Results 41 to 50 of about 2,244 (118)

Mutation in Spike Protein Cleavage Site and Pathogenesis of Feline Coronavirus

Emerging Infectious Diseases, 2013
Feline coronaviruses (FCoV) exist as 2 biotypes: feline enteric coronavirus (FECV) and feline infectious peritonitis virus (FIPV). FECV causes subclinical infections; FIPV causes feline infectious peritonitis (FIP), a systemic and fatal disease.
Beth N. Licitra, Jean K. Millet, Andrew D. Regan, Brian S. Hamilton, Vera D. Rinaldi, Gerald E. Duhamel, Gary R. Whittaker   +6 more
doaj   +1 more source

Successful in vitro propagation of feline coronavirus from clinically diagnosed feline infectious peritonitis cases using Vero cells: A potential model for future research

Veterinary Record Open, Volume 13, Issue 1, June 2026.
Abstract Background Feline coronavirus (FCoV) causes inapparent to progressive fatal feline infectious peritonitis (FIP) in domestic and wild cats, which affects multiple‐organ systems. Methods We investigated three clinically sick cats using different laboratory and molecular tests to diagnose and confirm FCoV and propagate the virus in Vero cell ...
Eaftekhar Ahmed Rana, Mahfuza Akther, Susan Beetson, Subir Sarker, Gabriele Rossi, Jasim M. Uddin   +5 more
wiley   +1 more source

Evaluating the cost per child vaccinated with full versus fractional-dose inactivated poliovirus vaccine

Vaccine: X, 2019
Introduction: Inactivated poliovirus vaccine (IPV) shortages and evidence of improved immunogenicity of two intradermal (ID) fractional IPV (fIPV) doses compared with one full intramuscular dose led to recommendations for fIPV delivery.
Mercy Mvundura, Jui-Shan Hsu, Collrane Frivold, Debra Kristensen, Shanda Boyle, Darin Zehrung, Courtney Jarrahian   +6 more
doaj   +1 more source

Nano‐ and Micro‐Sized Solid Materials Used as Antiviral Agents

Advanced Functional Materials, Volume 36, Issue 26, 30 March 2026.
Due to the rise of viral infections in humans and possible viral outbreaks, the use of nano‐ or micro‐sized materials as antiviral agents is rapidly increasing. This review explores their antiviral properties against RNA and DNA viruses, either as a prevention or a treatment tool, by delving into their mechanisms of action and how to properly assess ...
Orfeas‐Evangelos Plastiras, Imelda Raczkiewicz, Peggy Bouquet, Jean‐Philippe Dacquin, Jeremy Dhainaut, Anne Goffard, Christophe Volkringer   +6 more
wiley   +1 more source

An Optimized Bioassay for Screening Combined Anticoronaviral Compounds for Efficacy against Feline Infectious Peritonitis Virus with Pharmacokinetic Analyses of GS-441524, Remdesivir, and Molnupiravir in Cats

Viruses, 2022
Feline infectious peritonitis (FIP) is a fatal disease of cats that currently lacks licensed and affordable vaccines or antiviral therapeutics. The disease has a spectrum of clinical presentations including an effusive (“wet”) form and non-effusive (“dry”
Sarah Cook, Luke Wittenburg, Victoria C. Yan, Jacob H. Theil, Diego Castillo, Krystle L. Reagan, Sonyia Williams, Cong-Dat Pham, Chun Li, Florian L. Muller, Brian G. Murphy   +10 more
doaj   +1 more source

Structure‐Based Development of Ultra‐Broad‐Spectrum 3C‐Like Protease Inhibitors

Advanced Science, Volume 13, Issue 11, 23 February 2026.
This study provides an in‐depth analysis of the substrate binding pocket of 3CLpros across all coronavirus species using bioinformatics and structural insights, revealing the critical impact of S2/S4 subsite diversity on the broad‐spectrum activity of approved therapeutics.
Haixia Su, Tianqing Nie, Guofeng Chen, Muya Xiong, Yumin Zhang, Guoqing Wu, Mengyuan You, Hang Xie, Jian He, Yanchao Xiong, Hangchen Hu, Wenfeng Zhao, Minjun Li, Gengfu Xiao, Leike Zhang, Yechun Xu   +15 more
wiley   +1 more source

Molecular and Clinical Screening of Selected Feline Viral Infections in Sulaymaniyah, Kurdistan Region, Iraq

Advances in Virology, Volume 2026, Issue 1, 2026.
This study presents a new molecular epidemiology dataset on the prevalence of selected viral pathogens, including Feline panleukopenia virus (FPV), feline calicivirus (FCV), and feline coronavirus (FCoV) (systemic feline infectious peritonitis [FIP]), in domestic cats in Sulaymaniyah, Kurdistan region, Iraq.
Sirwan Sleman, Basm Ali, Zaniar A. Abass, Barham J. Abdullah, Omed I. Abid, Masood B. Ameen, Rand Swara, Ali Sirwan, Jasbir Arora   +8 more
wiley   +1 more source

Characterization of antiviral T cell responses during primary and secondary challenge of laboratory cats with feline infectious peritonitis virus (FIPV)

BMC Veterinary Research, 2019
Background Feline infectious peritonitis (FIP) is considered highly fatal in its naturally occurring form, although up to 36% of cats resist disease after experimental infection, suggesting that cats in nature may also resist development of FIP in the ...
Farina Mustaffa-Kamal, Hongwei Liu, Niels C. Pedersen, Ellen E. Sparger   +3 more
doaj   +1 more source

Recent Advances in Lateral Flow Immunoassay for Rapid Diagnosis of Viral Diseases

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Viral diseases are a major threat to human and animal health, as illustrated by recent pandemics like COVID‐19 and African swine fever (ASF). Timely, accurate detection of viral infections is critical for effective disease control. Among diverse diagnostic techniques, lateral flow immunoassay (LFIA) has become a widely used on‐site testing tool, owing ...
Quanyu Ren, Yan Wang, Haoyuan Ma, Jialiang Xie, Jianyou Jin, Rumeng Tian, Hao Yu, Xu Gao, Nanhua Chen   +8 more
wiley   +1 more source

Whole‐Genome Characterization of Rodent Coronaviruses (RCoVs) in Thailand, 2024–2025

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Rodents are recognized as important reservoirs of coronaviruses, contributing to viral diversity and potential zoonotic emergence. However, data on rodent coronaviruses (RCoVs) in Thailand remained limited. This study aimed to determine the prevalence, genetic characteristics, and phylogenetic relationships of RCoVs circulating in rodent populations ...
Chanakarn Nasamran, Supassama Chaiyawong, Supanat Boonyapisitsopa, Napawan Bunpapong, Kamonpan Charoenkul, Alongkorn Amonsin, Xing-Lou Yang   +6 more
wiley   +1 more source