Results 51 to 60 of about 29,921 (252)

In vitro and in vivo expression of foreign genes by transmissible gastroenteritis coronavirus-derived minigenomes [PDF]

open access: yes, 2002
A helper-dependent expression system based on transmissible gastroenteritis coronavirus (TGEV) has been developed using a minigenome of 3·9 kb (M39).
Alonso, S.   +8 more
core   +8 more sources

Inhibition of glycogen synthase kinase-3-beta (GSK3β) blocks nucleocapsid phosphorylation and SARS-CoV-2 replication

open access: yesMolecular Biomedicine, 2022
GSK3β has been proposed to have an essential role in Coronaviridae infections. Screening of a targeted library of GSK3β inhibitors against both SARS-CoV-2 and HCoV-229E to identify broad-spectrum anti-Coronaviridae inhibitors resulted in the ...
Tirosh Shapira   +12 more
doaj   +1 more source

Protease inhibitors targeting coronavirus and filovirus entry. [PDF]

open access: yes, 2015
In order to gain entry into cells, diverse viruses, including Ebola virus, SARS-coronavirus and the emerging MERS-coronavirus, depend on activation of their envelope glycoproteins by host cell proteases.
Agudelo, Juliet   +10 more
core   +1 more source

A phage-displayed peptide recognizing porcine aminopeptidase N is a potent small molecule inhibitor of PEDV entry [PDF]

open access: yes, 2014
Three phage-displayed peptides designated H, S and F that recognize porcine aminopeptidase N (pAPN), the cellular receptor of porcine transmissible gastroenteritis virus (TGEV) were able to inhibit cell infection by TGEV.
Cong, Yingying   +6 more
core   +2 more sources

The pulmonary-proteoliposome as a new therapeutic approach for Coronaviruses [PDF]

open access: yes, 2020
We are proposing the use of pulmonary-proteoliposome as a new therapeutic approach for Coronaviruses. The designed strategy represents a potential treatment to reduce the overall viral load in the lungs and to help the immune system to successfully stave
Feliciello, Isidoro, Procino, Alfredo
core   +1 more source

Coronaviruses: modern taxonomy and research chronology

open access: yesНауковий вісник Львівського національного університету ветеринарної медицини та біотехнологій імені С.З. Ґжицького: Серія Ветеринарні науки, 2022
The classification of coronaviruses began in 1968 when five viruses (IBV, MHV, B814, 229E, and OC43) were united into an independent group, “coronaviruses”, based on the characteristic morphology of the virions. In 1971, the genus Coronavirus was formed,
O. S. Kalinina, I. K. Avdosieva
doaj   +1 more source

Ratification vote on taxonomic proposals to the International Committee on Taxonomy of Viruses (2016) [PDF]

open access: yes, 2016
This article lists the changes to virus taxonomy approved and ratified by the International Committee on Taxonomy of Viruses (ICTV) in April 2016. Changes to virus taxonomy (the Universal Scheme of Virus Classification of the International Committee on ...
Adams, Michael J.   +18 more
core   +4 more sources

Convolutional Neural Network Applied to SARS-CoV-2 Sequence Classification [PDF]

open access: yes, 2022
COVID-19, the illness caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus belonging to the Coronaviridade family, a single-strand positive-sense RNA genome, has been spreading around the world and has been declared a pandemic
Câmara, Gabriel B. M.   +1 more
core   +1 more source

Database of SARS-CoV-2 and coronaviruses kinetics relevant for assessing persistence in food processing plants

open access: yesScientific Data, 2022
Measurement(s) Decimal reduction time Technology Type(s) Modelling of kinetics Factor Type(s) Temperature • Relative humidity • Genus • Strain Sample Characteristic - Organism ...
Ngoc-Du Martin Luong   +7 more
doaj   +1 more source

Molecular Basis of the Structure and Transmission of SARS-CoV, SARS-CoV-2, and MERS: A Review Report

open access: yesBioscientific Review, 2023
In late 2019, a new coronaviridae family member officially designated as “Severe Acute Respiratory Syndrome Coronavirus-2” (SARS-CoV-2) emerged and began to spread intensely, worldwide.
Dr. Saima Naz   +3 more
doaj   +1 more source

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