Results 41 to 50 of about 1,259,430 (273)
COVID-19 Public Sentiment Insights and Machine Learning for Tweets Classification
, 2020 Along with the Coronavirus pandemic, another crisis has manifested itself in the form of mass fear and panic phenomena, fueled by incomplete and often inaccurate information.
Ali, G. G. Md. Nawaz +4 more
core +1 more source
Protection from infection and reinfection due to the Omicron BA.1 variant in care homes
Frontiers in Immunology, 2023 IntroductionFollowing the emergence of SARS-CoV-2 in 2020, care homes were disproportionately impacted by high mortality and morbidity of vulnerable elderly residents.
Saher Choudhry +10 more
doaj +1 more source
Purification and electron cryomicroscopy of coronavirus particles. [PDF]
, 2008 Intact, enveloped coronavirus particles vary widely in size and contour, and are thus refractory to study by traditional structural means such as X-ray crystallography. Electron microscopy (EM) overcomes some problems associated with particle variability
Adair, Brian D +3 more
core +1 more source
Veterinary Microbiology, 1993 Coronaviruses (CV) infect a variety of livestock, poultry and companion animals. They belong to at least five antigenic groups. CV cause localized infections of the respiratory and/or intestinal tracts, with the exception of feline infectious peritonitis virus (FIPV) and hemagglutinating encephalomyelitis (HEV) which cause systemic infections.
openaire +2 more sources
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
The Ecuador Journal of Medicine, 2023 MEDICINA EN PRIMERA LÍNEA, te llevará a apreciar el sacrificio por el que han atravesado nuestros héroes de capa blanca, junto a todo el personal sanitario, durante la pandemia originada por ese enemigo invisible que llegó a transformar la historia del mundo para siempre. Cada página de este sentido libro, plasma Historias de Esfuerzo y Dedicación,
+5 more sources
Fluoxetine Can Inhibit SARS-CoV-2 In Vitro
Microorganisms, 2021 An outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) resulted in the coronavirus disease pandemic, drastically affecting global health and economy.
Arthur Dechaumes +7 more
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
The development of Nanosota-1 as anti-SARS-CoV-2 nanobody drug candidates
eLife, 2021 Combating the COVID-19 pandemic requires potent and low-cost therapeutics. We identified a series of single-domain antibodies (i.e., nanobody), Nanosota-1, from a camelid nanobody phage display library. Structural data showed that Nanosota-1 bound to the
Gang Ye +14 more
doaj +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source