Results 21 to 30 of about 3,798 (191)

Coronavirus Nsp3 Hijacks CLTC to Modulate Autophagosome Nucleation for Promoting DMV Formation and Viral Replication. [PDF]

Adv Sci (Weinh)
In wild‐type cells, FIPV infection recruits CLTC to nsp3, facilitates DMV biogenesis and block autophagic flux to promote viral replication. CLTC knockout impairs autophagosome nucleation by reducing Beclin1–ATG14 complex expression. This disrupts the formation of autophagic precursor membranes, thereby preventing their hijacking by nsp3 for DMV ...
Xu J, Li H, Liu P, Jiao Z, Zhang D, Su Z, Niu S, Zhang J, Shi Y, Peng G.   +9 more
europepmc   +2 more sources

Beyond macrophages: FIPV tropism includes T and B lymphocytes. [PDF]

Vet Microbiol
If untreated, feline infectious peritonitis (FIP) is a fatal disease that is caused by feline infectious peritonitis virus (FIPV), a virulent biotype of feline coronavirus (FCoV) that disseminates broadly and triggers severe systemic inflammation. While the prevailing model holds that FIPV selectively infects monocytes/macrophages, the full range of ...
Balakumar A, Wanakumjorn P, Kimura K, McLarty E, Farrell K, Brostoff T, Pires J, Cohen-Davidyan T, Cassano JM, Murphy B, Reagan K, Kol A.   +11 more
europepmc   +3 more sources

First study on in vitro antiviral and virucidal effects of flavonoids against feline infectious peritonitis virus at the early stage of infection [PDF]

Veterinary World, 2023
Background and Aim: Feline infectious peritonitis (FIP), one of the most important infectious diseases in cats is caused by FIP virus (FIPV), a mutated variant of feline coronavirus.
Chanittha Triratapiban, Varanya Lueangaramkul, Nantawan Phecharat, Achiraya Pantanam, Porntippa Lekcharoensuk, Sirin Theerawatanasirikul   +5 more
doaj   +1 more source

Achieving high immunogenicity against poliovirus with fractional doses of inactivated poliovirus vaccine in Ecuador-results from a cross-sectional serological survey

The Lancet Regional Health. Americas, 2022
Summary: Background: In January 2018, Ecuador changed its routine immunization schedule by replacing one full dose of inactivated poliovirus vaccine (IPV) administered intramuscularly at 2 months of age with two doses of fractional IPV (1/5th of full ...
Gabriel Trueba, Vishali Jeyaseelan, Lazaro Lopez, Bernardo A. Mainou, Yiting Zhang, Alvaro Whittembury, Alfredo Jose Olmedo Valarezo, Gonzalo Baquero, Rosa Romero de Aguinaga, Lucia Jeannete Zurita Salinas, Maria Gabriela Santacruz Mancheno, Diana Elizabeth Medina Chacho, Emmanuelle Quentin, Ana Elena Chevez, Gloria Rey-Benito, Ondrej Mach   +15 more
doaj   +1 more source

Possible Antiviral Activity of 5-Aminolevulinic Acid in Feline Infectious Peritonitis Virus (Feline Coronavirus) Infection

Frontiers in Veterinary Science, 2021
Feline infectious peritonitis (FIP) is a life-threatening infectious disease of cats caused by virulent feline coronavirus (FIP virus: FIPV). For the treatment of FIP, several effective antivirals were recently reported, but many of these are not ...
Tomomi Takano, Kumi Satoh, Tomoyoshi Doki   +2 more
doaj   +1 more source

Successful in vitro propagation of feline coronavirus from clinically diagnosed feline infectious peritonitis cases using Vero cells: A potential model for future research. [PDF]

Vet Rec Open
Abstract Background Feline coronavirus (FCoV) causes inapparent to progressive fatal feline infectious peritonitis (FIP) in domestic and wild cats, which affects multiple‐organ systems. Methods We investigated three clinically sick cats using different laboratory and molecular tests to diagnose and confirm FCoV and propagate the virus in Vero cell ...
Rana EA, Akther M, Beetson S, Sarker S, Rossi G, Uddin JM.   +5 more
europepmc   +2 more sources

Design Strategies for Façade integrated Photovoltaic Technology (FiPV)

Proceedings of the International Conference of Contemporary Affairs in Architecture and Urbanism-ICCAUA, 2022
The rapid pace of urbanisation has caused a surge in the energy demand, thus emphasizing the need for Net Zero Energy buildings. A plethora of financial and non-financial incentives for promoting energy efficient and renewable energy buildings are being offered by several local governments in India.
Mariam Ahmad, Hina Zia
openaire   +2 more sources

ERDRP-0519 inhibits feline coronavirus in vitro

BMC Veterinary Research, 2022
Background Coronaviruses (CoVs) are major human and animal pathogens and antiviral drugs are pursued as a complementary strategy, chiefly if vaccines are not available.
Michele Camero, Gianvito Lanave, Cristiana Catella, Maria Stella Lucente, Alessio Sposato, Viviana Mari, Maria Tempesta, Vito Martella, Alessio Buonavoglia   +8 more
doaj   +1 more source

Phylogenetic analysis of feline infectious peritonitis virus, feline enteric coronavirus, and severe acute respiratory syndrome coronavirus 2 of cats in Surabaya, Indonesia [PDF]

Veterinary World, 2023
Background and Aim: Questions about the origin of coronavirus and its introduction to human beings have persisted. The detection of a variety of coronavirus related to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in bats and pangolins led
Eduardus Bimo Aksono, Kania Rifa Iradatya, Teguh Hari Sucipto, Nur Syamsiatul Fajar, Wiwik Misaco Yuniarti   +4 more
doaj   +1 more source

An experience of mass administration of fractional dose inactivated polio vaccine through intradermal needle-free injectors in Karachi, Sindh, Pakistan

BMC Public Health, 2021
Background Inactivated Polio Vaccine (IPV) campaign was conducted in February 2019 in Karachi where needle-free injectors were introduced for the administration of the fractional dose of IPV (fIPV) on a large scale.
Umar Farooq Bullo, Jaishri Mehraj, Syed Musa Raza, Shumaila Rasool, Noreen Naz Ansari, Ahmed Ali Shaikh, Zamir Ali Phul, Sohail Ahmed Memon, Rehan Iqbal Baloch, Zahoor Ahmed Baloch, Shoukat Ali Chandio   +10 more
doaj   +1 more source