the Lelystad virus isolate. RNA
Kroese, M.V.   +3 more
core   +2 more sources

Bridging Genomics and Clinical Medicine: RSVrecon Enhances RSV Surveillance With Automated Genotyping and Clinically Important Mutation Reporting

open access: yesInfluenza and Other Respiratory Viruses, Volume 20, Issue 1, January 2026.
ABSTRACT Background Respiratory Syncytial Virus (RSV) causes significant respiratory infections, particularly in young children and elderly adults. Genetic variations in the fusion (F) protein can reduce the efficacy of vaccination and monoclonal antibody treatments, emphasizing the need for genomic surveillance of this virus.
Lei Li   +6 more
wiley   +1 more source

“Identification and enrichment of SECReTE cis-acting RNA elements in the Coronaviridae and other (+) single-strand RNA viruses”

open access: yesbioRxiv, 2020
cis-acting RNA motifs play a major role in regulating many aspects of RNA biology including posttranscriptional processing, nuclear export, RNA localization, translation and degradation.
Gal Haimovich   +3 more
semanticscholar   +1 more source

Transmissible gastroenteritis virus: Identification of M protein-binding peptide ligands with antiviral and diagnostic potential [PDF]

open access: yes, 2013
The membrane (M) protein is one of the major structural proteins of coronavirus particles. In this study, the M protein of transmissible gastroenteritis virus (TGEV) was used to biopan a 12-mer phage display random peptide library.
Ren, Xiaofeng   +4 more
core   +1 more source

The role of cellular adhesion molecules in virus attachment and entry [PDF]

open access: yes, 2015
As obligate intracellular parasites, viruses must traverse the host-cell plasma membrane to initiate infection. This presents a formidable barrier, which they have evolved diverse strategies to overcome.
Bhella, David
core   +1 more source

Prevention of Porcine Epidemic Diarrhea Virus With Nanotube‐Adjuvanted Oral DNA Vaccines

open access: yesTransboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Porcine epidemic diarrhea virus (PEDV) causes severe diarrhea in piglets. The ideal route of protection against PEDV for piglets is through passive (lactogenic) immunity, which is not provided by current inactivated and subunit vaccines on the market. In this study, we investigated whether a DNA vaccine encoding the full PEDV spike protein adjuvanted ...
Hsing-Chieh Wu   +8 more
wiley   +1 more source

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