Results 31 to 40 of about 2,244 (118)

Crystallization of Feline Coronavirus Mpro With GC376 Reveals Mechanism of Inhibition

Frontiers in Chemistry, 2022
Coronaviruses infect a variety of hosts in the animal kingdom, and while each virus is taxonomically different, they all infect their host via the same mechanism.
Jimmy Lu, Jimmy Lu, Sizhu Amelia Chen, Sizhu Amelia Chen, Muhammad Bashir Khan, Raelynn Brassard, Raelynn Brassard, Elena Arutyunova, Elena Arutyunova, Tess Lamer, Wayne Vuong, Conrad Fischer, Howard S. Young, John C. Vederas, M. Joanne Lemieux, M. Joanne Lemieux   +15 more
doaj   +1 more source

Epicarditis in a cat caused by feline infectious peritonitis virus: case report [PDF]

Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2020
Feline Infectious Peritonitis (FIP) is a progressive and fatal disease in domestic and wild cats, caused by Feline Infectious Peritonitis Virus (FIPV). The disease is characterized by an immunomediated reaction against the virus in various organs.
G.A. Araujo, E.C. Matta, M.A. Lallo, G.F. Machado, P.R.D. Rocha   +4 more
doaj   +1 more source

Virucidal Efficacy of Blue LED and Far-UVC Light Disinfection against Feline Infectious Peritonitis Virus as a Model for SARS-CoV-2

Viruses, 2021
Transmission of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) occurs through respiratory droplets passed directly from person to person or indirectly through fomites, such as common use surfaces or objects. The aim of this study was to
Amanda Gardner, Sayani Ghosh, Magdalena Dunowska, Gale Brightwell   +3 more
doaj   +1 more source

Suppression of feline coronavirus replication in vitro by cyclosporin A

Veterinary Research, 2012
The feline infectious peritonitis virus (FIPV) is a member of the feline coronavirus family that causes FIP, which is incurable and fatal in cats. Cyclosporin A (CsA), an immunosuppressive agent that targets the nuclear factor pathway of activated T ...
Tanaka Yoshikazu, Sato Yuka, Osawa Shuichi, Inoue Mai, Tanaka Satoka, Sasaki Takashi   +5 more
doaj   +1 more source

Feasibility of conducting intradermal vaccination campaign with inactivated poliovirus vaccine using Tropis intradermal needle free injection system, Karachi, Pakistan

Heliyon, 2017
Background: Administration of intradermal fractional dose of inactivated poliovirus vaccine (fIPV) has proven to be safe and immunogenic; however, its intradermal application using needle and syringe is technically difficult and requires trained ...
Mohammad Tahir Yousafzai, Ali Faisal Saleem, Ondrej Mach, Attaullah Baig, Roland W. Sutter, Anita K.M. Zaidi   +5 more
doaj   +1 more source

Genetic Characteristics and Research Progress of Feline Coronavirus

Shiyan dongwu yu bijiao yixue
Feline coronavirus (FCoV) is classified into two biotypes: feline infectious peritonitis virus (FIPV) and feline enteric coronavirus (FECV). FIPV and FECV might evolve and mutate via genetic recombination and mutation, leading to novel subtypes and ...
TAO Lingyun
doaj   +1 more source

A Biopsychosocial and Interprofessional Approach to the Treatment of Family and Intimate Partner Violence: It Takes a Village

Frontiers in Psychiatry, 2021
Family and intimate partner violence and abuse (FIPV) is a critical public health problem with repercussions for mental and physical health. FIPV exposure also is associated with social difficulties such as low socioeconomic status, legal issues, poor ...
Ellen Poleshuck, Marsha N. Wittink, Hugh Crean, Iwona Juskiewicz, Michelle A. ReQua, Catherine Cerulli   +5 more
doaj   +1 more source

Diversity for endoribonuclease nsp15-mediated regulation of alpha-coronavirus propagation and virulence

Microbiology Spectrum, 2023
Endoribonuclease non-structural protein 15 (nsp15) (EndoU) is conserved among coronaviruses (CoVs) and is crucial for viral replication, evasion of the innate immune system, and virulence.
Yunfei Xie, Chener Chen, Ding Zhang, Zhe Jiao, Yixi Chen, Gang Wang, Yubei Tan, Wanpo Zhang, Shaobo Xiao, Guiqing Peng, Yuejun Shi   +10 more
doaj   +1 more source

Development of Feline Ileum- and Colon-Derived Organoids and Their Potential Use to Support Feline Coronavirus Infection

Cells, 2020
Feline coronaviruses (FCoVs) infect both wild and domestic cat populations world-wide. FCoVs present as two main biotypes: the mild feline enteric coronavirus (FECV) and the fatal feline infectious peritonitis virus (FIPV).
Gergely Tekes, Rosina Ehmann, Steeve Boulant, Megan L. Stanifer   +3 more
doaj   +1 more source

Antiviral Effects of Hydroxychloroquine and Type I Interferon on In Vitro Fatal Feline Coronavirus Infection

Viruses, 2020
Feline infectious peritonitis (FIP) is a viral disease with a high morbidity and mortality by the FIP virus (FIPV, virulent feline coronavirus). Several antiviral drugs for FIP have been identified, but many of these are expensive and not available in ...
Tomomi Takano, Kumi Satoh, Tomoyoshi Doki, Taishi Tanabe, Tsutomu Hohdatsu   +4 more
doaj   +1 more source