Results 1 to 10 of about 2,257 (148)

Identification of a novel N-terminal linear B-cell epitope on the FIPV nucleocapsid protein by a monoclonal antibody [PDF]

BMC Veterinary Research
Background Feline infectious peritonitis (FIP) is difficult to diagnose in clinical practice and has a high mortality rate, which underscores the need for reliable and standardized diagnostic tools.
Feiyu Zhao, Xiaoxi Yu, Weiyue Jiang, Yingying Cao, Zhen Li, Haixin Liu, Dongbo Sun   +6 more
doaj   +3 more sources

Characterization of antiviral T cell responses during primary and secondary challenge of laboratory cats with feline infectious peritonitis virus (FIPV) [PDF]

BMC Veterinary Research, 2019
Background Feline infectious peritonitis (FIP) is considered highly fatal in its naturally occurring form, although up to 36% of cats resist disease after experimental infection, suggesting that cats in nature may also resist development of FIP in the ...
Ellen Sparger, , Farina Mustaffa-Kamal
exaly   +7 more sources

Ursodeoxycholic acid inhibits feline infectious peritonitis virus infection through activating JAK-STAT signaling pathway-induced type I interferon [PDF]

Microbiology Spectrum
Feline infectious peritonitis virus (FIPV), a highly pathogenic subtype of feline coronavirus, is characterized by antigenic variability and immune evasion, resulting in limited efficacy of existing clinical therapeutic regimens.
Yi Zhong, Zhiwei Sun, Ziyan Song, Jinman Ding, Yanwen Song, Yi Li, Guisong Liao, Xin Wang, Yan Zeng, Nan Hu, Xingcui Zhang, Zhenhui Song   +11 more
doaj   +2 more sources

The ORF1ab of Feline Coronavirus Plays a Critical Role in Regulating the Innate Immune Response [PDF]

Viruses
Feline coronaviruses (FCoVs) are divided into two groups: feline infectious peritonitis virus (FIPV) and feline enteric coronavirus (FECV). FIPV is responsible for the severe disease known as feline infectious peritonitis, while FECV typically causes ...
Haorong Gu, Chuqiao Xia, Hongtao Kang, Honglin Jia   +3 more
doaj   +2 more sources

Identification of potential inhibitors of the main protease from feline infectious peritonitis virus using molecular docking and dynamic simulation approaches [PDF]

PeerJ
Background Feline infectious peritonitis virus (FIPV) is one of cats’ most serious viral infections. The FIPV infection induces a complicated syndrome in the affected cats, including immunosuppression and severe inflammatory conditions.
Mohd Yasir Khan, Abid Ullah Shah, Nithyadevi Duraisamy, Nadine Moawad, Reda Nacif ElAlaoui, Mohammed Cherkaoui, Maged Gomaa Hemida   +6 more
doaj   +3 more sources

Antiviral and Immunomodulatory Effects of α-Mangostin Against Feline Infectious Peritonitis Virus: In Vitro Assay [PDF]

Animals
Feline infectious peritonitis virus (FIPV), caused by a mutated form of feline coronavirus, poses a significant threat to feline health worldwide, with limited therapeutic options available. This study investigated the antiviral potential of α-mangostin (
Varanya Lueangaramkul, Pratipa Termthongthot, Natjira Mana, Pharkphoom Panichayupakaranant, Ploypailin Semkum, Porntippa Lekcharoensuk, Sirin Theerawatanasirikul   +6 more
doaj   +2 more sources

Immune Cell Signaling in Feline Infectious Peritonitis Virus Infection and Implications for Vaccine Design [PDF]

Vaccines
Feline infectious peritonitis virus (FIPV) remains one of the most challenging viral diseases in veterinary medicine, largely owing to the absence of a consistently effective and safe vaccine.
Hye-Mi Lee
doaj   +2 more sources

Comparative Genome Sequencing Analysis of Some Novel Feline Infectious Peritonitis Viruses Isolated from Some Feral Cats in Long Island [PDF]

Viruses
Feline infectious peritonitis virus (FIPV) remains as one of the leading causes of morbidity and mortality in young cats from shelters and catteries worldwide.
Abid Ullah Shah, Blanca Esparza, Oscar Illanes, Maged Gomaa Hemida   +3 more
doaj   +2 more sources

Evaluation of the Dual Antiviral and Immunomodulatory Effects of Phallus indusiatus in a Feline Infectious Peritonitis Model Using PBMCs [PDF]

Veterinary Sciences
Feline infectious peritonitis (FIP) is a progressive and often fatal disease caused by a virulent biotype of feline coronavirus (FCoV). Although antiviral treatments are now available, relapse and resistance remain ongoing concerns.
Chularat Hlaoperm, Wassamon Moyadee, Emwalee Wongsaengnoi, Wiwat Klankaew, Amonpun Rattanasrisomporn, Atchara Paemanee, Kiattawee Choowongkomon, Oumaporn Rungsuriyawiboon, Jatuporn Rattanasrisomporn   +8 more
doaj   +2 more sources

Evaluating the Impact of Needle-Free Delivery of Inactivated Polio Vaccine on Nigeria’s Routine Immunization Program: An Implementation Hybrid Trial [PDF]

Vaccines
Background/Objectives: The Tropis® ID device (PharmaJet®), a needle-free injection system, is a World Health Organization prequalified, hand-held device, which delivers intradermal injections without the use of needles and has previously been used for ...
Diwakar Mohan, Mercy Mvundura, Sidney Sampson, Victor Abiola Adepoju, Garba Bello Bakunawa, Chidinma Umebido, Adachi Ekeh, Joe Little, Catherine Daly, Christopher Morgan, Sunday Atobatele, Paul LaBarre, Elizabeth Oliveras   +12 more
doaj   +2 more sources