Results 181 to 190 of about 5,490,593 (301)

Mixed lineage kinase 3 mediates SARS‐CoV‐2‐induced kidney injury via the Hsp70‐IL‐17A axis

open access: yesInterdisciplinary Medicine, EarlyView.
Kidney samples from patients infected with severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) showed upregulated expression and activity of Mixed Lineage Kinase (MLK3). Based on the mechanistic studies, we identified MLK3 as a critical player in promoting SARS‐CoV‐2‐induced kidney injury.
Sandeep Kumar   +18 more
wiley   +1 more source

Integrated one‐pot CRISPR‐Cas detection: Addressing strategies and future prospects

open access: yesInterdisciplinary Medicine, EarlyView.
Integrated one‐pot CRISPR‐Cas detection significantly simplifies workflows, reduces cross‐contamination risks, and shortens turnaround times, making it highly suitable for point‐of‐care testing (POCT) and resource‐limited settings. Key challenges include system compatibility issues between Cas proteins and isothermal amplification, limited multiplexing
Jian Zhou   +6 more
wiley   +1 more source

Examining the Directional Effects of Insomnia, Anxiety, and Depression Symptoms: Results From a Longitudinal Study Conducted During the COVID‐19 Pandemic

open access: yesJournal of Clinical Psychology, EarlyView.
ABSTRACT Objectives While some research suggests that increases in anxiety symptoms drive changes in insomnia and depression symptoms, other studies support that these relations may be bidirectional. The present study therefore aimed to further examine how anxiety, insomnia and depression symptoms predict changes in these symptoms over time.
Jamie Walker   +4 more
wiley   +1 more source

Health alert: Coronavirus disease 2019 (COVID-19) [Spanish]

open access: yes
Health alert: Coronavirus disease 2019 (COVID-19) [Spanish]Hace poco estuvo de viaje en un crucero por ri\u301o o por mar.COVID-19 es una enfermedad respiratoria que se puede transmitir de persona a persona.Visite el sitio web para obtener ma\u301s ...

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Variations in trajectories of emotional and behavioural symptoms in children and young people with pre‐existing mental health and neurodevelopmental conditions before and during the COVID‐19 pandemic: A nested data linkage clinical cohort study

open access: yesJCPP Advances, EarlyView.
Abstract Background Children and young people with pre‐existing mental health and neurodevelopmental conditions may have experienced heterogeneous mental health impacts during the COVID‐19 pandemic, but what facts may explain these variations are still unclear. We aimed to examine variations in the longitudinal trajectories of emotional and behavioural
Brian C. F. Ching   +8 more
wiley   +1 more source

Patient and hospitalization differences in incarcerated versus nonincarcerated men: Insights from a 10‐year cohort study

open access: yesJournal of Hospital Medicine, EarlyView.
Abstract Background The incarcerated population in the United States is underserved and aging rapidly; there is a dearth of information regarding their health, including hospital care. Epidemiological information is crucial to guide policymakers’ planning.
Farah Acher Kaiksow   +5 more
wiley   +1 more source

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