Pathogens, 2020 Feline infectious peritonitis (FIP) is a fatal feline immune-mediated disease caused by feline infectious peritonitis virus (FIPV). Little is known about the biological pathways associated in FIP pathogenesis.
Shing Wei Ng +4 more
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In Vivo Antiviral Effects of U18666A Against Type I Feline Infectious Peritonitis Virus
Pathogens, 2020 Background: The cationic amphiphilic drug U18666A inhibits the proliferation of type I FIPV in vitro. In this study, we evaluated the in vivo antiviral effects of U18666A by administering it to SPF cats challenged with type I FIPV.
Tomoyoshi Doki +3 more
doaj +1 more source
In Vitro Effects of Doxycycline on Replication of Feline Coronavirus
Pathogens, 2021 Feline infectious peritonitis (FIP) is a sporadic fatal disease of cats caused by a virulent variant of feline coronavirus (FCoV), referred to as FIP virus (FIPV).
Magdalena Dunowska, Sayani Ghosh
doaj +1 more source
The nucleoside analog GS-441524 strongly inhibits feline infectious peritonitis (FIP) virus in tissue culture and experimental cat infection studies. [PDF]
, 2018 Feline infectious peritonitis (FIP) is a common and highly lethal coronavirus disease of domestic cats. Recent studies of diseases caused by several RNA viruses in people and other species indicate that antiviral therapy may be effective against FIP in ...
Bauer, K +7 more
core +1 more source
Crystallization of Feline Coronavirus Mpro With GC376 Reveals Mechanism of Inhibition
Frontiers in Chemistry, 2022 Coronaviruses infect a variety of hosts in the animal kingdom, and while each virus is taxonomically different, they all infect their host via the same mechanism.
Jimmy Lu +15 more
doaj +1 more source
Feline infectious peritonitis: role of the feline coronavirus 3c gene in intestinal tropism and pathogenicity based upon isolates from resident and adopted shelter cats. [PDF]
, 2012 Feline infectious peritonitis virus (FIPV) was presumed to arise from mutations in the 3c of a ubiquitous and largely nonpathogenic feline enteric coronavirus (FECV).
Golovko, Lyudmila +6 more
core +1 more source
Epicarditis in a cat caused by feline infectious peritonitis virus: case report [PDF]
Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2020 Feline Infectious Peritonitis (FIP) is a progressive and fatal disease in domestic and wild cats, caused by Feline Infectious Peritonitis Virus (FIPV). The disease is characterized by an immunomediated reaction against the virus in various organs.
G.A. Araujo +4 more
doaj +1 more source
Sequence Analysis of CCV and its Relationship to FIPV, TGEV and PRCV [PDF]
, 1994 Canine coronavirus (CCV), a causative agent of enteritis in newborn dogs, was first identified in 19711. The disease is characterized by infection of the absorptive epithelium of the villi and the onset of diarrhoea followed by villus atrophy2. The CCV virion is known to contain at least three protein species viz. the 204 kDa spike glycoprotein, S, the
B C, Horsburgh, T D, Brown
openaire +2 more sources
Ultrastructure of SARS-CoV, FIPV, and MHV Revealed by Electron Cryomicroscopy [PDF]
, 2006 * The Scripps Research Institute, La Jolla, California. The current understanding of coronavirus ultrastructure relies heavily on transmission electron microscopy of negatively stained images. Such images typically show desiccated specimens and derive contrast from the accumulation of heavy metal negative stains, distorting the sample in the resulting ...
Neuman, Benjamin W. +6 more
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Levels of feline infectious peritonitis virus in blood, effusions, and various tissues and the role of lymphopenia in disease outcome following experimental infection. [PDF]
, 2015 Twenty specific pathogen free cats were experimentally infected with a virulent cat-passaged type I field strain of FIPV. Eighteen cats succumbed within 2-4 weeks to effusive abdominal FIP, one survived for 6 weeks, and one seroconverted without outward ...
Eckstrand, Chrissy +4 more
core +2 more sources