Feline coronavirus drug inhibits the main protease of SARS-CoV-2 and blocks virus replication
Nature Communications, 2020 Coronavirus main protease is essential for viral polyprotein processing and replication. Here Vuong et al. report efficient inhibition of SARS-CoV-2 replication by the dipeptide-based protease inhibitor GC376 and its parent GC373, which were originally ...
Wayne Vuong +13 more
doaj +1 more source
Peptides corresponding to the predicted heptad repeat 2 domain of the feline coronavirus spike protein are potent inhibitors of viral infection. [PDF]
PLoS ONE, 2013 BACKGROUND: Feline infectious peritonitis (FIP) is a lethal immune-mediated disease caused by feline coronavirus (FCoV). Currently, no therapy with proven efficacy is available.
I-Jung Liu +3 more
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A review of coronavirus infection in the central nervous system of cats and mice. [PDF]
, 2001 Feline infectious peritonitis (FIP) is a common cause of death in cats. Management of this disease has been hampered by difficulties identifying the infection and determining the immunological status of affected cats and by high variability in the ...
Foley, JE, Leutenegger, C
core
Recombinant feline coronaviruses as vaccine candidates confer protection in SPF but not in conventional cats [PDF]
, 2014 Feline infectious peritonitis virus (FIPV) is a major pathogen of Felidae. Despite the extensive efforts taken in the past decades, development of the "ideal" live attenuated FIPV vaccine was not successful yet.
Balint, Adam +4 more
core +1 more source
Cohorts of immature Pteropus bats show interannual variation in Hendra virus serology
Journal of Animal Ecology, Volume 95, Issue 3, Page 521-537, March 2026.Pteropus bat with offspring, photo taken by Manuel Ruiz‐Aravena. Abstract Understanding the drivers of seasonal disease outbreaks remains a fundamental challenge in disease ecology. Periodic outbreaks can be driven by several seasonally varying factors, including pulses of susceptible individuals through births, changes in host behaviour and social ...
Daniel E. Crowley +24 more
wiley +1 more source
Serosurvey of mountain lions in southern Arizona
Wildlife Society Bulletin, 2012 An understanding of the prevalence of diseases in free‐ranging populations of felids is limited, and there is even less known about the overall health and diseases of wild felids that inhabit or utilize urban areas.
Kerry L. Nicholson +2 more
doaj +1 more source
Diagnosis of some diseases through biomarkers [PDF]
, 2019 Muchos gatos, como los perros, sufren de diferentes enfermedades. que en ese momento no permiten mostrar síntomas o signos que permiten identificar que la mascota sufre una enfermedad grave, ya que las características de los gatos son diferentes a las de
Gutiérrez Rodríguez, Andrea
core
Structure‐Based Development of Ultra‐Broad‐Spectrum 3C‐Like Protease Inhibitors
Advanced Science, Volume 13, Issue 11, 23 February 2026.This study provides an in‐depth analysis of the substrate binding pocket of 3CLpros across all coronavirus species using bioinformatics and structural insights, revealing the critical impact of S2/S4 subsite diversity on the broad‐spectrum activity of approved therapeutics.
Haixia Su +15 more
wiley +1 more source
The Paradox of Feline Coronavirus Pathogenesis: A Review [PDF]
Advances in Virology, 2011 Feline coronavirus (FCoV) is an enveloped single-stranded RNA virus, of the familyCoronaviridaeand the orderNidovirales. FCoV is an important pathogen of wild and domestic cats and can cause a mild or apparently symptomless enteric infection, especially in kittens.
Luciana Wanderley Myrrha +5 more
openaire +3 more sources
Application of versatile reverse genetics system for feline coronavirus
Microbiology SpectrumFeline infectious peritonitis (FIP) is a fatal disease caused by feline coronavirus (FCoV). Although multiple gene mutations in FCoV likely account for FIP pathogenesis, molecular studies for FCoV have been limited due to the lack of a suitable reverse ...
Izumi Kida +5 more
doaj +1 more source