Viruses, 2022 Feline infectious peritonitis (FIP) is a disease of domestic cats caused by the genetic variant of the feline coronavirus (FCoV) and feline infectious peritonitis virus (FIPV), currently grouped into two serotypes, I and II.
Sarah Cook +2 more
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Ursodeoxycholic acid inhibits feline infectious peritonitis virus infection through activating JAK-STAT signaling pathway-induced type I interferon [PDF]
Microbiology SpectrumFeline infectious peritonitis virus (FIPV), a highly pathogenic subtype of feline coronavirus, is characterized by antigenic variability and immune evasion, resulting in limited efficacy of existing clinical therapeutic regimens.
Yi Zhong +11 more
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The ORF1ab of Feline Coronavirus Plays a Critical Role in Regulating the Innate Immune Response [PDF]
VirusesFeline coronaviruses (FCoVs) are divided into two groups: feline infectious peritonitis virus (FIPV) and feline enteric coronavirus (FECV). FIPV is responsible for the severe disease known as feline infectious peritonitis, while FECV typically causes ...
Haorong Gu +3 more
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Identification of potential inhibitors of the main protease from feline infectious peritonitis virus using molecular docking and dynamic simulation approaches [PDF]
PeerJBackground Feline infectious peritonitis virus (FIPV) is one of cats’ most serious viral infections. The FIPV infection induces a complicated syndrome in the affected cats, including immunosuppression and severe inflammatory conditions.
Mohd Yasir Khan +6 more
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Comparative in vivo analysis of recombinant type II feline coronaviruses with truncated and completed ORF3 region. [PDF]
PLoS ONE, 2014 Our previous in vitro comparative study on a feline coronavirus (FCoV) pair, differing only in the intactness of their ORF3abc regions, showed that the truncated ORF3abc plays an important role in the efficient macrophage/monocyte tropism of type II ...
Ádám Bálint +3 more
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Antiviral and Immunomodulatory Effects of α-Mangostin Against Feline Infectious Peritonitis Virus: In Vitro Assay [PDF]
AnimalsFeline infectious peritonitis virus (FIPV), caused by a mutated form of feline coronavirus, poses a significant threat to feline health worldwide, with limited therapeutic options available. This study investigated the antiviral potential of α-mangostin (
Varanya Lueangaramkul +6 more
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Immune Cell Signaling in Feline Infectious Peritonitis Virus Infection and Implications for Vaccine Design [PDF]
VaccinesFeline infectious peritonitis virus (FIPV) remains one of the most challenging viral diseases in veterinary medicine, largely owing to the absence of a consistently effective and safe vaccine.
Hye-Mi Lee
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Evaluation of the Dual Antiviral and Immunomodulatory Effects of Phallus indusiatus in a Feline Infectious Peritonitis Model Using PBMCs [PDF]
Veterinary SciencesFeline infectious peritonitis (FIP) is a progressive and often fatal disease caused by a virulent biotype of feline coronavirus (FCoV). Although antiviral treatments are now available, relapse and resistance remain ongoing concerns.
Chularat Hlaoperm +8 more
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Association Study on Risk Factors for Major Infectious Diseases in Dogs and Cats in Shenzhen, China [PDF]
AnimalsThis study investigated the prevalence of 11 common pathogens in dogs and cats in Shenzhen, China, from January 2022 to March 2024, aiming to enhance the understanding of their epidemiological characteristics for improved disease control strategies ...
Yao Peng +10 more
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Comparative Genome Sequencing Analysis of Some Novel Feline Infectious Peritonitis Viruses Isolated from Some Feral Cats in Long Island [PDF]
VirusesFeline infectious peritonitis virus (FIPV) remains as one of the leading causes of morbidity and mortality in young cats from shelters and catteries worldwide.
Abid Ullah Shah +3 more
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